RU2673723C1 - Применение содержащих изоксазолин соединений в качестве противопаразитарных средств - Google Patents

Применение содержащих изоксазолин соединений в качестве противопаразитарных средств Download PDF

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Publication number
RU2673723C1
RU2673723C1 RU2016127304A RU2016127304A RU2673723C1 RU 2673723 C1 RU2673723 C1 RU 2673723C1 RU 2016127304 A RU2016127304 A RU 2016127304A RU 2016127304 A RU2016127304 A RU 2016127304A RU 2673723 C1 RU2673723 C1 RU 2673723C1
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RU
Russia
Prior art keywords
isoxazoline
fleas
trifluoromethyl
methyl
fluralaner
Prior art date
Application number
RU2016127304A
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English (en)
Russian (ru)
Inventor
Хайке ВИЛЛЬЯМС
Хартмут ЦОЛЛЕР
Аня Регина ХЕККЕРОТ
Original Assignee
Интервет Интернэшнл Б.В.
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Application filed by Интервет Интернэшнл Б.В. filed Critical Интервет Интернэшнл Б.В.
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2016127304A 2013-12-10 2014-12-09 Применение содержащих изоксазолин соединений в качестве противопаразитарных средств RU2673723C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13196539 2013-12-10
EP13196539.4 2013-12-10
PCT/EP2014/076959 WO2015086551A1 (en) 2013-12-10 2014-12-09 Antiparasitic use of isoxazoline compounds

Publications (1)

Publication Number Publication Date
RU2673723C1 true RU2673723C1 (ru) 2018-11-29

Family

ID=49759099

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016127304A RU2673723C1 (ru) 2013-12-10 2014-12-09 Применение содержащих изоксазолин соединений в качестве противопаразитарных средств

Country Status (14)

Country Link
US (1) US9655884B2 (enExample)
EP (1) EP3079474B1 (enExample)
JP (1) JP6530753B2 (enExample)
CN (1) CN105992517B (enExample)
AU (1) AU2014363695B2 (enExample)
BR (1) BR112016013020B1 (enExample)
CA (1) CA2932790C (enExample)
DK (1) DK3079474T3 (enExample)
ES (1) ES2742815T3 (enExample)
HU (1) HUE046067T2 (enExample)
PL (1) PL3079474T3 (enExample)
PT (1) PT3079474T (enExample)
RU (1) RU2673723C1 (enExample)
WO (1) WO2015086551A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2823297C1 (ru) * 2023-11-20 2024-07-22 Общество с ограниченной ответственностью "ВЕТФАРМСТАНДАРТ" Ветеринарный фармацевтический продукт против эктопаразитов собак

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017027855B1 (pt) 2015-06-23 2022-11-16 Intervet International B.V. Composição farmacêutica, seu uso, água potável medicamentosa e método para sua preparação
CN107535510A (zh) * 2017-09-29 2018-01-05 北京科发伟业农药技术中心 一种含fluralaner的组合物
EP3723483B1 (en) 2017-12-12 2025-09-03 Intervet International B.V. Implantable fluralaner pharmaceutical compositions and uses thereof
BR112022000982A2 (pt) 2019-07-22 2022-03-08 Intervet Int Bv Forma de dosagem veterinária mastigável macia
EP4075981A1 (en) * 2019-12-16 2022-10-26 Intervet International B.V. Composition for lice control
US12497370B2 (en) 2019-12-18 2025-12-16 Elanco Tiergesundheit Ag Isoxazoline derivatives
US12655138B2 (en) 2020-07-24 2026-06-16 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof
AU2021335500A1 (en) 2020-09-04 2023-05-04 Elanco Us Inc. Palatable formulations
WO2022192623A1 (en) * 2021-03-11 2022-09-15 In The Bowl Animal Health, Inc. Oral canine feed and methods for controlling flea infestations in a canine
WO2022271961A1 (en) * 2021-06-25 2022-12-29 In The Bowl Animal Health, Inc. Oral feline feed and methods for controlling tick infestations in a feline
DK182016B1 (en) 2023-03-13 2025-05-28 Zoetis Services Llc Degradation of isoxazolines in ozonated sea water

Citations (4)

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Publication number Priority date Publication date Assignee Title
EP1119256B1 (en) * 1998-10-09 2003-06-04 Novartis AG Oral combination of lufenuron and nitenpyram against fleas
WO2009024541A2 (en) * 2007-08-17 2009-02-26 Intervet International B.V. Isoxazoline compositions and their use as antiparasitics
RU2473541C9 (ru) * 2007-04-23 2013-06-20 Байер Кропсайенс Аг Инсектицидные арилпирролидины
WO2013150055A1 (en) * 2012-04-04 2013-10-10 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds

Family Cites Families (13)

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WO1984001100A1 (en) 1982-09-17 1984-03-29 Edward Ireland Improved dental matrix band
BR9710910A (pt) * 1996-08-02 1999-08-17 Novartis Ag Processo aperfei-oado para administra-Æo sist-mica de inseticidas do tipo cido 2,4-dienÄico a mamiferos terrestres
EP1671941A4 (en) 2003-09-30 2007-12-12 Nissan Chemical Ind Ltd SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT
BRPI0508140B1 (pt) 2004-03-05 2015-03-17 Nissan Chemical Ind Ltd Composto benzamida substituída por isoxazolina da fórmula (1); da fórmula (2) substituído por 3,5-bis (aril substituído); da fórmula (4) substituída por alquinibenzeno ou um sal do mesmo; "pesticida, agroquímico, inseticida, parasiticida contendo como ingrediente ativo um ou mais composto benzamida substituída por isoxazolina e sal do mesmo"
TWI412322B (zh) 2005-12-30 2013-10-21 杜邦股份有限公司 控制無脊椎害蟲之異唑啉
EP2151437A4 (en) 2007-03-07 2012-05-02 Nissan Chemical Ind Ltd ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT
DE102007028871A1 (de) 2007-06-22 2008-12-24 Clariant International Limited Verfahren zur Herstellung von reinem C.I. Pigment Orange 74
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2182945T3 (en) 2007-06-27 2015-11-16 Du Pont PROCEDURE TO COMBAT PESTS WITH ANIMALS
TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
ES2442342T3 (es) 2008-12-18 2014-02-11 Novartis Ag Derivados de las isoxazolinas y su uso como pesticida
AR074790A1 (es) 2008-12-19 2011-02-09 Novartis Ag Derivados de isooxazol sustituidos, composiciones farmaceuticas y para el control de parasitos que los comprenden y su uso en metodos para controlar parasitos en y sobre animales de sangre caliente.
AP2014007874A0 (en) 2012-02-06 2014-08-31 Merial Ltd Parasiticidal oral veterinary compositions comprising systemetically- acting active agents, methods and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1119256B1 (en) * 1998-10-09 2003-06-04 Novartis AG Oral combination of lufenuron and nitenpyram against fleas
RU2473541C9 (ru) * 2007-04-23 2013-06-20 Байер Кропсайенс Аг Инсектицидные арилпирролидины
WO2009024541A2 (en) * 2007-08-17 2009-02-26 Intervet International B.V. Isoxazoline compositions and their use as antiparasitics
WO2013150055A1 (en) * 2012-04-04 2013-10-10 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2823297C1 (ru) * 2023-11-20 2024-07-22 Общество с ограниченной ответственностью "ВЕТФАРМСТАНДАРТ" Ветеринарный фармацевтический продукт против эктопаразитов собак
RU2847348C1 (ru) * 2024-04-27 2025-10-03 Общество С Ограниченной Ответственностью "Научно-Исследовательский Центр "Фарматол" Противопаразитарное средство для лечения и профилактики эктопаразитозов собак.
RU2847346C1 (ru) * 2024-05-13 2025-10-03 Общество С Ограниченной Ответственностью "Научно-Исследовательский Центр "Фарматол" Противопаразитарное средство для лечения и профилактики эктопаразитозов собак и кошек

Also Published As

Publication number Publication date
PL3079474T3 (pl) 2019-10-31
JP6530753B2 (ja) 2019-06-12
BR112016013020A2 (pt) 2017-08-08
BR112016013020B1 (pt) 2020-12-01
HUE046067T2 (hu) 2020-02-28
EP3079474A1 (en) 2016-10-19
PT3079474T (pt) 2019-09-10
US20160303086A1 (en) 2016-10-20
JP2016539960A (ja) 2016-12-22
EP3079474B1 (en) 2019-07-03
CA2932790A1 (en) 2015-06-18
DK3079474T3 (da) 2019-09-16
AU2014363695A1 (en) 2016-06-09
CN105992517B (zh) 2020-03-06
US9655884B2 (en) 2017-05-23
AU2014363695B2 (en) 2018-12-13
CN105992517A (zh) 2016-10-05
CA2932790C (en) 2021-10-12
ES2742815T3 (es) 2020-02-17
WO2015086551A1 (en) 2015-06-18

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