RU2538629C1 - Method of treating tonsillopharyngitis in children - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: treating tonsillopharyngitis in children is ensured by Panavir Inlight spray gel 1 oropharyngeal irrigation 2 times a day after meal daily for 5 days.

EFFECT: method enables treating more effectively by the anti-viral and cytoprotective action of the preparation, reducing a toxic load with no complications and applicability.

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Description

The invention relates to medicine, namely to infectious diseases in children, can be used to treat tonsillopharyngitis caused by bacteria of the genus Haemophilus (hereinafter referred to as hemophilia), and the carrier of hemophilia, the prevention of frequent respiratory diseases in children and the prevention of respiratory morbidity in kindergartens.

Bacteria of the genus Haemophilus belong to the family Pasteurellaceae. Bacteria are gram-negative pleomorphic bacilli or coccoid cells, which in smears are located singly or in pairs, sometimes in the form of short chains and groups. They are motionless, do not form spores, have a capsule. The causative agent produces endotoxin, the carrier of which are capsular polysaccharides. Hemophiles are aerobes or facultative anaerobes. Microbes are demanding on cultivation conditions. For their growth, media containing blood (chocolate agar) are needed, with the addition of thermolabile factor V and thermostable factor X in red blood cells, the optimum temperature is 37 ° C. In the genus Haemophilus, 16 species of bacteria are distinguished.

Hemophils cause purulent-septic diseases (hemophilesis): meningitis, pneumonia, septicemia, epiglottitis, otitis media, sinusitis, mastoiditis, respiratory diseases, cellulitis, arthritis, osteomyelitis, conjunctivitis, pericarditis, etc.

Features of children's immunity determine the inability of the child's body up to 5 years of age to develop its own antibodies against hemophilic infection. Therefore, the prevalence of hemophilic bacteria in children's groups is from 20 to 70% of children under 5 years old, in 50-60% of children over 5 years old, in 20-40% of adults, which undoubtedly contributes to the formation of frequent and long-term morbidity of children. Mild forms of hemophilic infection are not recognized in a timely manner, children attend preschool educational institutions and are a source of infection for other children. Hemophilic tonsillopharyngitis is characterized by flushing of the tonsils, palatine arches and posterior pharyngeal wall, and the absence of purulent deposits. Only local changes in the mucous membrane of the oropharynx were detected, general manifestations of the disease were not observed, body temperature was normal.

There is a method of treating hemophilic nasopharyngitis with prescription of antibiotics (ampicillin, amoxicillin / clavunate, azithromycin, cephalosporins) (V.F. Uchaykin, N.I. Nisevich, O.V. Shamsheva Infectious diseases and vaccine prevention in children: textbook. M .: GEOTAR - Media, 2007; Infectious Diseases in Children, Edited by D. Murray, Translated from English - M., Praktika, 2006. P. 235). The disadvantages of this method are the development of allergic reactions, complications, dysbiosis, the formation of antibiotic resistance.

Effect: increase the effectiveness of the method of treatment of hemophilic tonsillopharyngitis, prevention of complications of respiratory infections.

These tasks are achieved by using the Panavir preparation in the form of the Panavir Inlight Spray gel, by 1 oropharynx irrigation 2 times a day for 5 days. Panavir is the original domestic herbal medicine (Russia, Moscow Region, Dmitrov, Green Dubrava CJSC). It is a purified extract from potato shoots (Solanum tuberosum, Solanum tuberosum). The composition of the drug - polyethylene glycol, lanthanum salts, biologically active heteroglycoside and water. It does not contain alcohol, dyes, aromatic and hormonal substances, has a neutral pH. Gel “Spray Panavir Inlight” (Russia, Moscow region, Dmitrov. ZAO “Green Dubrava”) has no contraindications for use in children.

The main active ingredient is hexose glycoside, consisting of glucose, rhamnose, arabinose, mannose, xylose, galactose, uronic acids. Due to the biologically active heteroglycoside content, Panavir Inlight Spray Gel has an antiviral bactericidal, immunomodulating, anti-inflammatory, regenerating and protective effect.

Gel “Spray Panavir Inlight” prevents the penetration of viruses into cells, blocks the replication of viral proteins, thereby violating the reproduction of the virus. It has an antiviral effect against DNA and RNA-containing viruses: herpes types I and II, cytomegaloviruses, Epstein-Barr virus, hepatitis C, influenza, tick-borne encephalitis, rabies, human papilloma, adenoviruses and bacteria. Due to its antiviral activity, Spray Panavir Inlight gel significantly reduces the toxic load and has a cytoprotective effect, protecting cells from the effects of viruses.

The protective effect of the Panavir Inlight Spray gel is determined by the unique buffer base, which contains complex compounds of lanthanum. After application, the gel is localized in the middle layers of the mucous membrane and forms a molecular network with selective bandwidth. It retains viruses, bacteria, fungi and macromolecular compounds, but freely passes water, oxygen and nitrogen molecules, providing normal hydration and gas exchange of the mucous membranes.

Anti-inflammatory effect is combined with a stimulating effect on humoral and cellular factors of immunity, induction of the production of interferons. The buffer base blocks the spread of inflammatory factors and the spread of toxic substances.

The regenerating effect is due to an improvement in the restoration of superficial mucosal cells.

Panavir has not been previously used to treat hemophilic tonsillopharyngitis.

The method is as follows: the child is irrigated the oropharynx with Span Panavir Inlight gel from the bottom up, tilting his head over the bottle, after eating 2 times a day for 5 days, daily.

Case Studies

Example 1. Kholev Amirkhamza, 5 years old, attends a kindergarten sanatorium group. In the first year of life, he suffered pneumonia, at the age of 1 year - obstructive bronchitis, has acute respiratory infections 5 times a year. Vaccinated according to the national vaccination schedule. When viewed in the throat, congestion of the tonsils, hypertrophy of the tonsils of the 1st degree and the posterior pharyngeal wall are determined. Bacteriological examination of a swab from the oropharynx: isolated Haemophilus influenzae 10 ⁴ . Diagnosis: Hemophilic tonsillopharyngitis, mild, subacute course. The gel was treated with “Spray Panavir Inlight” gel: irrigation of the oropharynx 2 times a day for 5 days. After treatment, the mucous membranes of the oropharynx and nose of the physiological color, the size of the tonsils decreased. Examination of smears from the oropharynx and nose 2 days after the end of treatment - no bacteria of the genus Haemophilus were found. Recovered recovery.

Example 2. Danil Pazdnikov, 6 years old, attends a kindergarten sanatorium group. She suffers from acute respiratory infections 4-6 times a year, atopic dermatitis, in the first year of life - febrile convulsions. Vaccinated in accordance with the national calendar of preventive vaccinations and against tick-borne encephalitis. When viewed in the throat, hyperemia of the tonsils and palatine arches is determined. Bacteriological examination of a nasal swab: isolated Haemophilus influenzae 10 ³ . Diagnosis: Hemophilic tonsillopharyngitis, mild, subacute course. The gel was treated with “Spray Panavir Inlight” gel: irrigation of the oropharynx 2 times a day for 5 days. After treatment, the mucous membranes of the oropharynx and nose are physiological in color. Examination of smears from the oropharynx and nose 2 days after the end of treatment - no bacteria of the genus Haemophilus were found. Recovered recovery.

Example 3. Masha Usacheva, 4 years old, suffers from Atopic dermatitis, attends a kindergarten sanatorium group. Vaccinated according to the national calendar. When viewed in the throat, hyperemia of the tonsils and posterior pharyngeal wall is determined. Bacteriological examination of a swab from the oropharynx: Haemophilus parainfluenzae 10 ⁴ isolated, Haemophilus parainfluenzae 10 ³ isolated from the nose. Diagnosis: Hemophilic tonsillopharyngitis, mild, subacute course. The gel was treated with “Spray Panavir Inlight” gel: irrigation of the oropharynx 2 times a day for 5 days. After treatment, the mucous membranes of the oropharynx and nose are physiological in color. Examination of smears from the oropharynx and nose 2 days after the end of treatment - no bacteria of the genus Haemophilus were found. Recovered recovery.

Example 4. Luzin Danil, 3 g. 11 months. In kindergarten he visits a sanatorium group for children with allergic dermatoses. Vaccinated according to the national calendar, in January 2012 and in February 2013 - against influenza. He suffers from acute respiratory infections 3-4 times a year, over the past 4 months he has twice suffered an acute respiratory infection. When viewed in the throat, hyperemia of the tonsils is determined. Bacteriological examination of a swab from the oropharynx: Haemophilus paragallinarum 10 ⁴ isolated, Haemophilus paragallinarum 10 ³ isolated from the nose. Diagnosis: Hemophilic tonsillopharyngitis, mild, subacute course. The gel was treated with “Spray Panavir Inlight” gel: irrigation of the oropharynx 2 times a day for 5 days. After treatment, the mucous membranes of the oropharynx and nose are physiological in color. Examination of smears from the oropharynx and nose 2 days after the end of treatment - no bacteria of the genus Haemophilus were found. Recovered recovery.

The positive effect of the proposed method in the form of recovery is that in children hyperemia of the mucous membrane of the oropharynx disappears, nasal breathing improves, the size of the tonsils decreases, health, sleep, appetite as a result of the bactericidal action of Panavir, the oropharynx biocenosis improves, the release of hemophiles from smears stops.

The value of the proposed method lies in the fact that it does not cause complications and adverse reactions, the therapy is not systemic in nature, the treatment is carried out locally, not laborious, cost-effective, and is available for use in children's groups. The method is simple, affordable, easily reproducible, economical, well tolerated by children.

Claims (1)

A method of treating tonsillopharyngitis in children with a medication, characterized in that the spray Panavir Inlight gel is prescribed as a medication, 1 oropharynx irrigation 2 times a day after meals, 5 days, daily.