RU2321402C2 - Фармацевтические композиции, содержащие макролиды - Google Patents

Фармацевтические композиции, содержащие макролиды Download PDF

Info

Publication number
RU2321402C2
RU2321402C2 RU2004116067/15A RU2004116067A RU2321402C2 RU 2321402 C2 RU2321402 C2 RU 2321402C2 RU 2004116067/15 A RU2004116067/15 A RU 2004116067/15A RU 2004116067 A RU2004116067 A RU 2004116067A RU 2321402 C2 RU2321402 C2 RU 2321402C2
Authority
RU
Russia
Prior art keywords
compound
formula
amino
iia
compounds
Prior art date
Application number
RU2004116067/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2004116067A (ru
Inventor
Йозеф Готтфрид МАЙНГАССНЕР (AT)
Йозеф Готтфрид Майнгасснер
Original Assignee
Новартис Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0127341A external-priority patent/GB0127341D0/en
Application filed by Новартис Аг filed Critical Новартис Аг
Publication of RU2004116067A publication Critical patent/RU2004116067A/ru
Application granted granted Critical
Publication of RU2321402C2 publication Critical patent/RU2321402C2/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
RU2004116067/15A 2001-10-23 2002-10-22 Фармацевтические композиции, содержащие макролиды RU2321402C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0125443.2A GB0125443D0 (en) 2001-10-23 2001-10-23 Organic Compounds
GB0125443.2 2001-10-23
GB0127341.6 2001-11-14
GB0127341A GB0127341D0 (en) 2001-11-14 2001-11-14 Organic compounds

Publications (2)

Publication Number Publication Date
RU2004116067A RU2004116067A (ru) 2005-04-20
RU2321402C2 true RU2321402C2 (ru) 2008-04-10

Family

ID=26246689

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004116067/15A RU2321402C2 (ru) 2001-10-23 2002-10-22 Фармацевтические композиции, содержащие макролиды

Country Status (19)

Country Link
US (1) US7259170B2 (enExample)
EP (1) EP1439838A1 (enExample)
JP (1) JP2005509634A (enExample)
KR (2) KR20090114483A (enExample)
CN (1) CN1307993C (enExample)
AU (1) AU2002346859C1 (enExample)
BR (1) BR0213463A (enExample)
CA (1) CA2458690C (enExample)
EC (1) ECSP045086A (enExample)
GB (1) GB0125443D0 (enExample)
HU (1) HUP0402108A3 (enExample)
IL (1) IL160973A0 (enExample)
MX (1) MXPA04003738A (enExample)
NO (1) NO20042074L (enExample)
NZ (1) NZ532412A (enExample)
PL (1) PL368533A1 (enExample)
RU (1) RU2321402C2 (enExample)
WO (1) WO2003035068A1 (enExample)
ZA (1) ZA200401711B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005512946A (ja) * 2001-05-09 2005-05-12 ノバルティス アクチエンゲゼルシャフト 選択的免疫調節法
MXPA04006709A (es) 2002-01-11 2004-10-04 Sankyo Co Derivados de aminoalcohol o derivados de acido fosfonico y composiciones farmaceuticas que los contienen.
GB0307867D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Pharmaceutical composition
KR20110136901A (ko) 2004-02-24 2011-12-21 상꾜 가부시키가이샤 아미노 알코올 화합물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2108338C1 (ru) * 1991-09-09 1998-04-10 Мерк Энд Ко., Инк. Имидазолидильный макролид, или его изомеры, или его фармацевтически приемлемая соль, способы его получения и фармацевтическая композиция, обладающая иммунодепрессивной активностью

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68921934T2 (de) 1988-06-29 1995-10-19 Merck & Co Inc Immunsuppressives Agens.
ATE126803T1 (de) * 1989-11-09 1995-09-15 Sandoz Ag Heteroatome enthaltende tricyclische verbindungen.
US5352671A (en) * 1989-11-09 1994-10-04 Sandoz Ltd. Heteroatoms-containing tricyclic compounds
GB2252041A (en) * 1991-01-23 1992-07-29 Fujisawa Pharmaceutical Co Use of macrolide compounds in treatment of autoimmune myocarditis
AU664178B2 (en) * 1991-03-19 1995-11-09 Vithal J. Rajadhyaksha Compositions and method comprising aminoalcohol derivatives as membrane penetration enhancers
GB9203636D0 (en) * 1992-02-19 1992-04-08 Lucas Ind Plc Fuel pumping apparatus
KR0155015B1 (ko) * 1992-10-21 1998-12-01 고우야 마사시 2-아미노-1,3-프로판디올 화합물 및 면역 억제제
WO1994021642A1 (en) 1993-03-17 1994-09-29 Abbott Laboratories Macrocyclic amide and urea immunomodulators
US5590460A (en) * 1994-07-19 1997-01-07 Tessera, Inc. Method of making multilayer circuit
DE69524962T4 (de) 1994-08-22 2003-08-28 Mitsubishi Pharma Corp., Osaka Benzolderivate und deren medizinische verwendung
GB9521322D0 (en) 1995-10-17 1995-12-20 Sandoz Ltd Organic compounds
JPH11209277A (ja) 1998-01-19 1999-08-03 Yoshitomi Pharmaceut Ind Ltd 医薬組成物
GB9624038D0 (en) 1996-11-19 1997-01-08 Sandoz Ltd Organic compounds
ES2240868T3 (es) * 1997-04-04 2005-10-16 Mitsubishi Pharma Corporation Compuesto de 2-aminopropano -1,3-diol, su uso farmaceutico e intermedios en su sintesis.
GB9713730D0 (en) * 1997-06-30 1997-09-03 Ciba Geigy Ag Organic compounds
JP4627356B2 (ja) * 1999-06-30 2011-02-09 昭 松森 ウイルス性心筋炎の予防または治療薬剤
GB0003932D0 (en) 2000-02-18 2000-04-12 Novartis Ag Pharmaceutical compositions
JP2004523275A (ja) 2000-12-22 2004-08-05 アバンテク バスキュラー コーポレーション 治療能力のある薬剤の送達

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2108338C1 (ru) * 1991-09-09 1998-04-10 Мерк Энд Ко., Инк. Имидазолидильный макролид, или его изомеры, или его фармацевтически приемлемая соль, способы его получения и фармацевтическая композиция, обладающая иммунодепрессивной активностью

Also Published As

Publication number Publication date
MXPA04003738A (es) 2004-07-23
AU2002346859B2 (en) 2006-03-02
KR20090114483A (ko) 2009-11-03
CN1575173A (zh) 2005-02-02
HUP0402108A2 (hu) 2005-02-28
WO2003035068A1 (en) 2003-05-01
CN1307993C (zh) 2007-04-04
ECSP045086A (es) 2004-06-28
US7259170B2 (en) 2007-08-21
KR20040052250A (ko) 2004-06-22
CA2458690C (en) 2011-01-25
KR100978971B1 (ko) 2010-08-30
NZ532412A (en) 2006-01-27
AU2002346859C1 (en) 2008-07-10
PL368533A1 (en) 2005-04-04
ZA200401711B (en) 2004-10-21
CA2458690A1 (en) 2003-05-01
RU2004116067A (ru) 2005-04-20
NO20042074L (no) 2004-05-19
IL160973A0 (en) 2004-08-31
EP1439838A1 (en) 2004-07-28
HUP0402108A3 (en) 2008-02-28
BR0213463A (pt) 2004-11-09
US20040192716A1 (en) 2004-09-30
JP2005509634A (ja) 2005-04-14
GB0125443D0 (en) 2001-12-12

Similar Documents

Publication Publication Date Title
KR101178318B1 (ko) 효과적인 의약의 사용법 및 부작용 발현의 방어에 관한방법
CN1146411C (zh) 1,3-丙二醇衍生物的新用途
TWI250021B (en) Pharmaceutical composition for use in the treatment of an inflammatory autoimmune disease or condition
US20080015261A1 (en) Use of accelerated lymphocyte homing agents for the manufacture of a medicament for the treatment of delayed graft function
KR20120104422A (ko) 중추신경계 (cns) 자가면역 탈수초 질환의 치료 또는 예방을 위한 디아족사이드
JP2007262082A (ja) 多発性硬化症の処置のためのリルゾールの使用
KR101476451B1 (ko) 자가면역성 질환의 치료
CA2458690C (en) Pharmaceutical compositions comprising an ascomycin derivative
US20070219264A1 (en) Induction of immune tolerance
AU615745B2 (en) Method of effecting immunosuppression
AU2002346859A1 (en) Macrolides containing pharmaceutical compositions
WO1999015174A1 (en) Reverse prenyl compounds as immunosuppressants
JP2558147B2 (ja) 免疫性疾患治療剤
WO2025124501A1 (zh) 1-(3-氨基丙基)取代环状胺类化合物的用途
Fujita et al. Effect of the immunosuppressive agent, ciclosporin, on experimental immune complex glomerulonephritis in rats
CN122055146A (zh) Pde5抑制剂组合于促进神经突生长的新颖用途
JP2001508020A (ja) 多発性硬化症治療用のpde iv阻害剤
HK1060855B (en) Use of accelerated lymphocyte homing agents for the manufacture of a medicament for the treatment of delayed graft function
JPWO1994028893A1 (ja) 全身性自己免疫疾患又は炎症性神経疾患治療剤

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20131023