RU2671955C2 - Лечение сосудистого заболевания и его осложнений - Google Patents

Лечение сосудистого заболевания и его осложнений Download PDF

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Publication number
RU2671955C2
RU2671955C2 RU2015110635A RU2015110635A RU2671955C2 RU 2671955 C2 RU2671955 C2 RU 2671955C2 RU 2015110635 A RU2015110635 A RU 2015110635A RU 2015110635 A RU2015110635 A RU 2015110635A RU 2671955 C2 RU2671955 C2 RU 2671955C2
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RU
Russia
Prior art keywords
restenosis
likelihood
monoclonal antibody
antibody
stenosis
Prior art date
Application number
RU2015110635A
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English (en)
Russian (ru)
Other versions
RU2015110635A (ru
Inventor
Джон СИМАРД
Original Assignee
ИксБиотеч, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by ИксБиотеч, Инк. filed Critical ИксБиотеч, Инк.
Publication of RU2015110635A publication Critical patent/RU2015110635A/ru
Application granted granted Critical
Publication of RU2671955C2 publication Critical patent/RU2671955C2/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/245IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
RU2015110635A 2012-10-04 2013-10-01 Лечение сосудистого заболевания и его осложнений RU2671955C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261709754P 2012-10-04 2012-10-04
US61/709,754 2012-10-04
PCT/US2013/062903 WO2014055544A1 (en) 2012-10-04 2013-10-01 Treating vascular disease and complications thereof

Publications (2)

Publication Number Publication Date
RU2015110635A RU2015110635A (ru) 2016-11-27
RU2671955C2 true RU2671955C2 (ru) 2018-11-08

Family

ID=50432830

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2015110635A RU2671955C2 (ru) 2012-10-04 2013-10-01 Лечение сосудистого заболевания и его осложнений

Country Status (12)

Country Link
US (3) US20140099321A1 (enExample)
EP (3) EP4628162A3 (enExample)
JP (1) JP6460993B2 (enExample)
KR (2) KR102296017B1 (enExample)
CN (2) CN104684929A (enExample)
AU (1) AU2013327501B2 (enExample)
CA (1) CA2886747C (enExample)
HK (1) HK1211960A1 (enExample)
IL (1) IL237765B (enExample)
MX (1) MX376241B (enExample)
RU (1) RU2671955C2 (enExample)
WO (1) WO2014055544A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6324720B2 (ja) 2010-06-18 2018-05-16 エックスバイオテク, インコーポレイテッドXbiotech, Inc. 関節炎治療
KR102748255B1 (ko) 2010-08-23 2024-12-31 엑스바이오테크 인코포레이티드 종양성 질병들에 대한 치료
US9724409B2 (en) 2011-04-01 2017-08-08 Xbiotech, Inc. Treatment of inflammatory skin disease
JP6204915B2 (ja) 2011-09-23 2017-09-27 エックスバイオテク, インコーポレイテッドXbiotech, Inc. 悪液質治療
US9545441B2 (en) 2012-09-18 2017-01-17 Xbiotech, Inc. Treatment of diabetes
KR20190117579A (ko) 2017-02-16 2019-10-16 엑스바이오테크, 인크. 화농성 한선염의 치료
CN113874034A (zh) * 2019-05-03 2021-12-31 苏黎世大学 脑缺血再灌注损伤的治疗
KR102652849B1 (ko) 2022-03-14 2024-04-01 한국화학연구원 극성 아라미드 나노섬유로 제조한 하이드로겔

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2235541C2 (ru) * 1994-10-04 2004-09-10 Эмори Юниверсити Лечение атеросклероза и других сердечно-сосудистых и воспалительных заболеваний
US20120015384A1 (en) * 2008-05-30 2012-01-19 Xbiotech, Inc. Interleukin-1 Alpha Antibodies and Methods of Use

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CH652145A5 (de) 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
JP2003500069A (ja) * 1999-05-24 2003-01-07 インタールーキン ジェネティックス インク 再狭窄の診断及び治療薬
EP1471931A4 (en) * 2001-08-24 2006-06-14 Maine Medical Ct Res Inst NON-TRADITIONAL EXPORT OF COPPER-DEPENDENT PRO-INFLAMMATORY CYTOKINES AND METHODS, COMPOSITIONS, AND KITS THEREOF
WO2004100987A2 (en) * 2003-05-06 2004-11-25 Regeneron Pharmaceuticals, Inc. Methods of using il-1 antagonists to treat neointimal hyperplasia
CN107243077A (zh) * 2009-05-29 2017-10-13 爱克索马美国有限责任公司 IL‑1β抗体及其结合片段的心血管相关用途
JP5812669B2 (ja) 2011-04-27 2015-11-17 キヤノン株式会社 画像処理装置および画像処理方法およびコンピュータプログラム。

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2235541C2 (ru) * 1994-10-04 2004-09-10 Эмори Юниверсити Лечение атеросклероза и других сердечно-сосудистых и воспалительных заболеваний
US20120015384A1 (en) * 2008-05-30 2012-01-19 Xbiotech, Inc. Interleukin-1 Alpha Antibodies and Methods of Use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MORTON A.C. et al. Interleukin-1 receptor antagonist alters the response to vessel wall injury in a porcine coronary artery model //Cardiovascular Research, Volume 68, Issue 3, 1 December 2005, Pages 493-501, https://doi.org/10.1016/j.cardiores.2005.06.026. *

Also Published As

Publication number Publication date
WO2014055544A1 (en) 2014-04-10
HK1211960A1 (en) 2016-06-03
KR20210108496A (ko) 2021-09-02
EP3524621A1 (en) 2019-08-14
AU2013327501A1 (en) 2015-04-02
IL237765B (en) 2019-06-30
MX376241B (es) 2025-03-06
KR102296017B1 (ko) 2021-09-01
IL237765A0 (en) 2015-05-31
CA2886747C (en) 2023-12-05
CN104684929A (zh) 2015-06-03
AU2013327501B2 (en) 2018-08-09
US20180057585A1 (en) 2018-03-01
US20140099321A1 (en) 2014-04-10
RU2015110635A (ru) 2016-11-27
MX2015004286A (es) 2015-08-06
JP6460993B2 (ja) 2019-01-30
JP2015531397A (ja) 2015-11-02
EP4628162A2 (en) 2025-10-08
CN113018431A (zh) 2021-06-25
KR20150063076A (ko) 2015-06-08
EP4628162A3 (en) 2025-12-03
US20210403548A1 (en) 2021-12-30
CA2886747A1 (en) 2014-04-10
EP2904010A1 (en) 2015-08-12
EP2904010A4 (en) 2016-06-01
KR102429919B1 (ko) 2022-08-05

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Effective date: 20210526

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