RU2535778C2 - Устройство доставки адгезива - Google Patents
Устройство доставки адгезива Download PDFInfo
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- RU2535778C2 RU2535778C2 RU2011151632/14A RU2011151632A RU2535778C2 RU 2535778 C2 RU2535778 C2 RU 2535778C2 RU 2011151632/14 A RU2011151632/14 A RU 2011151632/14A RU 2011151632 A RU2011151632 A RU 2011151632A RU 2535778 C2 RU2535778 C2 RU 2535778C2
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Images
Classifications
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- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
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- A—HUMAN NECESSITIES
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- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
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- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
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- G—PHYSICS
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- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/12—Pressure infusion
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Primary Health Care (AREA)
- Surgical Instruments (AREA)
- Coating Apparatus (AREA)
- Materials For Medical Uses (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17963209P | 2009-05-19 | 2009-05-19 | |
| US61/179,632 | 2009-05-19 | ||
| PCT/US2010/035452 WO2010135457A2 (en) | 2009-05-19 | 2010-05-19 | Device for delivering adhesive |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2011151632A RU2011151632A (ru) | 2013-06-27 |
| RU2535778C2 true RU2535778C2 (ru) | 2014-12-20 |
Family
ID=43126755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011151632/14A RU2535778C2 (ru) | 2009-05-19 | 2010-05-19 | Устройство доставки адгезива |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8950629B2 (enExample) |
| EP (1) | EP2432399B1 (enExample) |
| JP (1) | JP5788383B2 (enExample) |
| KR (1) | KR101803981B1 (enExample) |
| CN (1) | CN102612346B (enExample) |
| AU (1) | AU2010249582B2 (enExample) |
| CA (1) | CA2762772C (enExample) |
| IL (1) | IL216461A (enExample) |
| MX (1) | MX357123B (enExample) |
| NZ (1) | NZ596969A (enExample) |
| RU (1) | RU2535778C2 (enExample) |
| WO (1) | WO2010135457A2 (enExample) |
| ZA (1) | ZA201109314B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8985402B2 (en) * | 2009-03-17 | 2015-03-24 | Mark C. Schneider | Cove base nozzle for dispensing applications |
| US8448609B2 (en) * | 2010-01-08 | 2013-05-28 | Ritchey Manufacturing Company | Animal restraint device and method |
| USD697677S1 (en) | 2010-01-08 | 2014-01-14 | Grant A. RITCHEY | Animal restraint |
| WO2012170700A2 (en) * | 2011-06-07 | 2012-12-13 | Orthocon, Inc. | Applicator with conformable tip |
| CN104470429B (zh) | 2012-05-11 | 2018-07-10 | 哈曼国际工业有限公司 | 具有生理传感器的耳机和耳塞 |
| US9266141B2 (en) | 2013-09-10 | 2016-02-23 | Awi Licensing Company | System for applying a coating to a workpiece |
| US11951509B2 (en) | 2013-09-10 | 2024-04-09 | Awi Licensing Llc | System for applying a coating to a workpiece |
| PL3231518T3 (pl) * | 2016-04-15 | 2024-03-25 | Jowat Se | Korpus kleju topliwego w kształcie pręta do pistoletów do kleju topliwego |
| US12089893B2 (en) | 2018-07-19 | 2024-09-17 | Sanulus Medical, LLC | Devices and methods for targeted delivery of a substance |
| KR102850290B1 (ko) | 2018-07-19 | 2025-08-25 | 사눌러스 메디칼, 엘엘씨 | 물질의 타겟화된 전달을 위한 디바이스 및 방법 |
| CN110984536B (zh) * | 2020-01-01 | 2021-02-19 | 刘瑞瑞 | 一种建筑用墙缝封胶器 |
| CN112843404A (zh) * | 2020-12-30 | 2021-05-28 | 武汉维斯第医用科技股份有限公司 | 间歇定量高粘度生物制剂喷涂枪 |
| AU2022398924A1 (en) * | 2021-11-23 | 2024-06-27 | Wobbleworks, Inc. | Hand-held three-dimensional drawing device |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2078584C1 (ru) * | 1992-01-22 | 1997-05-10 | Каби Фармациа АБ | Устройство для раздачи лекарства |
| US20040230157A1 (en) * | 2003-05-16 | 2004-11-18 | Perry Stephen J. | Fluid delivery system and related methods of use |
| US20050173019A1 (en) * | 2004-02-11 | 2005-08-11 | Navarro Ramon M. | Apparatus for the simultaenous filling of precise amounts of viscous liquid material in a sanitary environment |
| US20060111738A1 (en) * | 2004-10-18 | 2006-05-25 | Thomas Wenchell | Apparatus for applying wound treatment material using tissue-penetrating needles |
| WO2007122006A1 (en) * | 2006-04-26 | 2007-11-01 | Summit Medical Limited | A medical treatment material delivery apparatus |
| US20080103564A1 (en) * | 2005-08-17 | 2008-05-01 | Burkinshaw Brian D | Method for repairing intervertebral discs |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2725877A (en) * | 1950-12-22 | 1955-12-06 | Reiter David | Hypodermic syringe with feed control |
| US2792003A (en) * | 1955-12-27 | 1957-05-14 | Edward B Cantor | Vaginal medicament applicators |
| US4099482A (en) * | 1977-05-11 | 1978-07-11 | Smrt Thomas John | Marking apparatus with measuring device |
| SU1516117A1 (ru) | 1987-07-13 | 1989-10-23 | Ш. М. Камалов | Устройство дл анестезии |
| US5441583A (en) * | 1992-02-13 | 1995-08-15 | Insta-Foam Products, Inc. | Method of use of multiple adhesive foam bead applicator |
| US5503302A (en) * | 1995-01-25 | 1996-04-02 | Primary Delivery Systems, Inc. | Sealed container puncturer and spray dispensing device |
| US5735437A (en) * | 1996-01-22 | 1998-04-07 | Minnesota Mining And Manufacturing | Lockable, hand-held dispenser and mixing tray for dispensing small quantities of material |
| US5875920A (en) * | 1996-07-29 | 1999-03-02 | Parent; Rodger G. | Caulking Gun |
| US5882133A (en) * | 1996-11-01 | 1999-03-16 | Premark Rwp Holdings, Inc. | Glue applicator for laminate flooring |
| AU750676B2 (en) | 1997-10-07 | 2002-07-25 | Baxter International Inc. | Controlled action, manually operable fluid applicator |
| US6024250A (en) * | 1998-01-26 | 2000-02-15 | Hickey; Patrick J. | Tip sealing system for non-contact glue applicator |
| GB0024734D0 (en) | 2000-10-10 | 2000-11-22 | Briggs Darren | Fluent material applicator |
| SE0100091D0 (sv) | 2001-01-12 | 2001-01-12 | Pharmacia Ab | A device and a method for dispensing at least two mutually reactive components |
| US20020173770A1 (en) * | 2001-05-16 | 2002-11-21 | Flory Alan R. | Adhesive delivery system |
| GB0312974D0 (en) * | 2003-06-06 | 2003-07-09 | Spencer Alan | Dispensing apparatus and a dispensing nozzle for use therewith |
| US6981611B2 (en) * | 2003-09-09 | 2006-01-03 | Ronald Scott Carruth | Tip for a caulking gun |
| GB2410909A (en) | 2004-02-10 | 2005-08-17 | Stephen David Richards | Adhesive applicator |
| US7748920B2 (en) * | 2004-07-21 | 2010-07-06 | Murray John W | Multiple tuckpointing tool and method disclosure |
| US8104642B2 (en) * | 2004-08-31 | 2012-01-31 | Quikshot Packaging Pty Ltd | Beverage dispenser and method |
| GB0621663D0 (en) | 2006-10-27 | 2006-12-06 | Oliver Baden | Tile adhesive applicator |
| WO2008091561A1 (en) * | 2007-01-22 | 2008-07-31 | Cvdevices, Llc | Endovascular periaortic magnetic glue delivery |
| US8790366B2 (en) * | 2007-11-13 | 2014-07-29 | Alcon Research, Ltd. | Fan-shaped cannula for sealing ophthalmic incisions |
| US20100237104A1 (en) * | 2009-03-17 | 2010-09-23 | Schneider Mark C | Cove Base Nozzle for Dispensing Applications |
-
2010
- 2010-05-19 CN CN201080033850.1A patent/CN102612346B/zh not_active Expired - Fee Related
- 2010-05-19 CA CA2762772A patent/CA2762772C/en not_active Expired - Fee Related
- 2010-05-19 NZ NZ596969A patent/NZ596969A/en not_active IP Right Cessation
- 2010-05-19 KR KR1020117030255A patent/KR101803981B1/ko active Active
- 2010-05-19 JP JP2012512001A patent/JP5788383B2/ja active Active
- 2010-05-19 RU RU2011151632/14A patent/RU2535778C2/ru not_active IP Right Cessation
- 2010-05-19 WO PCT/US2010/035452 patent/WO2010135457A2/en not_active Ceased
- 2010-05-19 US US12/783,378 patent/US8950629B2/en active Active
- 2010-05-19 EP EP10778348.2A patent/EP2432399B1/en not_active Not-in-force
- 2010-05-19 MX MX2011012304A patent/MX357123B/es active IP Right Grant
- 2010-05-19 AU AU2010249582A patent/AU2010249582B2/en not_active Ceased
-
2011
- 2011-11-17 IL IL216461A patent/IL216461A/en not_active IP Right Cessation
- 2011-12-19 ZA ZA2011/09314A patent/ZA201109314B/en unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2078584C1 (ru) * | 1992-01-22 | 1997-05-10 | Каби Фармациа АБ | Устройство для раздачи лекарства |
| US20040230157A1 (en) * | 2003-05-16 | 2004-11-18 | Perry Stephen J. | Fluid delivery system and related methods of use |
| US20050173019A1 (en) * | 2004-02-11 | 2005-08-11 | Navarro Ramon M. | Apparatus for the simultaenous filling of precise amounts of viscous liquid material in a sanitary environment |
| US20060111738A1 (en) * | 2004-10-18 | 2006-05-25 | Thomas Wenchell | Apparatus for applying wound treatment material using tissue-penetrating needles |
| US20080103564A1 (en) * | 2005-08-17 | 2008-05-01 | Burkinshaw Brian D | Method for repairing intervertebral discs |
| WO2007122006A1 (en) * | 2006-04-26 | 2007-11-01 | Summit Medical Limited | A medical treatment material delivery apparatus |
Also Published As
| Publication number | Publication date |
|---|---|
| US20110062189A1 (en) | 2011-03-17 |
| ZA201109314B (en) | 2013-02-27 |
| AU2010249582A1 (en) | 2011-12-15 |
| MX357123B (es) | 2018-06-27 |
| AU2010249582B2 (en) | 2015-02-12 |
| RU2011151632A (ru) | 2013-06-27 |
| JP5788383B2 (ja) | 2015-09-30 |
| CA2762772C (en) | 2017-10-24 |
| EP2432399A2 (en) | 2012-03-28 |
| WO2010135457A2 (en) | 2010-11-25 |
| MX2011012304A (es) | 2012-05-08 |
| KR101803981B1 (ko) | 2017-12-01 |
| KR20120090012A (ko) | 2012-08-16 |
| CN102612346B (zh) | 2015-06-17 |
| NZ596969A (en) | 2014-04-30 |
| EP2432399A4 (en) | 2015-03-04 |
| IL216461A0 (en) | 2012-01-31 |
| US8950629B2 (en) | 2015-02-10 |
| CA2762772A1 (en) | 2010-11-25 |
| CN102612346A (zh) | 2012-07-25 |
| JP2012527323A (ja) | 2012-11-08 |
| AU2010249582A2 (en) | 2011-12-15 |
| IL216461A (en) | 2014-02-27 |
| HK1174237A1 (en) | 2013-06-07 |
| WO2010135457A3 (en) | 2011-04-21 |
| EP2432399B1 (en) | 2018-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20190520 |