RU2597746C2 - Способы и композиции для лечения вич-ассоциированной диареи - Google Patents

Способы и композиции для лечения вич-ассоциированной диареи Download PDF

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Publication number
RU2597746C2
RU2597746C2 RU2013123794/15A RU2013123794A RU2597746C2 RU 2597746 C2 RU2597746 C2 RU 2597746C2 RU 2013123794/15 A RU2013123794/15 A RU 2013123794/15A RU 2013123794 A RU2013123794 A RU 2013123794A RU 2597746 C2 RU2597746 C2 RU 2597746C2
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crofelemer
administration
per day
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day
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RU2013123794/15A
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English (en)
Russian (ru)
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RU2013123794A (ru
Inventor
Уильям ФОРБС
Инок БОРТИ
Стивен КИНГ
Правин ЧАТУРВЕДИ
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Напо Фармасьютиклз, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45994461&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2597746(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Напо Фармасьютиклз, Инк. filed Critical Напо Фармасьютиклз, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
RU2013123794/15A 2010-10-31 2011-10-31 Способы и композиции для лечения вич-ассоциированной диареи RU2597746C2 (ru)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US40862210P 2010-10-31 2010-10-31
US61/408,622 2010-10-31
US40933510P 2010-11-02 2010-11-02
US61/409,335 2010-11-02
US41624910P 2010-11-22 2010-11-22
US61/416,249 2010-11-22
US201161434379P 2011-01-19 2011-01-19
US61/434,379 2011-01-19
PCT/US2011/058549 WO2012058664A1 (en) 2010-10-31 2011-10-31 Methods and compositions for treating hiv-associated diarrhea

Publications (2)

Publication Number Publication Date
RU2013123794A RU2013123794A (ru) 2014-12-10
RU2597746C2 true RU2597746C2 (ru) 2016-09-20

Family

ID=45994461

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2013123794/15A RU2597746C2 (ru) 2010-10-31 2011-10-31 Способы и композиции для лечения вич-ассоциированной диареи

Country Status (20)

Country Link
US (4) US8962680B2 (cg-RX-API-DMAC7.html)
EP (1) EP2632550B1 (cg-RX-API-DMAC7.html)
JP (2) JP6063385B2 (cg-RX-API-DMAC7.html)
CN (2) CN107595836A (cg-RX-API-DMAC7.html)
AU (1) AU2011320155B2 (cg-RX-API-DMAC7.html)
BR (1) BR112013010774A2 (cg-RX-API-DMAC7.html)
CA (1) CA2816416C (cg-RX-API-DMAC7.html)
DK (1) DK2632550T3 (cg-RX-API-DMAC7.html)
EC (1) ECSP13012650A (cg-RX-API-DMAC7.html)
ES (1) ES2635435T3 (cg-RX-API-DMAC7.html)
HK (1) HK1249036A1 (cg-RX-API-DMAC7.html)
HU (1) HUE035393T2 (cg-RX-API-DMAC7.html)
MX (1) MX348184B (cg-RX-API-DMAC7.html)
PE (1) PE20140036A1 (cg-RX-API-DMAC7.html)
PH (1) PH12013500857A1 (cg-RX-API-DMAC7.html)
PL (1) PL2632550T3 (cg-RX-API-DMAC7.html)
PT (1) PT2632550T (cg-RX-API-DMAC7.html)
RU (1) RU2597746C2 (cg-RX-API-DMAC7.html)
WO (1) WO2012058664A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201303136B (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070254050A1 (en) 2006-05-01 2007-11-01 Quart Barry D Method for treatment of diarrhea-predominant irritable bowel syndrome
EP2015639A4 (en) 2006-05-01 2009-11-25 Napo Pharmaceuticals Inc METHOD FOR TREATING CONSTITUTIONAL PREDOMINANT IRRITATION SYNDROME
WO2007130893A2 (en) * 2006-05-01 2007-11-15 Napo Pharmaceuticals, Inc. Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer
HUE035393T2 (en) 2010-10-31 2018-05-02 Napo Pharmaceuticals Inc Procedures and preparations for the treatment of HIV-related diarrhea
US20140163096A1 (en) * 2012-12-07 2014-06-12 Pam Golden Methods and compositions for treating hiv-associated diarrhea
US11389424B2 (en) 2017-03-09 2022-07-19 Napo Pharmaceuticals, Inc. Methods and compositions for treating chemotherapy-induced diarrhea
JOP20190275A1 (ar) 2017-05-31 2019-11-27 Napo Pharmaceuticals Inc طرق وتركيبات لعلاج اضطراب إسهال خِلقي
JOP20190276A1 (ar) 2017-05-31 2019-11-27 Napo Pharmaceuticals Inc طرق وتركيبات لعلاج إسهال الحمض الصفراوي، والإسهال المرتبط باستئصال الأمعاء الدقيقة أو إزالة المرارة، ومتلازمة الأمعاء القصيرة
EP3935581A4 (en) 2019-03-04 2022-11-30 Iocurrents, Inc. DATA COMPRESSION AND COMMUNICATION USING MACHINE LEARNING
JOP20220339A1 (ar) * 2020-06-19 2023-01-30 Napo Pharmaceuticals Inc طرق وتركيبات علاج الإسهال الناتج عن العلاج الكيميائي
WO2022115481A1 (en) * 2020-11-24 2022-06-02 Napo Pharmaceuticals, Inc. Methods and compositions for treating post-acute infection gastrointestinal disorders

Citations (1)

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US20080025966A1 (en) * 2004-01-30 2008-01-31 Currie Mark G Methods And Compositions For The Treatment Of Gastrointestinal disorders

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US5211944A (en) 1990-10-12 1993-05-18 Shaman Pharmaceuticals, Inc. Proanthocyanidin polymers having antiviral activity and methods of obtaining same
EP2255661A3 (en) 1996-10-16 2010-12-22 Napo Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer antidiarrheal compositions
WO2000047062A2 (en) 1999-02-01 2000-08-17 Shaman Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer dietary supplements and methods for preparing same
US20040071793A1 (en) 2002-10-05 2004-04-15 Bobrowski Paul J. Oral rehydration methods and compositions
EP1937655A1 (en) * 2005-06-22 2008-07-02 University of Massachusetts Hiv-1 protease inhibitors, and methods of making and using them
JP2009524585A (ja) 2005-12-15 2009-07-02 バイエル・ヘルスケア・アクチェンゲゼルシャフト ウイルス感染を処置するためのジアリールウレア
EP2015639A4 (en) * 2006-05-01 2009-11-25 Napo Pharmaceuticals Inc METHOD FOR TREATING CONSTITUTIONAL PREDOMINANT IRRITATION SYNDROME
WO2007130893A2 (en) 2006-05-01 2007-11-15 Napo Pharmaceuticals, Inc. Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer
US20070254050A1 (en) 2006-05-01 2007-11-01 Quart Barry D Method for treatment of diarrhea-predominant irritable bowel syndrome
US20100092479A1 (en) 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US7928115B2 (en) 2008-10-02 2011-04-19 Salix Pharmaceuticals, Ltd. Methods of treating travelers diarrhea and hepatic encephalopathy
PH12012500557A1 (en) 2009-08-26 2012-10-22 Glenmark Pharmaceuticals Ltd Method for producing proanthocyanidin polymer compositions for pharmaceutical formulations
CA2777214A1 (en) * 2009-10-06 2011-04-14 The Regents Of The University Of California Methods of treating diseases with proanthocyanidin oligomers such as crofelemer
US20110087530A1 (en) 2009-10-09 2011-04-14 Visa U.S.A. Inc. Systems and Methods to Provide Loyalty Programs
HUE035393T2 (en) 2010-10-31 2018-05-02 Napo Pharmaceuticals Inc Procedures and preparations for the treatment of HIV-related diarrhea
BR112013018688B1 (pt) 2011-01-27 2021-08-24 Napo Pharmaceuticals, Inc Método de produção de uma composição polimérica de proantocianidina
MX2014007635A (es) 2011-12-22 2014-09-22 Glenmark Pharmaceuticals Ltd Composicion farmaceutica no enterica que comprende crofelemer.
US20140163096A1 (en) 2012-12-07 2014-06-12 Pam Golden Methods and compositions for treating hiv-associated diarrhea

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US20080025966A1 (en) * 2004-01-30 2008-01-31 Currie Mark G Methods And Compositions For The Treatment Of Gastrointestinal disorders

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CRUTCHLEY RD et al. Crofelemer, a novel agent for treatment of secretory diarrhea. Ann Pharmacother.2010 May; 44(5):878-84, реферат, найдено 23.09.2015, найдено из PubMed PMID:20388859. *
HOLODNIY M. et al. A lobule blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS. Am.J.Gastroenterol. 1999 Nov; 94(11):3267-73 *
HOLODNIY M. et al. A lobule blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS. Am.J.Gastroenterol. 1999 Nov; 94(11):3267-73;MANGEL AW et al. ";Evaluation of crofelemer in the treatment of diarrhea-predominant irritable bowel syndrome patients";. Digestion, 2008;78(4):180-6, реферат, найдено 23.09.2015, найдено из PubMed PMID:19092244;CRUTCHLEY RD et al. Crofelemer, a novel agent for treatment of secretory diarrhea. Ann Pharmacother.2010 May; 44(5):878-84, реферат, найдено 23.09.2015, найдено из PubMed PMID:20388859. *
MANGEL AW et al. ";Evaluation of crofelemer in the treatment of diarrhea-predominant irritable bowel syndrome patients";. Digestion, 2008;78(4):180-6, реферат, найдено 23.09.2015, найдено из PubMed PMID:19092244 *

Also Published As

Publication number Publication date
BR112013010774A2 (pt) 2017-03-21
AU2011320155B2 (en) 2016-02-25
CA2816416C (en) 2020-02-11
US8962680B2 (en) 2015-02-24
AU2011320155A1 (en) 2013-05-09
ES2635435T3 (es) 2017-10-03
PL2632550T3 (pl) 2017-10-31
HK1249036A1 (zh) 2018-10-26
PT2632550T (pt) 2017-08-02
MX2013004873A (es) 2013-08-21
EP2632550B1 (en) 2017-05-03
ZA201303136B (en) 2016-01-27
PE20140036A1 (es) 2014-01-31
EP2632550A1 (en) 2013-09-04
ECSP13012650A (es) 2013-10-31
JP6310971B2 (ja) 2018-04-11
US20120184605A1 (en) 2012-07-19
RU2013123794A (ru) 2014-12-10
JP2017019806A (ja) 2017-01-26
WO2012058664A1 (en) 2012-05-03
CA2816416A1 (en) 2012-05-03
PH12013500857A1 (en) 2018-01-17
US20140294903A1 (en) 2014-10-02
JP2013540826A (ja) 2013-11-07
EP2632550A4 (en) 2014-04-23
HUE035393T2 (en) 2018-05-02
US20150190367A1 (en) 2015-07-09
US20120107370A1 (en) 2012-05-03
DK2632550T3 (en) 2017-08-07
JP6063385B2 (ja) 2017-01-18
CN107595836A (zh) 2018-01-19
US9585868B2 (en) 2017-03-07
CN103370101A (zh) 2013-10-23
MX348184B (es) 2017-06-02

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