RU2400207C1 - Method for blood microvesicle level correction in children with scoliosis - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to haematology and orthopaedics. Correction of blood microvesicle level in children aged 8-12 with scoliosis is ensured by the prescription of a therapeutic complex that involves daily therapeutic physical training, two courses of massage and daily swimming for at least 20 minutes a day, for at least 6 months.

EFFECT: method enables correcting blood microvesicle level in children aged 8-12 with scoliosis, optimising microcirculation in tissues, normalising functions of the internal organs, growth and development of a child.

7 ex

Description

The invention relates to medicine, namely to hematology and orthopedics.

Analogues of the proposed method for correcting the level of microvesicles in the blood of children 8-12 years old with scoliosis does not exist.

It is known that an important feature of the cytoplasmic membrane is the asymmetry of the phospholipid and protein composition of two sheets of the bilayer, which occurs under the action of intracellular enzymes, differences in the ionic composition of the cytoplasm and extracellular fluid. The asymmetry of the bilayer determines the atrombogenicity and hemocoagulation properties of blood cells and the endothelium of blood vessels and, in addition, is involved in creating a gradient of curvature, folds, wrinkling, and in laminating portions of the membrane in the form of microvesicles.

Fragments of cell membranes formed during exocytosis, necrosis and apoptosis are able to close and form vesicles with a diameter of 0.05 to 3.0 microns. The size of the microvesicles depends on the nature of the agent acting on the target cell. Microvesicles are of platelet and non-platelet origin. They form on the cell surface, desquamating with the cytoplasmic membrane. Therefore, they contain various membrane glycoproteins, cytoskeletal proteins, microfilaments, myosin chains, etc.

Microvesicles not only represent the catalytic surface for internal “tenase” (a supramolecular complex consisting of factor IXa, factor VIIIa and phospholipids) and the prothrombinase complex, but they are also able to influence the proteolytic inactivation of factors Va and VIIIa by activated protein C in conjunction with protein S. Therefore a decrease in the level of microvesicles in the blood leads to a decrease in the blood coagulation potential of platelet-free blood plasma.

With scoliosis in children, there is an increase in blood levels of microvesicles, causing an increase in coagulation capabilities of plasma. However, approaches to lowering the level of microvesicles in the blood remain very poorly developed. In scoliosis in children, such approaches have not previously been used. In children with scoliosis, physical therapy (physical therapy), massage and swimming are used to correct posture.

However, never before has a treatment complex consisting of exercise therapy, massage and swimming courses been used in children with scoliosis to lower their microvesicle level.

The aim of the invention is to lower the level of microvesicles in the blood of children with scoliosis.

The essence of the proposed method lies in the fact that to correct the level of microvesicles in the blood of children with scoliosis for at least 6 months. daily exercises are prescribed, two courses of massage and daily swimming for at least 20 minutes a day.

The method allows you to adjust the level of microvesicles in the blood of children with scoliosis for at least 6 months., Transferring it to a level close to that for healthy children. Subject to the subsequent recommendations of the proposed method, it is possible to maintain the level of microvesicles at an optimal level, which will significantly optimize microcirculation in the tissues of the child, optimizing growth and development, facilitating the functioning of internal organs, allowing the child to fully realize the incorporated genetic program of physical development in the child.

The inventive method is as follows.

The determination of the level of microvisicles in the blood is carried out by the activity of 5-nucleotidase in blood serum (L.D. Zubairova, D.M. Zubairov, I.A. Andrushko and others. Cellular microvesicles in the dynamics of experimental endotoxinemia. // Bulletin of experimental biology and medicine: monthly international scientific and theoretical journal / PAMH. - 2006. - Vol. 142, No. 11. - S.517-520). Normally, its level is 63.8 ± 2.5 nkat. With an increase in the level of microvesicles in the blood, children with scoliosis need to prescribe a treatment complex from daily exercise therapy, two courses of massage and daily swimming.

The first component of the method is recommended physical exercises below.

The complex consists of several parts: warm-up (exercise 1), exercises lying on your back, lying on your stomach and standing. Rest between exercises is performed in the initial position (i.e. if the exercise is lying on your back, we also rest in this position, you do not need to get up or sit down).

1. Unloading the spine. All exercise therapy exercises traditionally begin with exercises to unload the spine. The classic exercise is walking on all fours. Duration 2-3 minutes. We lay down on the litter on his back. Exercises on the back are designed primarily to strengthen the abdominal muscles.

2. "Traction" of the spine. Lying on your back, with your heels stretch "down", with your crown - "up". We perform 3-4 "traction" for 10-15 seconds.

3. The bike. Lying on your back, arms behind your head or along the torso, make movements with your feet that mimic a bike ride. Important: most of the amplitude of leg movements should be “lower” than the body, you don’t need to dabble over your stomach, it is necessary that the straightened leg alternately passes close to the floor. The pace is medium. We perform 2-3 sets of 30-40 seconds.

4. Scissors. Lying on your back, arms behind your head or along the torso, perform the neighboring horizontal and vertical swings with your feet. Important: gorintolnye swing is desirable to produce closer to the floor. The pace is medium. We perform 2-3 sets of 30-40 seconds. Now we turn over to the stomach. Exercises on the abdomen are designed primarily to strengthen various back muscles.

5. Traction. It is carried out similarly to exercise 2, only on a stomach.

6. Swimming. The starting position is lying on the stomach, legs are straight, the head rests on the back of the palms. We bend in the lower back (head, upper body, arms and legs are raised, fulcrum is the stomach). Holding this position, we perform movements simulating swimming breaststroke:

arms forward, legs apart

arms to the sides, legs to connect

arms to shoulders, legs still together.

We perform 2-3 sets of 10-15 repetitions with a short rest between sets (5-10 seconds).

7. Scissors. Lying on his stomach, legs are straight, his head rests on the back of his hands. Raise your legs and perform the surrounding horizontal and vertical swing legs. Important: when performing this exercise, the hips must be taken off the floor. The pace is medium. We carry out 2-3 approaches for 30-40 seconds.

8. Retention. Lying on his stomach, legs are straight, his head rests on the back of his hands. Raise the legs and upper body, caving in the lower back (head, upper body, arms and legs raised, fulcrum - stomach). Legs together, arms to the sides, palms turned up. Statically freeze in this position for 10-15 seconds. Important: it is advisable not to hold your breath, while performing this exercise, the hips must be torn off the floor. Perform 3-4 repetitions with a short rest between repetitions (5-10 seconds).

Then the baby gets up.

9. Rotation by hand. Exercise for scapula fixators. Standing in front of the mirror (controlling posture), elbows to the side, fingers to shoulders. Perform the rotation of the hands back (clockwise). Important: this exercise does not need a large range of motion, on the contrary, the elbows should make a small circle when rotating. The pace of execution is slow. We perform 2-3 sets of 20-30 seconds with a short rest between sets.

10. Squats. Posture exercise. Standing in front of the mirror (controlling posture), arms to the side, palms turned up. In this position, while maintaining a beautiful posture, we stand on the toes, then squat, again on the toes and in the starting position. We carry out 5-10 such squats with short rest. The pace of the exercise is slow.

The second component of the claimed method is to conduct two courses of massage.

A massage session begins from the back, from the side of the curvature, then the neck, lower back, and pectoral muscles are massaged.

The following techniques are applied: stroking of all kinds, rubbing, squeezing, kneading and vibration. Massage techniques for scoliosis are used depending on muscle tone. The duration and rhythm of their implementation should be the same in each massaged area until the muscles are completely relaxed. Massage techniques alternate with stroking and shaking. Subsequent massage sessions help strengthen muscles and increase their tone.

The back is massaged in the supine position, under the abdomen and under the ankle joints, rollers or small pillows are laid, hands are lowered along the body, the head is turned in the direction opposite to scoliosis. Optimal for massage of the chest and abdomen is the supine position, and it is better to put soft ridges under the head and knees. Hands the patient stretches along the body. Massage of the lateral surfaces of the body is carried out in the position of the child lying on his side, opposite to the curvature of the spine. The duration of the massage procedure is 30-40 minutes daily, the course of treatment consists of 20-25 sessions, during six months massage courses are carried out twice - at the beginning of treatment and 3 months after the end of the first course.

During a massage session, the patient’s position is lying on his stomach (the masseur is standing on the right), lying on his back (the masseur is on the patient’s left) or lying on the opposite side of chest scoliosis (the masseur is behind him — behind).

A child with scoliosis lies on his stomach, a massage therapist stands on the side of chest scoliosis. First, general strokes of the entire surface of the back are performed (planar, grasping, rake-shaped, ironing), then a sedative, relaxing effect on the upper part of the trapezius muscle is performed (stroking, rubbing with fingers - circular, continuous labile vibration), rubbing, kneading, vibration at elevation in elevation areas of thoracic scoliosis (comb-like rubbing, striking, chopping, kneading forceps along the long muscles of the back); all techniques for toning, stimulation to be carried out locally. After this, the area of lumbar concavity is massaged (all techniques for relaxing, stretching, acting sedatively - stroking, rubbing, vibration only labile, continuous).

The child turns on his left side. In this position, methods of pulling the right iliac crest are used. After that, the child lies on his stomach. Continue massage of the scoliosis area in the lumbar region, in the area of convexity (all methods of stimulation, toning - kneading, intermittent vibration, all varieties to strengthen the muscular cushion). Then, the subscapular region (left shoulder blade) is relaxed and stretched, paying attention to the intercostal space (rake stroking, rubbing, labile vibration), pulling the left corner of the shoulder blade from the concavity of the spine, stimulating and toning the shoulder girdle, muscles above the left shoulder blade, upper trapezius muscle (grinding kneading, intermittent vibration, as well as shock techniques).

The child rolls onto his back. In this position, massage the front surface of the chest.

In the subclavian and supraclavicular areas, as well as in the area of the pectoral muscles on the left, all techniques are used to stimulate, strengthen the muscular corset (rubbing, kneading, intermittent vibration, shock techniques). In the area of the anterior rib hump (bulging), receptions are performed with pressure on this area with backward movements, alignments; massage manipulations with the aim of stimulation, toning. On the front abdominal wall, abdominal press, all methods of stimulation, toning are performed (rubbing comb-like, kneading, intermittent vibration, shock). On the upper part of the pectoral muscles on the right, they do all the techniques for relaxing and pulling the shoulder back, leveling the plane of the shoulders. The massage is completed by general stroking of the entire back, shoulders.

The third component of the claimed method is the daily swimming of the child in the sea, river or pool for at least 20 minutes a day.

Example 1. In child A., 8 years old, with scoliosis of the II degree, examination revealed an increase in the level of microvesicles in blood plasma of 146.6 nkat. The child was assigned to at least 12 months of daily exercise therapy. The child was regularly examined after the start of treatment. Simultaneously with the examination, the level of microvesicles in the blood was determined.

After 12 months treatment, the child retained signs of scoliosis with an increased level of microvesicles in the blood, amounting to 123.6 nkat.

Parents of the child were invited to comply with the recommendations given to their child, subsequently in combination with massage and swimming.

Example 2. In a child K., 10 years old, with scoliosis of the first degree, an examination revealed an increase in the level of plasma microvesicles of 143.8 nkat. The child was assigned for at least 12 months. 4 massage courses. The child was regularly examined after the start of treatment. Simultaneously with the examination, the level of microvesicles in the blood was determined.

After 12 months treatment, the child retained signs of scoliosis with an increased level of microvesicles in the blood, amounting to 124.3 nkat.

Parents of the child were invited to comply with the recommendations given to their child, subsequently in combination with exercise therapy and swimming.

Example 3. In a child S., 11 years old, with scoliosis of the II degree, examination revealed an increase in the level of microvesicles in blood plasma of 147.3 nkat. The child was assigned for at least 12 months. daily swimming for at least 20 minutes a day. The child was regularly examined after the start of treatment. Simultaneously with the examination, the level of microvesicles in the blood was determined.

After 12 months treatment of a child, the signs of scoliosis decreased with a decrease in the level of microvesicles in the blood, amounting to 128.6 nkat.

Parents of the child were invited to comply with the recommendations given to their child, subsequently in combination with exercise therapy and massage.

Example 4. In a child M., 12 years old, with scoliosis of the II degree, examination revealed an increase in the level of plasma microvesicles of 145.5 nkat. The child was assigned for at least 12 months. daily exercise classes and 4 courses of massage during the year of classes. The child was regularly examined after the start of treatment. Simultaneously with the examination, the level of microvesicles in the blood was determined.

After 12 months treatment of a child, the signs of scoliosis decreased with a decrease in the level of microvesicles in the blood, which amounted to 95.7 nkat.

Parents of the child were invited to comply with the recommendations given to their child, subsequently in combination with swimming.

Example 5. In a child P., 8 years old, with scoliosis of the first degree, an examination revealed an increase in the level of plasma microvesicles of 143.9 nkat. The child was assigned for at least 12 months. daily exercise therapy and daily swimming for at least 20 minutes a day. The child was regularly examined after the start of treatment. Simultaneously with the examination, the level of microvesicles in the blood was determined.

After 12 months treatment, the child disappeared signs of scoliosis with a decrease in the level of microvesicles in the blood, amounting to 94.9 nkat.

Parents of the child were invited to comply with the recommendations given to their child, subsequently in combination with massage.

Example 6. In a child R., 12 years old, with scoliosis of the II degree, examination revealed an increase in the level of plasma microvesicles of 147.7 nkat. The child was assigned for at least 12 months. 4 massage courses and daily swimming for at least 20 minutes a day. The child was regularly examined after the start of treatment. Simultaneously with the examination, the level of microvesicles in the blood was determined.

After 12 months treatment, the child retained signs of scoliosis with an increased level of microvesicles in the blood, comprising 95.5 nkat.

Parents of the child were invited to comply with the recommendations given to their child, subsequently in combination with exercise therapy.

Example 7. In a child K., 9 years old, with scoliosis of the II degree, examination revealed an increase in the level of plasma microvesicles of 149.0 nkat. The child was assigned for 12 months. daily exercise therapy, two courses of massage - the first course at the beginning of treatment, the second - 3 months after the end of the first course and daily swimming for at least 20 minutes a day. The child was regularly examined after the start of treatment. Simultaneously with the examination, the level of microvesicles in the blood was determined.

Already after 6 months. treatment, the child disappeared signs of scoliosis with normalization of the level of microvesicles in the blood, amounting to 60.4 nkat.

Parents of the child were asked to follow the recommendations given to their child in the future.

Using the proposed method for correcting the level of microvesicles in the blood in hematology and orthopedics will help not only to level the signs of scoliosis in children, but also to optimize the growth and development of children with scoliosis, optimizing their microcirculation in tissues, allowing maximum use of the reserve forces of the body.

Claims (1)

A method for correcting the level of microvesicles in the blood of children aged 8-12 with scoliosis by applying daily physical therapy, two courses of massage and daily swimming for at least 20 minutes a day for 6 months.