RU2344811C2 - Drug enhancing productivity of brood sows - Google Patents

Abstract

FIELD: medicine; veterinary.

SUBSTANCE: drug includes Premix P 54-3, oilcake, benthos, table salt, DAFS - 25, malt sprouts.

EFFECT: enhanced productivity of brood sows.

8 tbl, 2 ex

Description

The invention relates to veterinary medicine, relates to a compositional means for increasing the productivity of pregnant sows.

The organization of rational feeding of pregnant sows should be based on the knowledge of their need for energy, protein and other nutrient and biologically active substances necessary to ensure the planned productivity and maintenance of normal functioning of the body and the function of reproduction / 1 /.

Economic damage occurs due to death, growth retardation and loss of animal productivity, weakening of resistance and increasing susceptibility to other diseases, as well as therapeutic and preventive measures aimed at compensating for the above processes.

The main source of minerals and vitamins for farm animals is feed and partially water. Moreover, their content in feed is subject to significant fluctuations and varies depending on the type of plant, variety, vegetation, place of growth, soil, growing conditions. An important role in increasing the production of pig production, along with a decrease in the incidence and mortality rate, is played by an increase in the number of pigs, i.e. increase in piglet yield per sow.

Among non-communicable diseases, a significant proportion is the violation of mineral metabolism, vitamin and protein deficiency. In practice, various means are used to correct metabolic disorders, however, they do not always meet the requirements of the consumer because of their high cost and lack of effectiveness / 2 /.

Currently, effective feed and therapeutic additives are used. These include bentonites, phosphorites, chalk, sapropels, etc. / 3 /. However, all these funds are one-component and have a limited effect on metabolic processes in the animal's body.

Protein-vitamin supplements (BVD), also currently used, have an incomplete mineral composition, which forces the introduction of additional feeds / 4 /.

The above circumstances lead to the need for the development and implementation in livestock farming of pharmacological agents with a complex effect, high efficiency and, most importantly, safe for the health of animals, humans and the environment.

Promising in this regard may be the development of multicomponent drugs containing in their composition substances that affect the entire metabolism as a whole.

To solve the above issues, it is advisable to use the claimed tool, the mechanism of action of which is due to filling the deficit of vital minerals, as well as vitamins and proteins, improving digestibility and digestibility of feed, normalizing metabolic processes in the body of pigs by ensuring a healthy diet.

Known means for balancing nutrition and correcting the mineral metabolism of pregnant sows - premix P 54 - 3, which contains vitamins: A, D ₃ , E, B ₂ , B ₃ , B ₄ , B ₅ , C; micro and macro elements: Fe, Mn, Cu, Zn, Co, I; methionine, an antioxidant, a filler, allowing, thus, balancing rations for vitamins and micro, macrocells, etc. /four/.

Table 1 The component composition of the premix P 54-3 Components Content in 1 t Units Vitamin A 1500 Million ME - // - D ₃ 200 - // - - // - E 1000 g - // - B ₂ 300 - // - - // - B ₃ 1000 - // - - // - B ₄ thirty - // - - // - At ₅ 2200 - // - -//- FROM twenty kg Fe 5000 g Mn 3000 - // - Cu 500 - // - Zn 6000 - // - With 60 - // - L thirty - // - Methionine fifty kg Wheat bran up to 1000 - // -

The disadvantages of the prototype are the lack of such vital macro- and micronutrients as calcium, phosphorus, sodium, sulfur, silicon, selenium, etc., which is extremely negative for the health and productivity of pigs. In addition, the feed is poor in vegetable fats, proteins and carbohydrates, as well as biologically active substances.

The purpose of the invention is the development of a multicomponent agent for the prevention of protein-mineral-vitamin deficiency and increase the productivity of pregnant sows.

This goal is achieved by using a means to increase the productivity of pregnant sows, containing premix P 54-3, sunflower meal, composite Bentos, table salt, DAFS-25 and malt sprouts in the following ratio of components, wt.%:

Premix P 54-3 - 10.0-12.0,

Sunflower meal - 40.0-45.0,

Bentos - 1.0,

Table salt - 0.5,

DAFS-25 - 0.000016,

Malt sprouts - the rest.

The tool is recommended to be introduced into the diet of pregnant sows at a dose of 0.3 g / kg live weight per day. The drug can be fed individually or with group feed.

The product is intended for use as a feed additive to feed and feed mixtures for pregnant sows in order to prevent protein-mineral-vitamin deficiency and increase their productivity.

Sunflower meal is obtained by pressing pre-processed sunflower seeds on screw presses. Sunflower meal is a source of valuable protein, fats, vitamins / 3, 6 /.

Premix P 54-3 contains vitamins: A, D ₃ , E, B ₂ , B ₃ , B ₄ , B ₅ , C; micro and macro elements: Fe, Mn, Cu, Zn, Co, I; methionine, an antioxidant, a filler, allowing, thus, balancing diets for vitamins and micro-, macrocells, etc., allowing, thus, partially balancing diets for vitamins and micro-, macronutrients, etc. /four/.

Bentos is a composite preparation for the correction of mineral metabolism disorders and contains in optimal proportions aluminosilicates consisting of montmorillonite - (OH) ₄ Sig (Al _3.34 , Mg _0.56 , Na _0.66 ) and amorphous silica. It consists of more than 40 different elements that are vital for animals: silicon, sodium, potassium, calcium, magnesium, phosphorus, iron, manganese, copper, zinc, cobalt, iodine, etc .; phosphorus in terms of P ₂ O ₅ - 52%, and in terms of phosphorus element - 22.7%, nitrogen soluble in 0.4% hydrochloric acid less than 10%; calcium sulfate dehydrate (CaSO ₄ 2H ₂ O - not less than 92%, alkali metal silicofluorides (Na, K) ₂ SiF ₆ , calcium fluoride CaF ₂ , iron and aluminum phosphates, fluoroappatites, nepheline, silicates) / 5 /.

table 2 The content of the main elements in the drug "Bentos" Indicators Content Phosphorus No less than 42 g / kg Calcium No less than 190 g / kg Sulfur No less than 90 g / kg Nitrogen No less than 11 g / kg Silicon No less than 171 g / kg Copper Not less than 13.1 mg / kg Manganese Not less than 40.0 mg / kg Zinc Not less than 35.0 mg / kg Cobalt No less than 4.0 mg / kg Iodine Not less than 0.15 mg / kg Vanadium No less than 16.5 mg / kg Chromium Not less than 70.0 mg / kg Zirconium Not less than 43.0 mg / kg Yttrium No less than 12.2 mg / kg Ytterbium No less than 3.0 mg / kg Barium No less than 1.2 mg / kg Strontium Not less than 29.0 mg / kg Helium At least 17.0 mg / kg Nickel No less than 24.0 mg / kg Molybdenum Not less than 0.8 mg / kg

Salt contains 30% sodium and 57% chlorine, is a vital compound / 6 /.

The drug DAFS-25 contains selenium, with a deficiency of which white muscle disease develops, toxic liver dystrophy. This chemical element is involved in the antioxidant defense of the body / 6 /.

Malt sprouts are obtained by germinating barley when receiving wort, the mass of light gray, bitter in taste, is hygroscopic. They are obtained at brewing enterprises by separating from germinated and dried barley upon receipt of malt / 3 /.

A means for increasing the productivity of pregnant sows is made as follows. Cake sunflower and malt sprouts are additionally crushed (grain size should not exceed 2.5 ± 0.5 mm) and mixed with premix P 54-3, sodium chloride and Bentos preparation, and selenium-containing preparation DAFS-25 is introduced last.

Then the product is dried at a temperature of 40-45 ° C with obligatory convection and stirring to a total humidity of not more than 10-12%.

The finished mixture should have a friable consistency.

EXAMPLE 1. Determination of the optimal ratio of the components of the funds to increase the productivity of pregnant sows.

We selected 2 groups of pregnant sows with 10-12 heads each, sows of the experimental group used means to increase the productivity of pregnant sows throughout the entire period of pregnancy. The control group to the main diet received premix P 54-3, the beginning of the experiment corresponded to the beginning of pregnancy (insemination day).

The results of a clinical trial of a drug with different ratios of components in comparison with P 54-3 are presented in tables 3, 4, 5, 6, 7.

Table 3 The effectiveness of the product to increase the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 8.0, sunflower meal - 60.0, benthos - 0.5, table salt - 0.5, DAFS - 25 - 0 , 000016, malt sprouts - the rest (option A) No. p / p Groups Terms of stabilization of biochemical parameters of blood * pregnant sows one The claimed tool (option A) 26 2 Premix P 54-3 24 * - data averaged by group Table 4 The effectiveness of the product to increase the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 12.0, sunflower meal - 15.0, bentos - 1.5, table salt - 0.5, DAFS-25 - 0 , 000016, malt sprouts - the rest (option B) No. p / p Groups Terms of stabilization of biochemical parameters blood * pregnant sows one The claimed tool (option B) 46 2 Premix P 54-3 24 * - data averaged by group

Table 5 The effectiveness of the means for correcting metabolic disorders and increasing the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 10.0, sunflower meal - 44.0, bentos - 1.0, table salt - 0.5, DAFS-25 - 0.000016, malt sprouts - the rest (option B) No. p / p Groups Terms of stabilization of biochemical parameters of blood * pregnant sows one The claimed tool (option B) 13 2 Premix P 54-3 24 * - data averaged by group

Table 6 The effectiveness of the means for correcting metabolic disorders and increasing the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 12.0, sunflower meal - 45.0, bentos - 1.0, table salt - 0.5, DAFS-25 - 0.000016, malt sprouts - the rest (option D) No. p / p Groups Terms of stabilization of biochemical parameters of blood * pregnant sows one The claimed tool (option D) twenty 2 Premix P 54-3 24 * - data averaged by group

Table 7 The effectiveness of the means for correcting disturbances in mineral metabolism and increasing the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 10.0, sunflower meal - 40.0, bentos - 1.0, table salt - 0.5, DAFS-25 - 0.000016, malt sprouts - the rest (option D) No. p / p Groups Terms of stabilization of biochemical parameters of blood * pregnant sows one The claimed tool (option D) 19 2 Premix P 54-3 24 * - data averaged by group

EXAMPLE 2. Determination of the effectiveness of the means for the correction of disorders of mineral metabolism and increase the productivity of pregnant sows.

Groups of pregnant sows with 10-12 heads each were selected.

The first group received Premix P 54-3. The second is a means to increase the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 8.0, sunflower meal - 60.0, benthos - 0.5, table salt - 0.5, DAFS-25 - 0.000016, malt sprouts - the rest (option A). The third is a means to increase the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 12.0, sunflower meal - 15.0, benthos - 1.5, table salt - 0.5, DAFS-25 - 0.000016, malt sprouts - the rest (option B). Fourth - a tool for correcting metabolic disorders and increasing the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 10.0, sunflower meal - 44.0, bentos - 1.0, table salt - 0.5 , DAFS-25 - 0.000016, malt sprouts - the rest (option B). Fifth - a tool for correcting metabolic disorders and increasing the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 12.0, sunflower meal - 45.0, bentos - 1.0, table salt - 0.5 , DAFS-25 - 0.000016, malt sprouts - the rest (option D). Sixth - a tool for correcting metabolic disorders and increasing the productivity of pregnant sows with a ratio of components, wt.%: Premix P 54-3 - 10.0, sunflower meal - 40.0, bentos - 1.0, table salt - 0.5 , DAFS-25 - 0.000016, malt sprouts - the rest (option D).

Table 8 Determination of the effectiveness of the means for correcting disorders of mineral metabolism and increasing the productivity of pregnant sows No. p / p Groups Received piglets from one sow (at weaning), goal. * Preservation,% * Milk content, kg * one Premix P 54-3 9.38 96.5 43.66 2 The claimed tool (option A) 9.35 89.6 41.25 3 The claimed tool (option B) 9.55 93.1 47.12 four The claimed tool (option B) 9.91 96.8 51.32 5 The claimed tool (option D) 8.8 93.1 50.21 6 The claimed tool (option D) 9.3 94.3 50.63 * - data averaged by group

As can be seen from the table, the best results in terms of stabilization of biochemical blood parameters, clinical condition and productivity were obtained in the group of animals that used the claimed agent with a ratio of components, wt.%:

Premix P 54-3 - 10.0,

Sunflower meal - 44.0,

Bentos - 1.0,

Salt - 0.5,

DAFS-25 - 0.000016,

Malt sprouts - the rest.

As a result of the analysis of scientific, technical and patent literature, no means of the declared qualitative and quantitative composition were revealed, which indicates compliance with the criterion of "novelty." A qualitative composition provides an improvement in metabolic processes in the animal’s body and an increase in productivity, and a quantitative composition ensures an optimal level of exposure, which indicates compliance with the criterion of “inventive step”.

The safety and environmental safety of the claimed product was studied in accordance with the requirements approved by the Veterinary Department of the Ministry of Agriculture of the Russian Federation and guidelines for determining the toxic properties of drugs used in veterinary medicine, according to GOST 12.1.007 - 76, hazard class 4 (medium lethal dose of LD ₅₀ from due to low toxicity it is not possible to determine). It does not have skin-resorptive, allergenic, embryotoxic, teratogenic, cumulative properties and a sensitizing effect / 7 /.

The claimed tool when used does not cause complications and has no contraindications; slaughter for meat is carried out without restrictions associated with its use.

Information sources

1. Norms and diets of feeding farm animals. Reference manual. 3rd ed., Revised and supplemented. / Ed. A.P. Kalashnikov, V.I. Fisinina, V.V. Shcheglova, V.N. Kleimenov. - M., 2003 .-- 456 p.

2. Samokhin V.T. Prevention of metabolic disorders in microelements in animals (2nd Edition supplemented). / V.T.Samokhin. - Voronezh: Voronezh State University, 2003. - 136 p.

3. Petrukhin I.V. Feed and feed additives. / I.V. Petrukhin. - M .: Rosagropromizdat, 1989 .-- 526 p.

4. Fodder, feed additives and milk replacer for animals (composition and use). Directory. / V.A. Krokhina, A.P. Kalashnikov, V.I. Fisinin, and others; Ed. V.A. Krokhina. - M .: Agropromizdat, 1990 .-- 304 p.

5. Taravkov A.A. The drug "Bentos" in the experiment and clinic for violations of the mineral metabolism of laying hens. Abstract. dis. candidate vet. sciences. / A.A. Taravkov. - Voronezh, VNIVIPFiT, 2006. - 22 p.

6. Chernyshev N.I. Components of premixes. / N.I. Chernyshev, I.G. Panin. - Voronezh: "Publishing and printing company" Voronezh ", 2003. - P.6-94.

7. Argunov M.N. Guidelines for the toxicological and environmental assessment of drugs used in veterinary medicine. - Voronezh, 1998 .-- 26 p.

Claims (1)

Means for increasing the productivity of pregnant sows based on premix P54 - 3, characterized in that it additionally contains sunflower cake, bentos, table salt, DAFS-25 and malt sprouts in the following ratio of components wt.%:
Premix P54-3 10.0-12.0 Sunflower meal 40.0-45-0 Benthos 1,0 Common salt 0.5 DAFS-25 0.000016 Malt sprouts rest