RU2574362C2 - Method of treating acute pulpitis herbal medicinal product - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly dentistry, and concerns treating acute pulpitis. The method involves giving infiltration anaesthesia, preparing a decay cavity, processing with 3% hydrogen peroxide and applying a herbal medicinal product under a temporary filling to be thereafter replaced by a permanent one. The medicinal product represents an ointment of the following composition: argan oil or sunflower oil - 66.0 gram; yellow wax - 22.0 gram; 70% marigold infusion - 5.0 ml; Japanese sophora infusion - 6.0 ml; ecdysterone - 0.05 gram; clove essence - 1 ml. The ointment is produced as follows. Sunflower or argan oil and yellow wax are heated in a water bath until the wax melts. The produced base is added with marigold infusion 5 ml and sophora infusion 6 ml with pre-dissolved ecdysterone 0.05 gram. The mixture is emulsified thoroughly, added with clove essence 1.0 ml and homogenised.

EFFECT: using produced medicinal product in the method ensures the pronounced reparative, anti-inflammatory, odontotropic action, and preserves these effects over a long period of time.

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Description

The invention relates to medicine, namely to dentistry, and for the treatment of acute pulpitis, which is one of the urgent problems of modern dentistry.

According to recent studies in our country, in the structure of dental morbidity in terms of reversibility, pulpitis takes the second place after caries and amounts to 14-20%.

The inflammatory process in the pulp occurs in response to stimuli coming from the carious cavity, the main ones are microorganisms and their toxins.

Acute inflammation of the tooth pulp is characterized by pulp edema, the appearance of squamous, histiocytic restricted or diffuse, merging into large fields of infiltrates, degeneration of collagen fibers. Fibrin is deposited in the walls of the vessels, their thickness is penetrated by lymphoid-histiocytic elements and fibroblasts, and histiocytic infiltrates along the vessels are visible. There is a disorganization of odontoblasts, in which the characteristic dense arrangement of rows of cells is completely lost. In acute inflammation, the vacuolarization of the cytoplasm of cellular elements is not uniformly expressed.

At the early stages of inflammation, dystrophic changes were observed in almost all pulp fibroblast and histiocyte infrastructures, and the changes were generally reversible.

The activity of enzymes of the redox cycle in the cytoplasm of cell infiltrates and in the cells of the peripheral parts of the coronal pulp is increased, the activity of alkaline phosphatase is increased, especially in the walls of blood vessels. Untimely and poor-quality treatment of acute focal and traumatic pulpitis leads to infection, and subsequently to tooth pulp necrosis. Currently, the functional safety of tooth pulp in the treatment of reversible forms of pulpitis is one of the urgent problems of modern dentistry.

One of the problems of modern therapeutic dentistry is the development of therapeutic drugs that normalize the structure and function of tooth pulp.

Of particular interest are the biomedical and technological qualities of the materials used as medical pads.

Currently, the most common method of preserving pulp viability is to treat it by coating with preparations containing calcium hydroxide. In this case, a repeated change of preparations containing calcium hydroxide is required, which can lead to reinfection and irritation of the pulp. In addition, it was found that when using various preparations containing calcium hydroxide, partial pulp necrosis or a sufficiently pronounced chemical damage was observed, as well as the inferiority of the structure of the dentin bridge formed above it. However, even if it is clearly detected on an x-ray, this calcified formation does not always provide a long and reliable sealing of the tooth pulp.

Thus, according to some authors, the antimicrobial activity, which is explained by the high pH immediately after the application of calcium hydroxide-based preparations in the carious cavity, gradually decreases over time, and the impaired edge adaptation causes tunnel defects, marginal infiltration, and secondary microbial invasion from the tooth cavity. The unsolved problem of suppressing pain as an element of the inflammatory process in the pulp and the lack of a deep reparative effect on the pulp of the tooth.

In accordance with the above, the search for effective agents that have anti-inflammatory, odontotropic, bactericidal and analgesic effects used for the biological method of treating reversible forms of pulpitis continues and is relevant.

Our goal was to develop a method for the treatment of acute pulpitis, which would have a pronounced anti-inflammatory, odontotropic, bactericidal and analgesic effect, was relatively inexpensive, convenient to use, and did not cause undesirable consequences.

The goal is achieved by the fact that the proposed herbal preparation is a tool that includes components that are approved for medical use by the State Register of the Russian Federation, Pharmacopoeia of the Russian Federation, GOST articles, in grams:

Prickly argan oil or sunflower oil - 66.0 grams

Yellow wax - 22.0 grams

70% tincture of calendula - 5.0 ml

Tincture of Japanese Sophora - 6.0 ml

Ecdysterone - 0.05 grams

Clove essential oil - 1.0 ml

Dosages do not exceed permissible norms, the herbal preparation is prepared extemporaneously as follows: 66.0 g of barbed argan oil and 22.0 g of yellow wax were weighed into a porcelain cup and the mixture components were heated in a water bath until the wax melted. 5 ml of tincture of calendula and 6 ml of tincture of Japanese saphora were introduced into the resulting base, in which 0.05 g of ecdysterone was previously dissolved and the mixture was thoroughly emulsified. Then 1.0 ml of clove oil was added and the mixture was homogenized until an ointment was obtained.

This ointment was used in the treatment of acute pulpitis by applying dentin, a paste after infiltration anesthesia with a 2% solution of Ultracaine into a carious cavity under a temporary filling, preparing a carious cavity, drug treatment with a 3% solution of hydrogen peroxide and drying with a weak stream of air and subsequent replacement after 2 months with a temporary Permanent fillings - Charisma, and finishing processing of the seal.

Clinical studies of the proposed method of treatment when using a herbal preparation was carried out at the Department of Therapeutic and Pediatric Dentistry, GBOU VPO Ryazan State Medical University of the Ministry of Health of Russia. 22 patients (including 14 men and 8 women) aged 18 to 40 years were treated. A total of 25 teeth were cured with the following clinical diagnosis: acute pulpitis.

Example 1

Patient A., 28 years old, turned to the Department of Therapeutic and Pediatric Dentistry, GBOU VPO Ryazan State Medical University on 02/04/2012 with complaints of spontaneous, paroxysmal night pain with short pain periods and long inter-pain intervals of pain from a cold tooth 2.7.

Anamnesis of the disease: pain of this nature arose for the first time 1 day ago.

Objectively: on the medial-masticatory surface of the 2.7 tooth, a deep carious cavity made by softened pigmented dentin, not communicating with the tooth cavity. Probing is painful at one point. The reaction to the cold is painful, prolonged, percussion is painless. EDI-21 μA.

Diagnosis: acute pulpitis 2.7.

Treatment: under the infiltration anesthesia of a 2% solution of ultracaine, a cavity was prepared, a drug was treated with a 3% solution of hydrogen peroxide, dried with a weak stream of air, application of a herbal preparation, temporary filling - dentin - paste.

03/04/2012 - no complaints.

Medical history: continues treatment for acute pulpitis 2.7 tooth.

Objectively: the temporary filling is preserved, percussion is painless. EDI - 18 μA.

Treatment: removal of a temporary seal, application of an insulating pad - Fuji 9, permanent seal - charisma, grinding, polishing the seal.

05/05/2012 - no complaints, EDI -16 μA.

6 months after treatment (August 2, 2012), the electric excitability increased and, according to electrodontometry, was 12 μA.

After 12 months (02/06/2013) after the treatment, there were no complaints, the electrodontometry indices decreased and amounted to 10 μA, which indicates the restoration of the tooth pulp structure.

Example 2

Patient M., 31 years old, turned to the Department of Therapeutic and Pediatric Dentistry, GBOU VPO Ryazan State Medical University of the Ministry of Health of Russia on 05.03.2012 with complaints of spontaneous, paroxysmal pain with short pain periods and long pain-free gaps in the tooth 1.8. Pain of this nature appeared for the first time, disturbed during the day.

Objectively: in tooth 1.8 there is a deep carious cavity within the peri-pulp dentine, made by softened light dentin, probing is painful in the area of the projection of the pulp horn, the tooth cavity is not opened. The reaction to cold is painful, prolonged. Percussion is painless.

Diagnosis: acute pulpitis 1.8.

Treatment: under Sol infiltration anesthesia. Ultracaini 2% - 1.7 ml preparation of a carious cavity was carried out, drug treatment with a 3% hydrogen peroxide solution, drying with a weak stream of air, application of a herbal preparation, temporary dentin filling, paste.

04/05/2012 - no complaints.

Anamnesis of the disease - continues treatment for acute pulpitis 1.8 tooth. Objectively: the temporary filling is preserved, percussion is painless. EDI - 20 μA.

Treatment: removal of a temporary seal, application of an insulating pad - Fuji 9, permanent seal - charisma. Grinding, polishing fillings.

06/06/2012 - no complaints. Objectively: a permanent seal is preserved, EDI is 16 μA.

6 months after treatment (September 4, 2012), the electric excitability increased and according to electrodontometry it was 11 μA.

After 12 months (03/09/2013) after treatment, there were no complaints, the values of electrodontometry decreased and amounted to 9 μA.

Thus, the patented method of treating acute pulpitis using the herbal preparation proposed by the authors provides a pronounced reparative, anti-inflammatory, odontotropic and analgesic effect while maintaining this effect for a long time. During the treatment there was not a single case of undesirable complications. The treatment method is convenient to use, physiological, indicates the restoration of the structure of the tooth pulp.

Literature

1. Boykov M.I. An experimental study of the effect of filling materials on the pulp of teeth while eliminating a tooth root defect. / M.I. Boykov // Kremlin medicine. - 2010. - No. 1. - from. 6-11.

2. Sirak S.V. The study of morphological changes in the pulp of the teeth of experimental animals in the treatment of deep caries and acute focal pulpitis / S.V. Syrac, A.G. Syrac, I.A. Kopylova, A.K. Biragova // Medical Bulletin of the North Caucasus. - 2011. - T.23. - Number 3. - S. 29-33.

3. Zoryan E.V. Homeopathic treatment and the possibility of its use in dental practice. Part 1 / E.V. Zoryan, A.V. Zoryan // Clinical. dentistry. - 2002.- No. 3. - S. 48-52.

4. Zoryan E.V. Homeopathic treatment and the possibility of its use in dental practice. Part 2 / E.V. Zoryan, A.V. Zoryan // Clinical. dentistry. - 2002. - No. 4. - S. 46-50.

Claims (1)

A method of treating acute pulpitis with a herbal preparation, including performing an infiltration anesthesia, preparing a cavity, treating with a 3% hydrogen peroxide solution and applying a herbal preparation under a temporary filling, followed by replacing the temporary filling with a permanent one, characterized in that an ointment of the following composition is used as the preparation: oil argania prickly or sunflower oil - 66.0 grams; yellow wax - 22.0 grams; 70% tincture of calendula - 5.0 ml; tincture of Japanese sophora - 6.0 ml; ecdysterone - 0.05 grams; clove essential oil - 1 ml, while the ointment is obtained as follows: sunflower oil or arganium prickly and yellow wax are heated in a water bath until the wax melts, 5 ml of calendula tincture and 6 ml of Japanese saffron tincture are added to the resulting base, in which 0 , 05 g of ecdysterone, the mixture is thoroughly emulsified, after which 1.0 ml of clove oil is added and the mixture is homogenized.