RU2684616C2 - Стероидное соединение для применения в лечении печеночной энцефалопатии - Google Patents
Стероидное соединение для применения в лечении печеночной энцефалопатии Download PDFInfo
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- RU2684616C2 RU2684616C2 RU2016127558A RU2016127558A RU2684616C2 RU 2684616 C2 RU2684616 C2 RU 2684616C2 RU 2016127558 A RU2016127558 A RU 2016127558A RU 2016127558 A RU2016127558 A RU 2016127558A RU 2684616 C2 RU2684616 C2 RU 2684616C2
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- Prior art keywords
- hepatic encephalopathy
- hydroxyandrostan
- rats
- ethynyl
- oxime
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| PCT/GB2015/050060 WO2015114308A1 (en) | 2014-01-29 | 2015-01-14 | Steroid compound for use in the treatment of hepatic encephalopathy |
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| RU2016127558A3 RU2016127558A3 (https=) | 2018-09-27 |
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| AR103384A1 (es) | 2015-01-12 | 2017-05-03 | Umecrine Cognition Ab | 3a-ETINILO, 3b-HIDROXI, 5a-PREGNAN-20-OXIMA COMO MODULADOR DE GABA |
| US10278977B2 (en) | 2016-06-06 | 2019-05-07 | Umecrine Cognition Ab | Methods for treating hypersomnolence |
| DK3668927T3 (da) | 2017-09-12 | 2024-03-25 | Eth Zuerich | Transmembran ph-gradient polymersom til kvantificering af ammoniak i kropsvæsker |
| EP3716954A1 (en) * | 2017-11-27 | 2020-10-07 | Umecrine Cognition AB | Pharmaceutical formulation of 3 -ethynyl-3 -hydroxyandrostan-17-one oxime |
| EP4079307A1 (en) | 2021-04-20 | 2022-10-26 | Umecrine Cognition AB | New medical use |
| US20230134958A1 (en) * | 2021-10-29 | 2023-05-04 | Umecrine Cognition Ab | New medical treatment |
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| WO2007103162A2 (en) * | 2006-03-01 | 2007-09-13 | Samaritan Pharmaceuticals, Inc. | Structure based drug design of steroidogenesis inhibitors |
| WO2008063128A1 (en) * | 2006-11-21 | 2008-05-29 | Umecrine Ab | The use of pregnane and androstane steroids for the manufacture of a pharmaceutical composition for the treatment of cns disorders |
| RU2358733C2 (ru) * | 2001-12-06 | 2009-06-20 | ЭЙСАЙ Ар ЭНД Ди МЕНЕДЖМЕНТ КО.,ЛТД. | Фармацевтические композиции и их применения |
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| US2713061A (en) | 1951-04-06 | 1955-07-12 | Schering Ag | 3-methyl androstanes |
| FR1463755A (fr) | 1960-01-26 | 1966-07-22 | Nouveaux stéroïdes de la série de l'androstane et leur procédé de préparation | |
| US3173932A (en) | 1962-11-02 | 1965-03-16 | American Cyanamid Co | 15-substituted estra-1, 3, 5(10)-trienes |
| FR2685332A1 (fr) | 1991-12-20 | 1993-06-25 | Roussel Uclaf | Nouveaux 19-nor sterouides ayant en position 11beta une chaine thiocarbonee, leur procede de preparation et les intermediaires et leur application a titre de medicaments. |
| DE69435286D1 (de) | 1993-05-24 | 2010-05-20 | Purdue Pharma Ltd | Verfahren und zusammensetzungen zum hervorrufen von schlaf |
| AU756001B2 (en) | 1998-03-11 | 2003-01-02 | Umecrine Mood Ab | Epiallopregnanolone in the treatment of CNS disorders |
| US6593321B2 (en) | 2001-06-11 | 2003-07-15 | Southwest Foundation For Biomedical Research | 2-alkoxyestradiol analogs with antiproliferative and antimitotic activity |
| SE0104423D0 (sv) * | 2001-12-27 | 2001-12-27 | Umecrine Ab | Pregnane steroids and their use in the treatment of CNS disorders |
| SI2153870T1 (sl) | 2004-11-26 | 2014-05-30 | Ucl Business Plc | Sestavki, ki obsegajo ornitin in fenilacetat ali fenilbutirat, za zdravljenje hepatitične encefalopatije |
| GB0711948D0 (en) | 2007-06-20 | 2007-08-01 | Bionature E A Ltd | Neurosteriod compounds |
| CN101585862B (zh) * | 2008-05-20 | 2014-12-17 | 梅克芳股份公司 | 甾族化合物 |
| HRP20200284T1 (hr) * | 2008-10-02 | 2020-07-10 | Salix Pharmaceuticals, Ltd. | Postupci liječenja hepatičke encefalopatije |
| CN104434894A (zh) | 2009-06-08 | 2015-03-25 | Ucl商业有限公司 | 使用l-鸟氨酸苯乙酸盐治疗门静脉高压和恢复肝功能 |
| WO2015048818A1 (en) | 2013-09-30 | 2015-04-02 | Hyperion Therapeutics, Inc. | Diagnosing, grading, monitoring, and treating hepatic encephalopathy |
| RU2684616C2 (ru) | 2014-01-29 | 2019-04-10 | Умекрин Когнишн Аб | Стероидное соединение для применения в лечении печеночной энцефалопатии |
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- 2015-01-14 ME MEP-2019-39A patent/ME03351B/me unknown
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- 2015-01-14 SI SI201530591T patent/SI3099306T1/sl unknown
- 2015-01-14 HR HRP20190251TT patent/HRP20190251T1/hr unknown
- 2015-01-14 CN CN202110480203.5A patent/CN113185566A/zh active Pending
- 2015-01-14 CA CA2935015A patent/CA2935015C/en active Active
- 2015-01-14 CN CN201580006600.1A patent/CN106163528A/zh active Pending
- 2015-01-14 WO PCT/GB2015/050060 patent/WO2015114308A1/en not_active Ceased
- 2015-01-14 US US15/114,972 patent/US20160339040A1/en not_active Abandoned
- 2015-01-14 HU HUE15705691A patent/HUE042242T2/hu unknown
- 2015-01-14 AU AU2015212606A patent/AU2015212606B2/en active Active
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2016
- 2016-06-28 IL IL246496A patent/IL246496B/en active IP Right Grant
- 2016-11-15 US US15/352,035 patent/US9801894B2/en active Active
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2017
- 2017-09-27 US US15/716,838 patent/US10342804B2/en active Active
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2019
- 2019-03-12 CY CY20191100299T patent/CY1121464T1/el unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2358733C2 (ru) * | 2001-12-06 | 2009-06-20 | ЭЙСАЙ Ар ЭНД Ди МЕНЕДЖМЕНТ КО.,ЛТД. | Фармацевтические композиции и их применения |
| WO2007103162A2 (en) * | 2006-03-01 | 2007-09-13 | Samaritan Pharmaceuticals, Inc. | Structure based drug design of steroidogenesis inhibitors |
| WO2008063128A1 (en) * | 2006-11-21 | 2008-05-29 | Umecrine Ab | The use of pregnane and androstane steroids for the manufacture of a pharmaceutical composition for the treatment of cns disorders |
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