RU2365292C1 - Dietary supplement - Google Patents

Abstract

FIELD: food products. ^ SUBSTANCE: dietary supplement (DS) "Lactussil" is based on honey extract of holy thistle seeds. Holy thistle seeds are grown in milk whey medium during 3 days and extracted by honey in ratio grown seeds : honey = 1:2 during 42 days in dark place. After that obtained honey extract is mixed with lactulose and malic acid (taken for 100 kilos of dietary supplement): lactulose - 50 kilos, honey extract of grown holy thistle seeds - 49,75 kg, malic acid - 0,25 kg. ^ EFFECT: high biological value, strong bifidus-factor, general tonic, restorative and immunostimulatory effect. ^ 3 tbl

Description

The invention relates to the food industry, in particular to biologically active additives (hereinafter Supplements).

The widespread use of dietary supplements is an affordable and effective way to optimize nutrition. As raw materials for the production of dietary supplements, certain types of products of plant, animal, mineral origin, their components or synthetic analogues are used.

Spotted milk thistle is widely used as a biologically active additive due to the rich composition of biologically active substances and the presence of a rarely found in nature biologically active substance - silymarin.

Known biologically active additives based on the seeds of milk thistle: "Milk thistle with echinacea", "Milk thistle with hibiscus and wild rose", "Milk thistle with burdock" [1].

Milk thistle seedlings - small plants 1-1.5 cm long at the age of 6 days have the most active and multilateral pharmacological action. They contain a complete set of active flavonoids embedded in the living tissue of the plant. Milk thistle sprouts are a highly effective hepatoprotector. They have a pronounced choleretic effect, activate the secretory and motor functions of the gastrointestinal tract [2].

The basis of these dietary supplements is only vegetable raw materials, which limits the possibility of additives, since there is no factor affecting human energy.

The technical solution is to increase the biological activity of the additive, expanding the range and capabilities of the additive.

This is achieved by the fact that the proposed biologically active additive "Lactusil" based on milk thistle seeds, germinated in whey (which reduces the germination time by half), which is extracted with honey in the ratio of germinated seeds: honey = 1: 2 for 42 days in a dark place , and then the extract is mixed with lactulose and malic acid per 100 kg of dietary supplement, kg:

Lactulose fifty Milk Thistle Seed Extract 49.75 Apple acid 0.25

The technological process for the production of dietary supplements "Lactusil" includes the germination of milk thistle seeds in milk whey, the preparation of a honey extract of germinated milk thistle seeds, mixing the extract with lactulose and malic acid.

Milk thistle seeds are washed, placed in one layer between two layers of linen or cotton cloth, soaked in warm water, and left at (+22) - (+ 24) ° С. The upper tissue 2 times a day (morning and evening) moisturize with whey. After 3 days, the length of the seedlings should be 1.0-1.5 cm. The seeds are sorted, washed with distilled water, dried at a temperature of 60 ° C for 1.5 hours.

To prepare the extract, germinated seeds of milk thistle and honey of light varieties are used in a ratio of 1: 2. The extraction process is 42 days in a dark place. Then the extract is filtered in an oven when heated to 60 ° C, malic acid is added to the filtrate in an amount according to the recipe (table 1) and the resulting product is thoroughly mixed with lactulose to a homogeneous mass. You can use any concentrate of food lactulose with a lactulose content of at least 30%.

Table 1 Recipe for dietary supplement "Lactusil" per 100 kg of product name of raw materials Amount kg Lactulose Concentrate "Lactusan" fifty Milk Thistle Seed Extract 49.75 Apple acid 0.25

From a chemical point of view, honey is a complex mixture of substances, which determines the diversity of its biological properties. Honey is a valuable natural source of easily digestible carbohydrates, vitamins (mainly water-soluble), enzymes, many macro- and microelements, which are associated with the potential promise of using honey in dietary supplements. Honey is recommended in the prevention of cardiovascular diseases, as it reduces blood viscosity, improves lipid metabolism, stabilizes blood pressure, increases performance, supports the body’s immunity, muscle tone, as it is quickly absorbed by muscle cells due to the presence of glycutyl in its composition, and quickly restores energy losses.

In the proposed dietary supplement, honey is an extractant and is enriched with biologically active components of plant materials - sprouted seeds of milk thistle.

Milk Thistle (lat. Silybum Marianum) as a medicinal plant has been known for more than two thousand years. Milk thistle seeds contain easily digestible fiber, vitamins (groups B, A, D, F, E, K), micro- (manganese, copper, zinc, chromium, selenium, iodine, boron) and macronutrients (potassium, calcium, magnesium, iron ), fatty (up to 32%) and essential (0.08%) oils, biogenic amines (tyramine, histamine), natural resins, factor T (increasing the number of platelets in the blood), a unique set of omega-3 polyunsaturated fatty acids in optimal ratio. The lipid complex is represented by tocopherols, phospholipids, acylglycerols [3]. In addition, it has a feature that distinguishes it from other plants. This is a biologically active substance that is rarely found in nature - silymarin - a complex of flavonoids and flavolignans (quercetin, silibinin, silidianin, silicristin, taxifolin). Due to the phenolic structure of its active substances, silymarin is able to bind free radicals and inhibit lipid peroxidation processes, protecting liver cell membranes from destruction. Along with the antioxidant effect, the active substances of silymarin increase the content of glutathione in the liver, maintaining a normal level of detoxification [4]. In addition, milk thistle has a beneficial effect on digestion, enhancing the functions of bile formation and bile secretion. A very important property of milk thistle is that it has no contraindications and side effects.

Lactulose is a disaccharide consisting of fructose and galatose molecules connected by a glycosidic bond. On the basis of lactulose, more than 40 medications have been created [5]. Lactulose has high bifidogenic activity, the ability to restore the protective microflora of the intestine, to prevent diseases of the liver and gastrointestinal tract, is a classic bifidus factor.

Malic acid in the food industry is used as a preservative (E296). The use of pure synthetic malic acid is allowed in an amount of not more than 12% [6]. Malic acid is a white crystalline powder, without heating, it is sparingly soluble in the honey extract of germinated milk thistle seeds.

In the developed Lactusil dietary supplement based on milk thistle seeds grown in milk serum, the honey extract of the seeds is combined with lactulose concentrate, which made it possible to obtain a dietary supplement containing honey carbohydrates, biologically active components of the germinated milk thistle seeds, malic acid, and lactulose, a product of milk processing, which is lactulose, which is prebiotic of high bifidogenic activity. The composition of the dietary supplement determined its functional properties in case of cholecystitis, inflammation of the bile ducts and gallstone disease, disease of the spleen, thyroid gland, blood, as well as in the deposition of salts, expansion of the veins, edema, dropsy, obesity, radiculitis, joint pain, hemorrhoids, allergic diseases, and also with exhaustion of the body, colds and infectious diseases, metabolic disorders, cardiovascular pathology, to replenish energy costs, maintain and restore intestinal microflora, metabolic homeostasis.

The composition of dietary supplements was developed taking into account the daily needs of the body in biologically active substances contained in the patented supplement [7]. When using 1 dessert spoon (8 g) of dietary supplement 1 time per day, the daily need of the body for lactulose is satisfied by 90%; polyphenols - by 1.8%; flavonoids - by 1.1%; Vitamin E - by 1.3%; malic acid - by 4%.

The composition of the dietary supplement composition must meet not only the achievement of its intended functional properties, but also such indicators as product compatibility by properties (humidity, acidity, fat content, density, etc.), organoleptic, and the period of guaranteed shelf life of the product. The composition of the proposed dietary supplement meets these requirements.

The honey extract of the germinated seeds of milk thistle in a ratio of 1: 2 is a homogeneous viscous liquid that mixes well with lactulose concentrate - syrup, which is also a slightly viscous liquid. Malic acid gives the composition a pleasant sour taste and prevents the precipitation of lactose.

Thanks to the developed technology for producing dietary supplements, the biologically active substances of the components are preserved in their native state (even such mobile ones as vitamins and enzymes).

Table 2 presents data on the nutritional value of dietary supplements based on a honey extract of milk thistle seeds grown in milk whey with the addition of malic acid and lactulose ^* . ( ^* The recipe used a lactulose concentrate of the food composition shown in table 3.)

table 2 Nutrition value of 100 g dietary supplement "Lactusil" Carbohydrates 33.0 g Fats 9.6 g Organic acids 0.35 g Squirrels 10.31 g The energy value 260.69 kcal

Table 3 Composition of food lactulose syrup The name of indicators Nutritional structure Mass fraction,%: dry matter 58.6 Lactulose 34.6 Lactose free 12,2 Galactose 7.1 other sugars 1.3 total nitrogen 0.05 Ash 0.63 Calcium 0.21 Sodium 0.4 Magnesium 0,03 Phosphorus 0,03 Potassium 0.04

The developed biologically active food supplement based on the honey extract of milk thistle seeds grown in milk whey with the addition of malic acid and lactulose is an antioxidant, immunostimulating, anti-inflammatory, bactericidal, mildly tonic and general strengthening agent that stimulates the development of bifidoflora, a source of cost for replenishing the body.

Recommended dosage: adults - 1 dessert spoon (8 g) 2 times a day with meals. For children, the dose is reduced by 2 times. Duration of admission is 6 weeks.

Information sources

1.http: //www.zdravushka.ru/prod.htm.

2.http: //medinfa.ru/article/92/117328/.

3.http: //www.volgograd.ru/theme/info/zozh/lekari/38415.pub.

4. Tokaev E.S., Nekrasov E.A. Physiologically functional ingredients of hepatotropic action // Food Ingredients. Raw materials and additives. 2007, No. 2, p. 58.

5. Sugar substitutes // Food ingredients. Raw materials and additives. 2001, No. 2, p. 42.

6. Golubev V.N., Chicheva-Filatova L.V., Shlenskaya T.V. Nutritional and dietary supplements. - M .: ACADEMIA, 2003.

7. Recommended levels of food intake of food and biologically active substances MP 2.3.1.1915-04 // M., 2004, - 34 S.

Claims (1)

Biologically active food supplement based on germinated milk thistle seeds, characterized in that milk thistle seeds are germinated in whey for 3 days, extracted with honey in the ratio of germinated milk thistle: honey = 1: 2 for 42 days in a dark place, then mixed with lactulose and malic acid per 100 kg of dietary supplement:
Lactulose 50 kg Milk Thistle Seed Extract 49.75 kg Apple acid 0.25 kg