RU2432947C1 - Preparation for controlling bird ectoparasites - Google Patents

Abstract

FIELD: medicine. ^ SUBSTANCE: invention relates to veterinary. Preparation for controlling bird ectoparasites contains active substances, as such used is neonol and soya phosphatides with the following component ratio, wt %: neonol - 0.1-0.5; soya phosphatides - 0.1-0.5; water - the remaining part. ^ EFFECT: preparation makes it possible to eliminate parasites completely by one processing, is not toxic, does not irritate animal's skin, is harmless for animals and environment, its application does not have limitations for lactating animals, young animals and for application of milk and meat, obtained after preparation application.

Description

The invention relates to the field of veterinary medicine, in particular to the prevention and treatment of diseases caused by ectoparasites of animals, and can be used to protect cattle from ixodid ticks.

It is known to use an effective drug neostomozan for controlling ectoparasites of animals, which is a concentrated preparation containing photostable pyrethroids (transimix, tetramethrin), as well as auxiliary substances and stabilizers. Neostomozan has a wide spectrum of action for the treatment of animals (see "Modern antiparasitic drugs in veterinary medicine.” Textbook for high schools. / Bespalova NS - M.: Kolos Publishing House, 2006, pp. 83-84).

A disadvantage of the known drug is that for complete cure, multiple treatments are required, which is associated with additional labor costs and significant drug costs. The drugs have a toxic effect, therefore, after processing the animals, their meat can be eaten no earlier than a month later.

The closest in technical essence is a preparation for combating ectoparasites of animals, containing active substances or a mixture thereof, including neonol, a plasticizer or a mixture thereof, a film-forming substance or a mixture thereof, a repellent or a mixture thereof, an antiseptic or a mixture thereof, an organic solvent or a mixture thereof ( see RF patent No. 2072843 for IPC A01N 25/00, publ. 02/10/1997). Known drugs for combating ectoparasites of animals are expensive, require additional labor and drug consumption due to the need for multiple treatments in order to achieve a positive effect for complete cure.

The drugs have toxic effects and have limitations on its use for lactating animals (dairy cows) and on young animals.

The technical result of the invention is to increase the effectiveness of the drug, increase its stability, shelf life, reduce costs and treatment time of animals.

The problem is solved in order to achieve a technical result by the fact that in the preparation for combating ectoparasites containing active substances and water, according to the invention, neonol and soy phosphatides are used as active substances, in the following ratio of components, wt.%: Neonol - 0.1- 0.5; soybean phosphatides - 0.1-0.5; water is the rest.

The boundary values of the constituent components of the drug were determined experimentally.

The manufacture of the proposed drug and its use is illustrated by the example of a specific implementation.

At the first stage, a preparation concentrate is prepared, and then the proposed preparation itself is prepared in the form of a working solution in water. To obtain the concentrate of the proposed drug, 200 g of soybean phosphatides are added to 200 g of neonol, placed in the capacity of the tissue grinder RT-1, and after stirring for 40 minutes, a yellow creamy mass is obtained - the drug concentrate. Get the proposed drug in the form of a liquid creamy mass (drug concentrate). To obtain a working solution, water is added to the obtained concentrate of the preparation. To obtain the proposed drug in the form of a working solution, the volume of the concentrate is adjusted to 10 l and a 4% solution is obtained, which is used to process animals.

To obtain the proposed drug in the form of a working solution, the drug concentrate is diluted with water to the percentage of ingredients: neonol - 0.1% and soy phosphatides - 0.1%, water - the rest. To do this, calculate according to the well-known formula

where X is the required amount of drug concentrate for diluting neonol to a concentration of 0.1%;

A - the amount of neonol in concentrate as a percentage;

B - the required concentration of neonol for the working solution in percent.

After calculation, the amount of the drug concentrate required for diluting neonol to 0.1% is 2 ml. 998 ml of water is added to a 2 ml concentrate of the preparation.

Thus, a working solution of the proposed preparation is obtained with a concentration of neonol - 0.1% and soy phosphatides - 0.1% for treating animals against exoparasites.

The calculation of the required amount of water to be added to the concentrate of the preparation is done using the neonode ingredient. The claims indicate the concentrations of constituent substances that give the highest effect against animal exoparasites.

A test of the effectiveness of the systemic effects of the proposed drug.

To test the drug, fifteen calves weighing 60 ± 5 kg infected with ixodid mites were selected. Gobies were divided into five groups of 3 bulls.

The presence of ixodid ticks was determined by visual inspection. Before treatment, the number of ticks varied from 5 to 10 copies per head.

The experimental procedure for the destruction of ixodid ticks in cattle consisted in watering animals along the spinal column and spraying from a backpack sprayer until the hairline of the animals was completely wetted.

A working solution of the drug with a different ratio of components, including beyond the boundary values, was applied to individual groups of animals once.

The effectiveness of the treatments and accounting for the death of ticks was determined after 24 hours by counting the living and the dead directly on animals.

Experimental studies have shown that compositions in which the active substances correspond to the proposed limits of the boundary values of the ratio of the components give a 100% recovery effect, since only dead ticks were found a day after treatment. Side effects in animals were not observed. The composition that differs in composition from the proposed boundary values of the ratio of components does not cause recovery in the test groups. The residual effect of the drug ranged from 25 to 30 days.

The proposed drug can significantly reduce treatment time. When treating with the proposed drug, there is no need to re-treat the animals. The drug is non-toxic, does not irritate the skin of the animal, is harmless to animals and the environment, its use has no restrictions on lactating animals, young animals and the use of milk and meat.

Claims (1)

A preparation for combating ectoparasites of animals, containing active substances and water, characterized in that neonol and soy phosphatides are used as active substances in the following ratio of components, wt.%:
neonol 0.1-0.5 soya phosphatides 0.1-0.5 water rest