RU2664431C2 - Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания - Google Patents

Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания Download PDF

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RU2664431C2
RU2664431C2 RU2013131239A RU2013131239A RU2664431C2 RU 2664431 C2 RU2664431 C2 RU 2664431C2 RU 2013131239 A RU2013131239 A RU 2013131239A RU 2013131239 A RU2013131239 A RU 2013131239A RU 2664431 C2 RU2664431 C2 RU 2664431C2
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il1b
allele
periodontal disease
il1b3877
patient
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RU2013131239A
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RU2013131239A (ru
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Кеннет КОРНМАН
Сяодун У
Хва-Ин ВАН
Джон РОГАС
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ОриджЗн, Инк.
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/18Dental and oral disorders

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
RU2013131239A 2010-12-09 2011-12-09 Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания RU2664431C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42162810P 2010-12-09 2010-12-09
US61/421,628 2010-12-09
US201161452157P 2011-03-13 2011-03-13
US61/452,157 2011-03-13
PCT/US2011/064216 WO2012079010A2 (en) 2010-12-09 2011-12-09 Improved method and kit for determining severity and progression of periodontal disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2018122965A Division RU2018122965A (ru) 2010-12-09 2011-12-09 Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания

Publications (2)

Publication Number Publication Date
RU2013131239A RU2013131239A (ru) 2015-01-20
RU2664431C2 true RU2664431C2 (ru) 2018-08-17

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RU2018122965A RU2018122965A (ru) 2010-12-09 2011-12-09 Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания
RU2013131239A RU2664431C2 (ru) 2010-12-09 2011-12-09 Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания

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RU2018122965A RU2018122965A (ru) 2010-12-09 2011-12-09 Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания

Country Status (10)

Country Link
US (3) US20120208187A1 (OSRAM)
EP (1) EP2649203B1 (OSRAM)
JP (2) JP6138692B2 (OSRAM)
CN (1) CN103547680B (OSRAM)
AU (2) AU2011338210B2 (OSRAM)
BR (1) BR112013014479B1 (OSRAM)
NZ (2) NZ612799A (OSRAM)
RU (2) RU2018122965A (OSRAM)
SG (1) SG191078A1 (OSRAM)
WO (1) WO2012079010A2 (OSRAM)

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CN106918706B (zh) * 2015-12-25 2019-05-21 广州瑞博奥生物科技有限公司 一种检测牙周病相关蛋白的抗体芯片试剂盒
WO2017123696A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10337070B2 (en) 2017-01-12 2019-07-02 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
GB201818627D0 (en) * 2018-11-15 2019-01-02 Mars Inc Analytical systems
JP7097855B2 (ja) * 2019-04-24 2022-07-08 ジェネシスヘルスケア株式会社 歯周病のリスクを判定する方法
CA3142662A1 (en) 2019-06-06 2020-12-10 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19
KR102571131B1 (ko) * 2021-06-01 2023-08-24 부산대학교 산학협력단 치주염 감별용 바이오마커 조성물, 치주염 중증도 감별용 바이오마커 조성물, 및 이를 이용한 진단 키트
US20250046463A1 (en) * 2021-11-12 2025-02-06 Mars, Incorporated Systems and methods for generating health reports based on veterinary oral care health test

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WO1997006180A1 (en) * 1995-08-03 1997-02-20 Medical Science Systems, Inc. Detecting genetic predisposition to periodontal disease
US20080118920A1 (en) * 2004-05-03 2008-05-22 Duff Gordon W Diagnostics And Therapeutics For Diseases Associated With An Il-1 Inflammatory Haplotype

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WO1997006180A1 (en) * 1995-08-03 1997-02-20 Medical Science Systems, Inc. Detecting genetic predisposition to periodontal disease
US20080118920A1 (en) * 2004-05-03 2008-05-22 Duff Gordon W Diagnostics And Therapeutics For Diseases Associated With An Il-1 Inflammatory Haplotype

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CHEN H. et al. Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context. Hum Mol Genet. 2006 Feb 15; 15(4): 519-529. Epub 2006 Jan 6. *
ROGUS J. et al. IL1B gene promoter haplotype pairs predict clinical levels of interleukin-1beta and C-reactive protein. Hum Genet. 2008 May; 123(4): 387-398. Epub 2008 Mar 28. *
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Also Published As

Publication number Publication date
NZ701432A (en) 2016-06-24
EP2649203A2 (en) 2013-10-16
US20120208187A1 (en) 2012-08-16
CN103547680B (zh) 2017-05-24
BR112013014479A2 (pt) 2016-09-20
US9347090B2 (en) 2016-05-24
SG191078A1 (en) 2013-07-31
US20160244841A1 (en) 2016-08-25
JP6138692B2 (ja) 2017-05-31
CN103547680A (zh) 2014-01-29
EP2649203B1 (en) 2019-07-24
JP2017121237A (ja) 2017-07-13
WO2012079010A3 (en) 2012-08-23
AU2016202211A1 (en) 2016-05-05
BR112013014479B1 (pt) 2020-10-27
EP2649203A4 (en) 2014-05-07
AU2016202211B2 (en) 2017-02-23
RU2018122965A3 (OSRAM) 2019-04-11
AU2011338210B2 (en) 2016-05-12
JP6622731B2 (ja) 2019-12-18
US20130337448A1 (en) 2013-12-19
RU2013131239A (ru) 2015-01-20
AU2011338210A1 (en) 2013-07-25
JP2013544536A (ja) 2013-12-19
NZ612799A (en) 2015-04-24
WO2012079010A2 (en) 2012-06-14
RU2018122965A (ru) 2019-03-06

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Effective date: 20191210