RU2209089C2 - Method for recovery of disinfecting agent - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: invention relates to agents used for treatment and disinfection of articles and equipment of medicinal designation and can be used for recovery disinfecting agent where concentration of peracetic acid is diminished with time. Method involves addition of 35% hydrogen peroxide solution taken in the amount 9.0-16.0 mole per 1 l of the parent disinfecting agent with its fitness time running out and where the content of peracetic acid is reduced significantly. Prepared mixture is kept for 3-6 days up to recovery of the parent concentration of peracetic acid. EFFECT: prolonged fitness time of disinfecting agent. 1 tbl

Description

 The invention relates to medicine, namely to means for processing and disinfecting medical devices and equipment, and can be used to restore a disinfectant, in which the concentration of peracetic acid decreases over time.

 A disinfectant is known (SU 1333338, A 61 L 2/16, priority 20.06.83). It contains, wt.%: Peracetic acid 12.5-13.3%; citylpyridinium chloride 13.3-18.75; sodium sulfate 18.75-20 and water - the rest. The tool has a relatively low disinfectant activity.

A known method of obtaining a disinfectant preparation (SU 1755802, A 61 L 2/16, priority 02.21.90). The method includes mixing a solution of stabilized 50% hydrogen peroxide with a mixture of acetic anhydride and sulfuric acid at 26-30 ^o C for 5-6 hours. The solution is left to stand for 10-12 hours. Then add a stabilizer and water.

 Known means for sterilization and laundering of biological fluids (RU 2077890, A 61 L 2/16, priority 04/27/97). It contains peracetic acid (NAA), hydrogen peroxide, acetic acid, ethylenediaminetetraacetic acid and water, taken in certain quantitative proportions.

 The tool is obtained by mixing an aqueous solution of ethylenediaminetetraacetic acid with glacial acetic acid, followed by the addition of the remaining components to the indicated concentrations.

 The inventions described above make it possible to obtain disinfectants with a relatively short shelf life of the drug, after which the agent does not have the necessary activity and, as a rule, must be disposed of.

 The problem to which the invention is directed, is to increase the shelf life of the disinfectant by restoring the concentration of the active substance.

 The problem is solved as follows.

 A method of restoring a disinfectant containing peracetic acid and hydrogen peroxide is characterized in that an additional 35% hydrogen peroxide is added in an amount of 9.0-16.0 mol per 1 liter of disinfectant and incubated for 3-6 days until the concentration of peracetic acid is restored .

 Peracetic acid (NAA) is widely used as a disinfectant in the food industry and medicine, so it is very important to have a constant stable concentration of NAA in the product. The content of NUK in the finished disinfectant may be from 5% to 30%. The shelf life of such drugs while maintaining high stabilizing qualities can be up to one year. However, by the end of the shelf life of the product, the content of the NUK in it is significantly reduced. This fact negatively affects the possibility of further use of the product and practically leads to its disposal.

 The restoration of the concentration of NAA is as follows. First, determine the concentration of the product, the expiration date of which is near the end, or has expired. The recovery process is carried out by 35% hydrogen peroxide. The required amount of peroxide is determined and added to the initial composition and the process of restoring the concentration of NAA is conducted for several days until the initial concentration of NAA is restored. 35% hydrogen peroxide is introduced in an amount of 9.0-16.0 mol per 1 liter of the original disinfectant. The resulting mixture was incubated for 3-6 days until the restoration of the concentration of NAA, close to the original.

 Examples of the method.

 Example 1

 The disinfectant contains hydrogen peroxide - 26%, NAA - 5.5%. After a year of storage of this drug, a control check showed that the product contains hydrogen peroxide - 15%, NAA - 2%. To restore the activity of the disinfectant, 10.3 mol of 35% hydrogen peroxide per liter of product is added to it. The resulting mixture was incubated for 3 days. The control check showed that the resulting product contains hydrogen peroxide - 22%, NAA - 5.5%.

 Example 2

 The disinfectant contains hydrogen peroxide - 18%, NAA - 15%. After a year of storage of this drug, a control check showed that the product contains hydrogen peroxide - 7%, IAA - 6%. To restore the activity of the disinfectant, 15.4 mol of 35% hydrogen peroxide per liter of product is added to it. The resulting mixture was incubated for 5 days. A control check showed that the resulting product contains hydrogen peroxide - 18%, NUK - 12%.

 The table shows the activity data of the reconstituted disinfectant.

 As the results show, when exposed to a disinfectant with a restored concentration of NAA, the drug has the same activity as the original one.

 The present invention will find application as a method of restoring a highly effective disinfectant and extending its shelf life.

Claims (1)

 A method of restoring a disinfectant containing peracetic acid and hydrogen peroxide, characterized in that an additional 35% hydrogen peroxide is added in an amount of 9.0-16.0 mol per 1 liter of disinfectant and incubated for 3-6 days until concentration is restored peracetic acid.

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