RU2284184C2 - Способ лечения рака - Google Patents
Способ лечения рака Download PDFInfo
- Publication number
- RU2284184C2 RU2284184C2 RU2003129527/14A RU2003129527A RU2284184C2 RU 2284184 C2 RU2284184 C2 RU 2284184C2 RU 2003129527/14 A RU2003129527/14 A RU 2003129527/14A RU 2003129527 A RU2003129527 A RU 2003129527A RU 2284184 C2 RU2284184 C2 RU 2284184C2
- Authority
- RU
- Russia
- Prior art keywords
- tegafur
- dose
- uracil
- day
- paclitaxel
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
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| US27357701P | 2001-03-06 | 2001-03-06 | |
| US60/273,577 | 2001-03-06 |
Publications (2)
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| RU2003129527A RU2003129527A (ru) | 2005-03-10 |
| RU2284184C2 true RU2284184C2 (ru) | 2006-09-27 |
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| RU2003129527/14A RU2284184C2 (ru) | 2001-03-06 | 2002-03-04 | Способ лечения рака |
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| JP (1) | JP2005506294A (enExample) |
| KR (1) | KR20030081496A (enExample) |
| BR (1) | BR0207443A (enExample) |
| CA (1) | CA2439676A1 (enExample) |
| CZ (1) | CZ20032266A3 (enExample) |
| EE (1) | EE200300429A (enExample) |
| HR (1) | HRP20030801A2 (enExample) |
| HU (1) | HUP0303466A3 (enExample) |
| IL (1) | IL157357A0 (enExample) |
| IS (1) | IS6925A (enExample) |
| MX (1) | MXPA03007989A (enExample) |
| NO (1) | NO20033910L (enExample) |
| PL (1) | PL363967A1 (enExample) |
| RU (1) | RU2284184C2 (enExample) |
| SK (1) | SK10602003A3 (enExample) |
| WO (1) | WO2002076459A1 (enExample) |
| YU (1) | YU69903A (enExample) |
| ZA (1) | ZA200306541B (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2440820C2 (ru) * | 2007-10-10 | 2012-01-27 | Унхва Корпорейшн | Противораковая композиция, включающая линию клеток, полученную из камбия и прокамбия стебля тисса (taxus) |
| RU2646450C1 (ru) * | 2017-05-11 | 2018-03-05 | Владимир Михайлович Курусин | Способ лечения предраковых и ранних стадий раковых заболеваний желудка |
| US11141421B2 (en) | 2018-01-29 | 2021-10-12 | Fujifilm Corporation | Antitumor agent for biliary tract cancer and method for treating biliary tract cancer |
| US11369625B2 (en) | 2016-08-31 | 2022-06-28 | Fujifilm Corporation | Anti-tumor agent, anti-tumor effect enhancer, and anti-tumor kit |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK287901B6 (sk) * | 2000-11-06 | 2012-03-02 | Pharma Mar, S. A. | Use of Ecteinascidin 743 for preparation of medicament for effective antitumor treatment |
| MXPA05009781A (es) | 2003-03-14 | 2005-10-26 | Taiho Pharmaceutical Co Ltd | Potenciador de efecto antitumoral y agente antitumoral. |
| WO2004087105A1 (en) * | 2003-04-02 | 2004-10-14 | Celator Pharmaceuticals, Inc. | Combination formulations of platinum agents and fluoropyrimidines |
| GB0312407D0 (en) * | 2003-05-29 | 2003-07-02 | Pharma Mar Sau | Treatment |
| CA2545054A1 (en) * | 2003-11-14 | 2005-06-02 | Pharma Mar, S.A. | Combination therapy comprising the use of et-743 and paclitaxel for treating cancer |
| GB0326486D0 (en) * | 2003-11-14 | 2003-12-17 | Pharma Mar Sau | Combination treatment |
| KR20050099311A (ko) * | 2004-04-09 | 2005-10-13 | 에이엔에이치 케어연구소(주) | 주사제용 항암제 조성물 |
| KR101287918B1 (ko) * | 2004-10-26 | 2013-07-19 | 오르토 바이오테크 프로덕츠 엘.피. | 엑티나시딘 ７４３과 조합된 페길화된 리포좀 독소루비신 |
| NZ554761A (en) | 2004-10-29 | 2010-01-29 | Pharma Mar Sa | Formulations comprising ecteinascidin and a disaccharide |
| US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| HUE038768T2 (hu) | 2005-02-18 | 2018-11-28 | Abraxis Bioscience Llc | Terápiás szerek kombinációi, valamint beadásukra szolgáló módszerek, és kombinációs terápia |
| GB0522082D0 (en) * | 2005-10-31 | 2005-12-07 | Pharma Mar Sa | Formulations |
| EP2201141A1 (en) * | 2007-10-19 | 2010-06-30 | Pharma Mar S.A. | Prognostic molecular markers for et-743 treatment |
| US9393318B2 (en) | 2010-03-29 | 2016-07-19 | Abraxis Bioscience, Llc | Methods of treating cancer |
| BR112012024590A2 (pt) | 2010-03-29 | 2016-05-31 | Abraxis Bioscience Inc | métodos de reforço da liberação de fármaco e da eficácia de agentes terapêuticos |
| KR20130088116A (ko) | 2010-06-04 | 2013-08-07 | 아브락시스 바이오사이언스, 엘엘씨 | 췌장암의 치료 방법 |
| KR102569221B1 (ko) * | 2015-04-22 | 2023-08-21 | 신-낫 프로덕츠 엔터프라이즈 엘엘씨 | 공결정 조성물 및 그의 약제학적 용도 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5A (en) * | 1836-08-10 | Thomas Blanchard | Machine for mortising solid wooden shells of ships' tackle-blocks | |
| RU2194541C1 (ru) * | 2001-07-13 | 2002-12-20 | Научно-исследовательский институт онкологии Томского научного центра СО РАН | Способ комбинированного лечения больных местнораспространенным раком желудка |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4328229A (en) | 1978-03-29 | 1982-05-04 | Taiho Pharmaceutical Company Limited | Anti-cancer composition for delivering 5-fluorouracil to cancer tissues |
| US5534513A (en) | 1991-09-05 | 1996-07-09 | Taiho Pharmaceutical Company, Ltd. | Antitumor potentiator and antitumor composition |
| FR2697752B1 (fr) * | 1992-11-10 | 1995-04-14 | Rhone Poulenc Rorer Sa | Compositions antitumorales contenant des dérivés du taxane. |
| US5919816A (en) * | 1994-11-14 | 1999-07-06 | Bionumerik Pharmaceuticals, Inc. | Formulations and methods of reducing toxicity of antineoplastic agents |
-
2002
- 2002-03-04 WO PCT/US2002/006262 patent/WO2002076459A1/en not_active Ceased
- 2002-03-04 JP JP2002574974A patent/JP2005506294A/ja active Pending
- 2002-03-04 HR HR20030801A patent/HRP20030801A2/hr not_active Application Discontinuation
- 2002-03-04 IL IL15735702A patent/IL157357A0/xx unknown
- 2002-03-04 MX MXPA03007989A patent/MXPA03007989A/es unknown
- 2002-03-04 SK SK10602003A patent/SK10602003A3/sk not_active Application Discontinuation
- 2002-03-04 CA CA002439676A patent/CA2439676A1/en not_active Abandoned
- 2002-03-04 HU HU0303466A patent/HUP0303466A3/hu unknown
- 2002-03-04 EE EEP200300429A patent/EE200300429A/xx unknown
- 2002-03-04 CZ CZ20032266A patent/CZ20032266A3/cs unknown
- 2002-03-04 YU YU69903A patent/YU69903A/sh unknown
- 2002-03-04 RU RU2003129527/14A patent/RU2284184C2/ru not_active IP Right Cessation
- 2002-03-04 US US10/090,354 patent/US6770653B2/en not_active Expired - Fee Related
- 2002-03-04 BR BR0207443-5A patent/BR0207443A/pt not_active IP Right Cessation
- 2002-03-04 KR KR10-2003-7011636A patent/KR20030081496A/ko not_active Withdrawn
- 2002-03-04 PL PL02363967A patent/PL363967A1/xx not_active Application Discontinuation
- 2002-03-04 EP EP02713715A patent/EP1368034A1/en not_active Withdrawn
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2003
- 2003-08-21 ZA ZA200306541A patent/ZA200306541B/xx unknown
- 2003-08-22 IS IS6925A patent/IS6925A/is unknown
- 2003-09-04 NO NO20033910A patent/NO20033910L/no not_active Application Discontinuation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5A (en) * | 1836-08-10 | Thomas Blanchard | Machine for mortising solid wooden shells of ships' tackle-blocks | |
| RU2194541C1 (ru) * | 2001-07-13 | 2002-12-20 | Научно-исследовательский институт онкологии Томского научного центра СО РАН | Способ комбинированного лечения больных местнораспространенным раком желудка |
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| abstract. Database CAPLUS Accession No 2000:103597, HOFF et al. Tegafur/uracil+calcium folinate in colorectal cancer: Double modulation of fluorouracil. Abstract, 1999, 58(3), pages 77-83. Database CAPLUS Accession No 2000:103599, BROCKSTEIN et al. Oral chemotherapy in head and neck cancer. Abstract, 1999, 58(3), pages 91-97. * |
| формула. * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2440820C2 (ru) * | 2007-10-10 | 2012-01-27 | Унхва Корпорейшн | Противораковая композиция, включающая линию клеток, полученную из камбия и прокамбия стебля тисса (taxus) |
| US11369625B2 (en) | 2016-08-31 | 2022-06-28 | Fujifilm Corporation | Anti-tumor agent, anti-tumor effect enhancer, and anti-tumor kit |
| RU2646450C1 (ru) * | 2017-05-11 | 2018-03-05 | Владимир Михайлович Курусин | Способ лечения предраковых и ранних стадий раковых заболеваний желудка |
| US11141421B2 (en) | 2018-01-29 | 2021-10-12 | Fujifilm Corporation | Antitumor agent for biliary tract cancer and method for treating biliary tract cancer |
Also Published As
| Publication number | Publication date |
|---|---|
| CZ20032266A3 (cs) | 2004-02-18 |
| US6770653B2 (en) | 2004-08-03 |
| US20020173482A1 (en) | 2002-11-21 |
| HUP0303466A3 (en) | 2005-02-28 |
| EP1368034A1 (en) | 2003-12-10 |
| IS6925A (is) | 2003-08-22 |
| RU2003129527A (ru) | 2005-03-10 |
| JP2005506294A (ja) | 2005-03-03 |
| ZA200306541B (en) | 2004-11-22 |
| IL157357A0 (en) | 2004-02-19 |
| CA2439676A1 (en) | 2002-10-03 |
| NO20033910L (no) | 2003-10-23 |
| MXPA03007989A (es) | 2003-12-04 |
| HRP20030801A2 (en) | 2004-08-31 |
| YU69903A (sh) | 2006-08-17 |
| PL363967A1 (en) | 2004-11-29 |
| KR20030081496A (ko) | 2003-10-17 |
| BR0207443A (pt) | 2004-04-06 |
| EE200300429A (et) | 2003-12-15 |
| SK10602003A3 (en) | 2004-10-05 |
| WO2002076459A1 (en) | 2002-10-03 |
| NO20033910D0 (no) | 2003-09-04 |
| HUP0303466A2 (hu) | 2004-01-28 |
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