RU2400214C1 - Healing and regenerative skin care product - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to cosmetic industry, namely to preparation of a healing and regenerative skin care product containing beeswax, sea-buckthorn oil, an calendula oil extract, propolis extract, characterised by the fact that in addition contains lavender essence, tea tree essence, rosemary essence, terpentine oil, purple Echinacea oil extract, vitamin E, vitamin A and lactic lipids.

EFFECT: product is used for cutting time of small wounds and inflammation healing, cutting time of skin texture topography, better penetration effect in human tissues, enhanced transepidermal dehydration, longer storage time.

6 ex

Description

The invention relates to the cosmetic industry, namely to the production of cosmetic balm creams, and can be used both in cosmetic and for therapeutic purposes as a healing agent that effectively restores the functional activity of receptors and cell membranes, which has a bactericidal, antiseptic and regenerative effect.

The deterioration of the ecological situation and the violation of traditional nutrition led to a violation of the functional purpose of the skin due to a violation of the hydrolipidic balance, the appearance of microtraumas and foci of inflammation. Such violations required the expansion of the functionality of balsam creams in the direction of enhancing their antiseptic and wound healing capabilities, allowing skin cells to regenerate.

So, from a previous level, a cosmetic cream-balm for face and neck skin care is known, containing vegetable oils, mummy, sea buckthorn oil, peppermint oil, soybean, as well as calendula extract, plantain extract, vitamin E, vitamin A, beeswax, emulsion wax , stearate, glycerin, alcohols C16-C20, PEG-400 oleate, lanolin, hyaluronic acid and preservatives in the form of methyl paraben, propyl paraben, kemaben 2E, reokart. The following biologically active ingredients are common ingredients with the ingredients of the claimed invention: sea buckthorn oil, calendula extract, vitamin E, vitamin A and beeswax.

The sea-buckthorn oil included in the composition of the balm composition in terms of biologically active substances is unparalleled in a number of vegetable oils and includes more than one hundred healing substances, including vitamins, as well as palmitoleic acid, which is rare in the plant world, which stimulates the processes of skin respiration and blood circulation, strengthens and improves the quality of healing of microtraumas on the skin and promotes restoration processes in damaged tissues. Sea buckthorn oil has anti-inflammatory, analgesic, wound healing and antimicrobial effects. Calendula extract is an antiseptic and stimulates skin regeneration after burns. Vitamin E is an antioxidant and protects fatty acids, especially unsaturated ones, from oxidation by free radicals. Vitamin A has a stimulating and regenerating effect. Beeswax is a structure-forming component, and also has anti-inflammatory and antimicrobial properties. The composition of beeswax includes esters, free fatty acids, alcohols, paraffin carbohydrates, as well as plant pigments, mineral and aromatic substances and water. Beeswax in the presence of triglycerides is able to release oxygen, which contributes to a moderate bactericidal effect and tissue healing.

The well-known cream-balm due to the combination of biologically active substances in its composition in a certain ratio of ingredients has an antiseptic, decongestant, anti-aging and strengthening effect and can be used as a therapeutic and prophylactic agent for skin care, including damaged and aging, but is most effective when caring for face and neck skin [Patent RU for the invention No. 2314791, date publ. 01/20/2008].

One of the disadvantages of the known balm is the insufficient degree of penetration of biologically active substances into biological tissues, as a result of which it is not possible to fully use the potential inherent in the composition and, accordingly, compensate for the deficiency of the natural moisture-retaining factor in the intercellular environment of the dermis and achieve enhanced protective properties of the epidermal skin barrier. In addition, the use of C16-C20 alcohols and preservatives in the balm can cause skin irritation and allergic reactions.

Closest to the claimed invention and selected as a prototype for the combination of essential features and achievable technical results is a cosmetic product for skin care with a healing effect [Patent RU for invention No. 2211026, date publ. 08/27/2003]. The cosmetic product includes a fatty ingredient, sea buckthorn oil, cedar oil, rosehip oil, oil extracts of plant materials in the form of perforated hypericum, peony root, incense root, calamus root, chamomile flowers, marigold flowers and thyme herbs, as well as oil propolis extract, “egg oil ”and beeswax. As a fat ingredient used sunflower oil. The above ingredients are contained in the composition of the tool in the following ratio of ingredients, wt.%:

Sea buckthorn oil 0.55-0.58 Cedar oil 0.50-0.53 Rosehip oil 0.65-0.68 Oil extracts of plant materials: Hypericum perforatum 0.80-0.84 Peony root 0.68-0.71 Root Badan 0.46-0.48 Calamus root 0.71-0.75 Chamomile flowers 1,50-1,58 Calendula flower 1.10-1.16 Thyme Herbs 0.50-0.53 Propolis extract 0.03-0.032 "Egg butter" 0.02-0.021 Beeswax 0.96-1.008 Sunflower oil Rest

Common ingredients with the ingredients of the claimed invention are the following biologically active ingredients: sea buckthorn oil, calendula extract, beeswax and oil propolis extract.

Propolis includes biologically active substances with antiviral, anti-inflammatory, anesthetic and biostimulating effects, and is organically combined with other ingredients of the composition.

The well-known cosmetic product for skin care with a healing and regenerating effect is characterized by high vitamin activity, anti-inflammatory, healing and regenerating effects.

Its disadvantages include the liquid consistency of the product, insufficient penetrating ability in biological tissues, insufficient enhancement of skin barrier functions and insufficient prevention of transepidermal moisture loss, which leads to a more rapid deterioration in the topography of the skin texture.

A significant disadvantage of the prototype is the use as a fatty ingredient in the composition of vegetable oil, including a significant amount of unsaturated fatty acids, which reduce the therapeutic result due to the consumption of active ingredients to protect the base from oxidation.

The objective of the invention is to expand the arsenal of well-known cosmetic products for skin care with a healing and regenerating effect of a new more active tool.

Technical results that can be obtained using the claimed invention are:

- the implementation of the appointment of a new cosmetic for skin care with a healing and regenerating effect;

- reduction in the healing time of small wounds and foci of inflammation;

- reduction of time to improve the topography of the skin texture;

- increased penetration in biological tissue;

- reduction of transepidermal moisture loss;

- increase the shelf life.

The solution of this problem and the achievement of the above technical results became possible due to the fact that the well-known cosmetic for skin care with a healing and regenerating effect, containing beeswax, sea buckthorn oil, calendula oil extract, propolis extract, additionally contains lavender essential oil, tea essential oil wood, rosemary essential oil, turpentine oil, echinacea purpurea oil extract, vitamin E, vitamin A and milk lipids, with the following contents NTV, wt.%:

Sea buckthorn oil 3.37-4.12 Lavender essential oil 0.45-0.55 Tea Tree Essential Oil 0.09-0.11 Rosemary essential oil 0.45-0.55 Turpentine oil 2.7-3.3 Echinacea purpurea oil extract 2.7-3.3 Marigold oil extract 2.7-3.3 Propolis extract 0.009-0.011 Vitamin E 0,054-0,066 Vitamin A 0.09-0.11 Beeswax 2,277-2,783 Milk lipids Rest

Unlike the prototype, the claimed cosmetic product for skin care with a healing and regenerating effect includes only one vegetable oil - sea buckthorn oil, but taken in an amount significantly exceeding the total amount of sea buckthorn oil, rosehip oil and cedar oil included in the prototype tool . At the same time, as part of the claimed product, sea buckthorn oil occupies a dominant position and is aimed at healing, restoring skin balance, stimulating skin respiration and blood circulation processes and regeneration. The remaining ingredients are organically combined with the compositional components of sea buckthorn oil and are aimed at synergistic interaction.

Strengthening the composition of cosmetic products with a combination of essential oils in the form of lavender, tea tree and rosemary synergistically increased the antiseptic ability of sea buckthorn oil and expanded the range of its capabilities both due to the properties of each of them separately, and due to the mutual strengthening of the action of the substances contained in them. So, lavender essential oil is one of the best tools for treating skin diseases of various etiologies, including those of nervous origin. The active constituents included in the composition of the oil actively influence various processes occurring in biological tissues. In addition, lavender essential oil is a good analgesic, has strong antiseptic and antimicrobial properties, kills many bacteria, especially streptococci and Staphylococcus aureus, as well as many viruses. Tea tree essential oil has antiviral, antibacterial and antifungal properties. According to antiseptic activity, it is 100 times stronger than carbolic acid with absolute harmlessness to humans. Tea tree essential oil has been successfully used for colds, gum disease, treatment of wounds and acne, for fungal infections of the feet and nails, as well as herpes. Rosemary essential oil has antispasmodic, antiseptic and tonic properties, is widely used for skin care, eliminates inflammatory processes, and, most importantly, improves blood circulation and cell renewal.

The introduction of turpentine oil into the composition of the product, the main part of which is pinene, is synergistic with propolis, which diffuses well in the tissue, enhances the transport of active substances through the epidermis. In addition, pinene causes reflex changes in the body as a result of irritation of the skin receptors, and propolis activates the activity of protective factors and increases the body's resistance.

Echinacea purpurea contains essential oils, vitamins A, C, E, echinocin, echinolone, calcium, selenium, silicon, magnesium, unique natural antioxidants and has anti-allergic, antimicrobial and immunostimulating effects. Its effect is synergistically enhanced in the presence of calendula, organically supplementing the complex chemical composition of Echinacea with purple provitamin A, which is of great importance for skin regeneration. So, in the Middle Ages, calendula was used to treat scab and unclean skin. Echinacea purpurea and calendula are presented as part of the product in the form of oil extracts.

The combination of vitamin E and vitamin A provides an antioxidant effect, protecting against the effects of free radicals on fatty acids, especially unsaturated, which are important for cell membranes, while reducing unsaturated bonds through the use of milk lipids, completely purified from protein and water, as the base fat ingredient allows you to direct their effect on the performance of protective functions.

The use of milk lipids in combination with beeswax provides an increase in penetrating ability and promotes the synthesis of skin's own ceramides, which inhibit transepidermal moisture loss and restore skin barrier functions.

The use of ingredients in the form of oil extracts in the product ensures the homogeneity of the mixture and the stable structure of the product, which does not separate and oxidize during storage.

The composition of the claimed cosmetic products for the healing and regeneration of the skin is prepared as follows. The solid mass of milk lipids, completely purified from protein and water, is loaded into the digester and with constant stirring is heated to a temperature of 75-80 ° C. At this temperature, compositional ingredients such as purified turpentine oil, propolis and purified beeswax are alternately added to the molten mass of milk lipids and kept under constant stirring and at a constant temperature for 30 minutes until a homogeneous homogeneous mass is obtained. The resulting mass is pumped under vacuum into a cooling boiler. When pumping, the mass is passed through a filter, cleaning from natural natural mechanical impurities. The purified mass, with constant stirring, is partially cooled and sea buckthorn oil, vitamin E, vitamin A, echinacea purpurea oil extract and calendula oil extract are introduced into it with stirring. The resulting mass is re-partially cooled with stirring, and lavender essential oil, tea tree essential oil and rosemary essential oil are added. The mass is homogenized to a homogeneous plastic state, cooled, aged and packaged in tubes.

A ready-made skin care product with a healing and regenerating effect is a product of soft consistency, light yellow in color, at room temperature has a pronounced viscosity and a specific smell. In contact with the surface of the human body or when heated to a temperature higher than 27 ° C, the product becomes fluid and plastic.

The practical applicability of the claimed invention is illustrated by the following examples of specific applications. Testing of cosmetic products was carried out on a group of 50 women for 12 months.

Example 1 (prototype)

The composition of Shigalov's balm “IDAS” was prepared with the ratio of ingredients, wt.%:

Sea buckthorn oil 0.57 Cedar Oil 0.52 Rosehip oil 0.66 Oil extracts of plant materials: Hypericum perforatum 0.83 Peony root 0.69 Calamus root 0.73 Chamomile flowers 1,56 Calendula flower 1.14 Thyme Herbs 10.52 Propolis extract 0,031 "Egg butter" 0.02 Beeswax 0.98 Sunflower oil Rest

which corresponds to the average content of ingredients within the claimed limits.

Indicators of funds received:

small wound healing time and foci of inflammation, frequency of use 2 times per day, h 50-73 texture topography improvement skin, frequency of use 2 times a day, h 42-60 penetration in biological tissue (test five hours after application), mg / cm ² 34 transepidermal moisture loss, g / h × m ² 23 dropping point, degrees 5 viscosity at 40 ° C, cSt 3 storage period, months eighteen color dark yellow smell sharp, specific, vegetable

The drug is a liquid.

Example 2

Prepare a composition of the claimed cosmetic product for skin regeneration. To do this, the solid mass of milk lipids, completely purified from protein and water, is loaded into the digester and with constant stirring is heated to a temperature of 75-80 ° C. At this temperature, composite ingredients such as purified turpentine oil, propolis extract and purified beeswax are alternately added to the molten lipid mass at this temperature, and they are kept under constant stirring and temperature for 30 minutes until a homogeneous homogeneous mass is obtained. The resulting mass is pumped under vacuum into a cooling boiler. When pumping, the mass is passed through a filter, cleaning from natural natural mechanical impurities. The purified mass with constant stirring is partially cooled and sea buckthorn oil, vitamin E, vitamin A, echinacea purpurea oil extract, marigold oil extract are partially cooled with stirring. The resulting mass is re-partially cooled with stirring, and lavender essential oil, tea tree essential oil and rosemary essential oil are added. The mass is homogenized to a homogeneous plastic state, cooled, aged and packaged in tubes.

Composite ingredients are added at the following content, wt.%:

Sea buckthorn oil 3.37 Lavender essential oil 0.45 Tea Tree Essential Oil 0.09 Rosemary essential oil 0.45 Turpentine oil 2.7 Echinacea purpurea oil extract 2.7 Marigold oil extract 2.7 Propolis extract 0.009 Vitamin E 0,054 Vitamin A 0.09 Beeswax 2,277 Milk lipids Rest

which corresponds to the minimum value of the ingredients in the inventive tool.

Indicators of funds received:

small wound healing time and foci of inflammation, frequency of use 2 times per day, h 45-70 texture topography improvement skin, frequency of use 2 times a day, h 38-60 penetration in biological tissue (test five hours after application), mg / cm ² 57 transepidermal moisture loss, g / h × m ² 5 dropping point (i.e. means turns into a liquid-like mass when contact with a surface of the person), ° C 36-37.5 storage period, months 36 viscosity at 40 ° C, cSt 10 color light yellow smell specific

Example 3

According to example 2. As a milk lipids used ghee.

Composite ingredients are added at the following content, wt.%:

Sea buckthorn oil 3.39 Lavender essential oil 0.5 Tea Tree Essential Oil 0.1 Rosemary essential oil 0.5 Turpentine oil 3.0 Echinacea purpurea oil extract 3.0 Marigold oil extract 3.0 Propolis extract 0.01 Vitamin E 0.059 Vitamin A 0.1 Beeswax 2,475 Milk lipids Rest

which corresponds to the average value of the ingredients in the claimed cosmetic.

Indicators of funds received:

small wound healing time and foci of inflammation, frequency of use 2 times per day, h 40-68 texture topography improvement skin, frequency of use 2 times a day, h 35-55 penetration in biological tissue (test five hours after application), mg / cm ² 57.5 transepidermal moisture loss, g / h × m ² 4,5 viscosity at 40 ° C, cSt eleven dropping point, degrees 36-37 storage period, months 36 color light yellow smell specific

Example 4

According to example 2.

Composite ingredients are added at the following content, wt.%:

Sea buckthorn oil 4.12 Lavender essential oil 0.55 Tea Tree Essential Oil 0.11 Rosemary essential oil 0.55 Turpentine oil 3.3 Echinacea purpurea oil extract 3.3 Marigold oil extract 3.3 Propolis extract 0.011 Vitamin E 0,066 Vitamin A 0.11 Beeswax 2,783 Milk lipids Rest

which corresponds to the maximum value of the ingredients in the claimed cosmetic.

Indicators of funds received:

small wound healing time and foci of inflammation, frequency of use 2 times per day, h 42-70 texture topography improvement skin, frequency of use 2 times a day, h 37-60 penetration in biological tissue (test five hours after application), mg / cm ² 53 transepidermal moisture loss 5 viscosity at 40 ° C, cSt 12 dropping point, degrees 37-39 storage period, months 36 color yellow smell sharply specific

Example 5

According to example 2.

Composite ingredients are added at the following content, wt.%:

Sea buckthorn oil 3.25 Lavender essential oil 0.4 Tea Tree Essential Oil 0.08 Rosemary essential oil 0.4 Turpentine oil 2,3 Echinacea purpurea oil extract 2,3 Marigold oil extract 2,3 Propolis extract 0.008 Vitamin E 0,048 Vitamin A 0.08 Beeswax 2.1 Milk lipids Rest

which corresponds to the value of the ingredients in the inventive tool below the declared limits.

Indicators of funds received:

small wound healing time and foci of inflammation, frequency of use 2 times per day, h 54-76 texture topography improvement skin, frequency of use 2 times a day, h 49-72 penetration in biological tissue (test five hours after application), mg / cm ² 37 transepidermal moisture loss 17 dropping point, degrees 28-30 storage period, months 24 viscosity at 40 ° C, cSt 9 color light yellow smell weakly specific

Example 6

According to example 2.

Composite ingredients are added at the following content, wt.%:

Sea buckthorn oil 4.15 Lavender essential oil 0.56 Tea Tree Essential Oil 0.12 Rosemary essential oil 0.6 Turpentine oil 3.35 Echinacea purpurea oil extract 3.35 Marigold oil extract 3.35 Propolis extract 0.012 Vitamin E 0.7 Vitamin A 0.12 Beeswax 2,8 Milk lipids Rest

which corresponds to the value of the ingredients in the inventive tool above the stated limits.

Indicators of funds received:

small wound healing time and foci of inflammation, frequency of use 2 times per day, h 50-72 texture topography improvement skin, frequency of use 2 times a day, h 41-65 penetration in biological tissue (test five hours after application), mg / cm ² 49 transepidermal moisture loss, g / h × m ² 5.5 dropping point, degrees 40-43 storage period, months 36 viscosity at 40 ° C, cSt fifteen color yellow smell sharply specific

As can be seen from the above examples 2-4, the inventive tool is workable and can reduce, compared with the prototype (example 1), the healing time of small wounds and foci of inflammation, with a frequency of application 2 times a day to 48-68 hours, to improve the topography of the skin texture with the frequency of use 2 times a day up to 35-55 hours, increase the penetrating ability in biological tissues (test five hours after application) to 57.5 mg / cm ² , reduce transepidermal moisture loss to 4.5 g / h × m ² and increase shelf life up to 36 months (example 3).

All ingredients of the product are taken in the optimal range to achieve the expected technical results.

A decrease in the amount of each ingredient of the product below the specified limit leads to a deterioration in the quality of the cosmetic product and a decrease in its prophylactic and therapeutic properties (Example 5).

Increasing the amount of each component above the specified limit is not economically feasible and violates the synergistic balance, which leads to excessive unilateral action of the individual components. The drug turns into a dense mass and does not perform its functions, for example, in case of burns, when it is necessary to evenly distribute the drug over the entire surface of the damage, without touching it (example 6).

Thus, the created cosmetic product for skin care with a healing and regenerating effect allows you to expand the arsenal of cosmetics with a new effective product that meets modern requirements, the effect of which determines a high level of oxidation-reduction processes, manifested in skin regeneration and normalization of intracellular metabolism. The cosmetic product is highly effective due to the high content of milk lipids, completely purified from protein and water, is universal and can be used for any skin area.

Claims (1)

Cosmetic for skin care with a healing and regenerating effect, containing beeswax, sea buckthorn oil, marigold oil extract, propolis extract, characterized in that it additionally contains lavender essential oil, tea tree essential oil, rosemary essential oil, turpentine oil, oil extract Echinacea purpurea, vitamin E, vitamin A and milk lipids in the following ingredients, wt.%:
sea buckthorn oil 3.37-4.12 lavender essential oil 0.45-0.55 tea tree essential oil 0.09-0.11 rosemary essential oil 0.45-0.55 turpentine oil 2.7-3.3 Echinacea purpurea oil extract 2.7-3.3 marigold oil extract 2.7-3.3 propolis extract 0.009-0.011 vitamin e 0,054-0,066 vitamin A 0.09-0.11 beeswax 2,277-2,783 milk lipids rest