RU2643081C2 - Инъектор карандашного типа - Google Patents
Инъектор карандашного типа Download PDFInfo
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- RU2643081C2 RU2643081C2 RU2014144353A RU2014144353A RU2643081C2 RU 2643081 C2 RU2643081 C2 RU 2643081C2 RU 2014144353 A RU2014144353 A RU 2014144353A RU 2014144353 A RU2014144353 A RU 2014144353A RU 2643081 C2 RU2643081 C2 RU 2643081C2
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/59—Aesthetic features, e.g. distraction means to prevent fears of child patients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12163484 | 2012-04-05 | ||
| EP12163484.4 | 2012-04-05 | ||
| US201261666269P | 2012-06-29 | 2012-06-29 | |
| US61/666,269 | 2012-06-29 | ||
| PCT/EP2013/056852 WO2013149979A1 (en) | 2012-04-05 | 2013-04-02 | Pen-type injector |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2014144353A RU2014144353A (ru) | 2016-05-27 |
| RU2643081C2 true RU2643081C2 (ru) | 2018-01-30 |
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|---|---|---|---|
| RU2014144353A RU2643081C2 (ru) | 2012-04-05 | 2013-04-02 | Инъектор карандашного типа |
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| USD737432S1 (en) * | 2011-06-27 | 2015-08-25 | Ferring B.V. | Medicine applicator |
| AU349331S (en) * | 2012-07-05 | 2013-06-20 | Sanofi Aventis Deutschland | Injection device |
| USD752211S1 (en) * | 2012-08-01 | 2016-03-22 | Sanofi-Aventis Deutschland Gmbh | Injection device |
| AR092276A1 (es) | 2012-08-31 | 2015-04-08 | Sanofi Aventis Deutschland | Dispositivo de administracion de farmacos |
| AU2013310949A1 (en) * | 2012-08-31 | 2015-03-12 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
| CA155282S (en) * | 2013-09-04 | 2015-02-10 | Sanofi Aventis Deutschland | Injection device |
| USD752738S1 (en) * | 2013-09-20 | 2016-03-29 | Sanofi-Aventis Deutschland Gmbh | Injection device |
| USD743538S1 (en) * | 2014-01-17 | 2015-11-17 | Sanofi-Aventis Deutschland Gmbh | Injection device |
| USD777908S1 (en) * | 2014-08-27 | 2017-01-31 | Merck Sharp & Dohme Corp. | Medical injector pen |
| USD773646S1 (en) * | 2014-08-27 | 2016-12-06 | Merck Sharp & Dohme Corp | Medical injector pen |
| USD777907S1 (en) * | 2014-08-27 | 2017-01-31 | Merck Sharp & Dohme Corp. | Medical injector pen |
| RU2017118366A (ru) | 2014-10-28 | 2018-11-30 | БАЙЕР ХелсКер ЛЛСи | Самоориентирующийся кожух высокого давления и механизм стыковки кожуха высокого давления и инъектора |
| AU2015339379B2 (en) * | 2014-10-28 | 2020-09-03 | Bayer Healthcare Llc | Self-orienting pressure jacket and pressure jacket-to-injector interface |
| US9199033B1 (en) | 2014-10-28 | 2015-12-01 | Bayer Healthcare Llc | Self-orienting syringe and syringe interface |
| NO2689315T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2014-10-28 | 2018-04-14 | ||
| CN107820447B (zh) * | 2015-06-08 | 2021-07-13 | 康宁股份有限公司 | 可读性和韧性得到改善的移液管 |
| US11191893B2 (en) | 2018-01-31 | 2021-12-07 | Bayer Healthcare Llc | System and method for syringe engagement with injector |
| CN108837238B (zh) * | 2018-07-13 | 2023-09-01 | 江苏省人民医院（南京医科大学第一附属医院） | 一种玻尿酸注射针 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2826195A (en) * | 1956-05-22 | 1958-03-11 | American Home Prod | Plastic injection syringe |
| US5873861A (en) * | 1996-11-12 | 1999-02-23 | Medrad, Inc. | Plunger systems |
| US6210369B1 (en) * | 1997-12-16 | 2001-04-03 | Meridian Medical Technologies Inc. | Automatic injector |
| WO2010037828A1 (en) * | 2008-10-01 | 2010-04-08 | Novo Nordisk A/S | Medical assembly with monitoring device |
| RU2387461C2 (ru) * | 2004-10-04 | 2010-04-27 | Санофи-Авентис Дойчланд Гмбх | Приводной механизм для устройства введения лекарств |
| US20120209213A1 (en) * | 2010-12-06 | 2012-08-16 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US533575A (en) | 1895-02-05 | wilkens | ||
| US5244465A (en) * | 1988-10-19 | 1993-09-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Reusable injection device for distributing a preselected dose |
| US5226895A (en) | 1989-06-05 | 1993-07-13 | Eli Lilly And Company | Multiple dose injection pen |
| GB9007113D0 (en) | 1990-03-29 | 1990-05-30 | Sams Bernard | Dispensing device |
| ATE121953T1 (de) | 1991-07-24 | 1995-05-15 | Medico Dev Investment Co | Injektor. |
| DK175491D0 (da) | 1991-10-18 | 1991-10-18 | Novo Nordisk As | Apparat |
| US5279585A (en) | 1992-02-04 | 1994-01-18 | Becton, Dickinson And Company | Medication delivery pen having improved dose delivery features |
| US5569189A (en) * | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| US5320609A (en) | 1992-12-07 | 1994-06-14 | Habley Medical Technology Corporation | Automatic pharmaceutical dispensing syringe |
| US5383865A (en) | 1993-03-15 | 1995-01-24 | Eli Lilly And Company | Medication dispensing device |
| ZA941881B (en) | 1993-04-02 | 1995-09-18 | Lilly Co Eli | Manifold medication injection apparatus and method |
| US5582598A (en) | 1994-09-19 | 1996-12-10 | Becton Dickinson And Company | Medication delivery pen with variable increment dose scale |
| WO1996027400A1 (en) | 1995-03-07 | 1996-09-12 | Eli Lilly And Company | Recyclable medication dispensing device |
| US5688251A (en) | 1995-09-19 | 1997-11-18 | Becton Dickinson And Company | Cartridge loading and priming mechanism for a pen injector |
| US5674204A (en) | 1995-09-19 | 1997-10-07 | Becton Dickinson And Company | Medication delivery pen cap actuated dose delivery clutch |
| DE19730999C1 (de) | 1997-07-18 | 1998-12-10 | Disetronic Licensing Ag | Dosierknopfsicherung an einer Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts |
| US5921966A (en) | 1997-08-11 | 1999-07-13 | Becton Dickinson And Company | Medication delivery pen having an improved clutch assembly |
| IL135255A0 (en) | 1998-01-30 | 2001-05-20 | Novo Nordisk As | An injection syringe |
| US6221053B1 (en) | 1998-02-20 | 2001-04-24 | Becton, Dickinson And Company | Multi-featured medication delivery pen |
| US5961495A (en) | 1998-02-20 | 1999-10-05 | Becton, Dickinson And Company | Medication delivery pen having a priming mechanism |
| US6248095B1 (en) | 1998-02-23 | 2001-06-19 | Becton, Dickinson And Company | Low-cost medication delivery pen |
| EP1218042B1 (en) | 1999-08-05 | 2006-02-22 | Becton Dickinson and Company | Medication delivery pen |
| GB0007071D0 (en) | 2000-03-24 | 2000-05-17 | Sams Bernard | One-way clutch mechanisms and injector devices |
| JP3591636B2 (ja) * | 2000-04-03 | 2004-11-24 | ニプロ株式会社 | プレフィルドシリンジ |
| US6663602B2 (en) | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
| US6899699B2 (en) | 2001-01-05 | 2005-05-31 | Novo Nordisk A/S | Automatic injection device with reset feature |
| CA2689020C (en) | 2001-05-16 | 2011-11-08 | Eli Lilly And Company | Medication injector apparatus with drive assembly that facilitates reset |
| GB0304823D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| RU2388498C2 (ru) * | 2004-10-21 | 2010-05-10 | Ново Нордиск А/С | Устройство для инъекций, снабженное торсионной пружиной и поворотным индикатором |
| DE102004063645A1 (de) | 2004-12-31 | 2006-07-20 | Tecpharma Licensing Ag | Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Entkopplung für einen Behältniswechsel |
| WO2006102510A2 (en) * | 2005-03-24 | 2006-09-28 | Cooper-Standard Automotive, Inc. | Positive crankcase ventilation valve assembly with a vacuum pulsation dampener |
| US8241257B2 (en) * | 2008-01-15 | 2012-08-14 | Becton, Dickinson And Company | Pen needle assembly |
| US8647309B2 (en) | 2008-05-02 | 2014-02-11 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
| DE102008052356A1 (de) * | 2008-10-20 | 2010-04-22 | Tecpharma Licensing Ag | Injektionsvorrichtung mit einklickbarem Kanülenträger |
| EP2201974A1 (en) * | 2008-12-23 | 2010-06-30 | Sanofi-Aventis Deutschland GmbH | Medication delivery device |
| US9950116B2 (en) * | 2009-06-01 | 2018-04-24 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
| JP5925692B2 (ja) * | 2009-12-04 | 2016-05-25 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | 多位置キャップを備える自己注射装置 |
| US10207056B2 (en) * | 2010-03-31 | 2019-02-19 | Sanofi-Aventis Deutschland Gmbh | Set of members for a drug delivery device, drug delivery device and set of drug delivery devices |
-
2013
- 2013-04-02 US US14/388,549 patent/US9849245B2/en active Active
- 2013-04-02 EP EP13713198.3A patent/EP2833945B1/en active Active
- 2013-04-02 AU AU2013245105A patent/AU2013245105B2/en active Active
- 2013-04-02 PL PL13713198T patent/PL2833945T3/pl unknown
- 2013-04-02 JP JP2015503845A patent/JP6339558B2/ja active Active
- 2013-04-02 WO PCT/EP2013/056852 patent/WO2013149979A1/en active Application Filing
- 2013-04-02 CN CN201380015710.5A patent/CN104519928B/zh active Active
- 2013-04-02 KR KR1020147028981A patent/KR102144138B1/ko active Active
- 2013-04-02 RU RU2014144353A patent/RU2643081C2/ru active
- 2013-04-02 MX MX2014011994A patent/MX363321B/es unknown
- 2013-04-02 BR BR112014024651-3A patent/BR112014024651B1/pt active IP Right Grant
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2826195A (en) * | 1956-05-22 | 1958-03-11 | American Home Prod | Plastic injection syringe |
| US5873861A (en) * | 1996-11-12 | 1999-02-23 | Medrad, Inc. | Plunger systems |
| US6210369B1 (en) * | 1997-12-16 | 2001-04-03 | Meridian Medical Technologies Inc. | Automatic injector |
| RU2387461C2 (ru) * | 2004-10-04 | 2010-04-27 | Санофи-Авентис Дойчланд Гмбх | Приводной механизм для устройства введения лекарств |
| WO2010037828A1 (en) * | 2008-10-01 | 2010-04-08 | Novo Nordisk A/S | Medical assembly with monitoring device |
| US20120209213A1 (en) * | 2010-12-06 | 2012-08-16 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2014011994A (es) | 2014-11-10 |
| RU2014144353A (ru) | 2016-05-27 |
| JP2015516840A (ja) | 2015-06-18 |
| HK1201220A1 (en) | 2015-08-28 |
| EP2833945B1 (en) | 2020-09-02 |
| JP6339558B2 (ja) | 2018-06-06 |
| CN104519928A (zh) | 2015-04-15 |
| EP2833945A1 (en) | 2015-02-11 |
| MX363321B (es) | 2019-03-20 |
| WO2013149979A1 (en) | 2013-10-10 |
| KR20150003198A (ko) | 2015-01-08 |
| AU2013245105A1 (en) | 2014-10-23 |
| PL2833945T3 (pl) | 2021-03-08 |
| BR112014024651A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2017-06-20 |
| CN104519928B (zh) | 2017-09-22 |
| US20150057619A1 (en) | 2015-02-26 |
| AU2013245105B2 (en) | 2017-10-19 |
| BR112014024651B1 (pt) | 2021-09-21 |
| KR102144138B1 (ko) | 2020-08-12 |
| US9849245B2 (en) | 2017-12-26 |
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