RU2242985C2 - Stimulating agent of reproductive function and natural resistance in swine - Google Patents

Abstract

FIELD: animal science.

SUBSTANCE: the suggested stimulating agent is vitamin tincture prepared out of nettle leaves and mountain ash fruit at weight ratio being 3:7. The present preparation causes no allergic reactions and side effects.

EFFECT: higher reproductive function and natural resistance.

4 ex, 5 tbl

Description

The invention relates to animal husbandry, in particular to means that stimulate the reproductive function and natural resistance of animals, such as pigs.

Various stimulants of reproductive function and natural resistance of animals are known, including those based on the use of biologically active drugs (hormones, male pheromones, immune serums, antibiotics, tissue stimulants, etc.) [1].

The disadvantages of these stimulants include:

- the high cost of synthetic drugs;

- repeated use causes hypofunction of the endocrine glands;

- lack of effectiveness;

- they do not contribute to increasing the natural resistance of animals.

Also known is a stimulator of animal reproductive function - the drug pyroxan (6- [B- (3-phenyl-pyrrolidyl-1) -propionyl] -benzodioxan-1,4 hydrochloride), which helps to increase the fertility of animals [2].

The disadvantages of this tool are:

- high price;

- does not increase the natural resistance of animals.

The objective of the invention is to increase not only reproductive ability, but also the natural resistance of the body without possible harmful side effects by using affordable and cheap means of natural origin.

To solve this problem, a vitamin infusion prepared from nettle leaves and rowan fruits (hereinafter referred to as “infusion”) in a ratio by weight of 3: 7 was used as a stimulator of the reproductive function and immune system of animals. Nettle leaves contain vitamin C (0.1-0.2%), carotenoids: carotene (10 mg%), xanthophyll, xanthophyletoxide, viloxanthin, vitamin K (400 biological units), B1, pantothenic acid, protein substances, starch , formic acid, chlorophyll (up to 8%), iron salts, calcium, etc. The chlorophyll contained in the leaves has the ability to enhance metabolism, increase the contractility of smooth muscles of the uterus and intestines, accelerate the regeneration of damaged tissues, and normalize the reproductive cycle. Vitamins and iron salts contained in nettles normalize lipid metabolism in the body.

Rowan fruits contain vitamin P (1.2-1.9%), vitamin C (40-200 mg%), vitamin B ₁ (0.5 μg / g), B ₂ (0.1-0.3 μg / g), carotenoids (1.2-5.7 mg%), as well as vitamins K and E; organic acids (citric, L-malic, d-tartaric), trace elements, glucose, fructose, L-idit (sorbite), L-sorbose (total sugar about 8.6%) [3].

The infusion consists of 3 parts of dry chopped nettle leaves and 7 parts of dried rowan fruits. A tablespoon of the mixture was poured with 2 glasses of boiling water, boiled for 10 minutes, insisted in tightly sealed dishes and in a cool room for 4 hours; filtered through cheesecloth and given to sows orally.

The experiments were carried out on pregnant (25 days before farrowing) sows of large white breed at the age of the 3rd farrowing. Watering was carried out daily 3 times a day before feeding 200 ml for 20 days.

Sows were given infusion precisely in the last period of gestation (3 weeks before farrowing) because in this period the indicators of homeostasis are most variable under the influence of external factors. And the physiological state of the body (including the immune system) of females before farrowing affects the quality of colostrum (the accumulation of antibodies, nutrients, vitamins, etc. in it occurs mainly before farrowing), and the usefulness of colostrum, in turn, affects viability of piglets in the early postembryonic period.

Example 1. In the sows of the experimental group, receiving vitamin infusion 3 times a day, 200 ml for 20 days before farrowing, an increase in reproductive ability was observed - the duration of farrowing was reduced by 15.8 minutes (presumably due to an increase in the contractility of the uterine myometrium) , multiple pregnancy increased by 0.9 piglets, embryonic mortality decreased by 75% compared with the uterus of the control group (Table 1).

Example 2. Also established a positive effect of this drug on the viability of piglets in the early postembryonic period. Thus, the incidence of young animals (up to 3 weeks of age) obtained from the uterus of the experimental groups was 35.1% lower than in the control, and, accordingly, the percentage of death of piglets decreased from 20.8 to 7% (Table 2) .

Example 3. Piglets obtained from sows of the experimental and control groups were monitored immediately prior to weaning at 2 months of age. It was revealed that the infusion contributed not only to increase the reproductive function of the uterus itself, but also to the safety, as well as the growth rate of young animals up to 2 months. So, the safety of piglets in the experimental group was 91.4%, while in the control - 79.2%. The live weight of piglets in the experimental group was equal to 18.1 ± 0.93 kg compared with 15.5 ± 0.58 kg (table. 3). Presumably, a higher growth rate of young animals under the influence of the drug is associated with their increased viability and lower incidence. This indicates a better development of their immune defense mechanisms in the early postembryonic period compared to piglets in the control group. The obtained data can be explained by the presence of a significant amount of vitamins and other biologically active substances in the nettle leaves and rowan fruits, among which vitamins A and C are of crucial importance for the formation of the body's defenses in young animals and stimulation of natural resistance in adult animals.

Example 4. The positive effect of the infusion on the reproductive ability of sows and the viability of piglets coincides with the improvement of a number of hematological, biochemical and immunological parameters of their blood. In particular, the sows of the experimental groups and piglets obtained from them showed a higher content of hemoglobin, glucose, vitamins A and C in the blood (within the physiological norm). The biologically active substances of nettle and mountain ash have a stimulating effect on the general reactivity of the body, strengthen non-specific defense mechanisms (phagocytic activity of leukocytes) and promote the production of antibodies, accelerate the formation and development of their own resistance in piglets in the early postnatal period (Tables 4 and 5).

The proposed stimulator of reproductive function and natural resistance is a tool of natural origin, prepared from affordable, cheap and environmentally friendly raw materials, has no side effects for the body. Its use allows you to:

- effectively increase the reproductive function and natural resistance of animals;

- to exclude a specific effect on the animal organism and, therefore, the occurrence of stress and allergic reactions and other side effects.

- exclude significant costs for the purchase and administration of drugs.

Sources of information taken into account during the examination

1. Guskov A.M., Darius G.S. Biotechnology. - Chisinau: AIR, 1993 - p.104-117.

2. Patent No. 2177688, class A 01 K 67/02, A 61 K 31/44 - prototype.

3. Rabinovich M.I. Medicinal plants in veterinary practice: a Handbook. - M .: Agropromizdat, 1987 .-- p.104-206.

Claims (1)

Stimulator of reproductive function and natural resistance of animals in the form of a vitamin infusion, characterized in that the vitamin infusion is prepared from nettle leaves and rowan fruits in a weight ratio of 3: 7.