RU2204373C1 - Method for treating the cases of bacterial vaginosis - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: method involves applying vaginal irrigation procedures at 36-38 C using mineral water of general mineralization of 8.2- 8.6 g/dm³. The irrigations are done slowly during 10-15 min with 1.0-1.5 l of natural mineral water per one procedure. The total course is 4-12 procedures long when applied daily or every other day with the natural mineral water taken as a drink at a dose of 150-200 ml three times a day. EFFECT: eliminated adverse side effects of treatment; enhanced effectiveness of treatment.

Description

 The invention relates to medicine, namely to gynecology, and can be used to treat bacterial vaginosis.

 There is a method of treating bacterial vaginosis using drugs of metronidazole or dalacin C, and then eubiotics (Kira E.F. Treatment of bacterial vaginosis // Akush. And gin.- 1993.- 5. -S. 39-41).

 Disadvantages: frequent relapses of bacterial vaginosis.

The prototype of the proposed method is: vaginal irrigation with bromide water. One procedure consumes from 6 to 8-10 l, temperature 36-38 ^o C, the duration of irrigation 6-8-10 minutes According to indications, water with a salinity of from 24 to 36 g / l and from 36 to 70 g / l is used. (Methods of treatment at the resort of Ust-Kachka. Ed. By Prof. Tuev A.V. et al., Perm, 2001, p. 28).

 Disadvantages: the presence of side effects: a large amount of bromide water, supplied under strong pressure, washes out not only conditionally pathogenic, but also the normal microflora of the vagina, thereby creating the prerequisites for the development of vaginal dysbiosis.

 The invention is aimed at solving problems: eliminating side effects with high efficiency of the method, expanding the range of natural remedies for the treatment of bacterial vaginosis.

These tasks are achieved through the use of drinking mineral water (PMV) "Ustkachkinskaya 1/99" with a total mineralization of 8.2-8.8 g / dm ³ in the form of ingestion and local irrigation. Gynecological irrigation is carried out slowly at 1-1.5 liters per procedure at t 36-38 ^o C, the duration of 10-15 minutes, a course of 4-12 procedures daily or every other day. Admission PMV "Ustkachkinskaya 1/99" inside 3 times a day for 150-200 ml.

Ustkachkinskaya well water 1/99, depth 47.0 m with a total salinity of 8.2-8.6 g / dm ³ refers to the average saline sulphate-chloride calcium-sodium water (Cl 57-60, S0 ₄ 38-43, Na 65 -72, Ca 21-22 mg • equiv.%). In terms of mineralization and the ratio of the main macrocomponents, it is close to the Ergeninsky type (GOST 13273-88, group XVII).

 Mineral water wells N 1/99 is recommended for drinking treatment at the resort; industrial bottling of this water as a canteen is also possible.

 This sulfate-chloride calcium-sodium mineral water is indicated for drinking treatment of diseases of the digestive system; endocrine system diseases, nutritional disorders and metabolic disorders.

 There are no data on the use of Ustkachkinskaya 1/99 mineral water for the treatment of bacterial vaginosis.

The method is as follows. The patient is prescribed gynecological irrigation PMV "Ustkachkinskaya 1/99" with a total salinity of 8.2-8.6 g / dm ³ of 1.0-1.5 liters per procedure at t 36-38 ^o C for 10-15 minutes , daily or every other day, with a break on menstruation days, the number of procedures is 4-12. Irrigation is carried out slowly, without pressure of water, using an upgraded Esmarch mug with a metering device. At the same time, an oral administration of Ustkachkinskaya 1/99 is prescribed 3 times a day, 150-200 ml at t 37-38 ^o C for 20-40 minutes before eating.

Case Studies
Example 1
Patient T., turned 12.2001 about complaints of leucorrhoea due to unpleasant odor, local discomfort.

 When viewed in the mirrors: the absence of signs of inflammation (the mucous membrane of the vagina is normal pink); profuse leucorrhoea of liquid consistency, white color; Aminotest with 10% KOH solution is positive.

 In the smear: white blood cells more than 50 in sight, mixed flora, single fungi; degree of purity IV.

Analysis dated 12/19/2001: no lactobacilli were detected, bifidobacteria 10 ⁴ CFU / swab, lactic streptococcus 10 ⁵ , Corynebaсterium pseudodyphterificum 4 • 10 ⁵ , B. subfilis 1 • 10 ⁴ , S. sociiii / urealytiсum 2 • 10 ⁴ CFU / tampon.

 Diagnosis: bacterial vaginosis. Endometriosis in the presence of chronic endometritis.

4 irrigation procedures of the vaginal mucosa PMV "Ustkachkinskaya 1/99" were carried out, with a total mineralization of 8.2-8.6 g / dm ³ , slowly using 1-1.5 L of PMV at t 36-38 ^o C for 10 min , daily, and at the same time taking PMV "Ustkachkinskaya 1/99" inside of 150-200 ml 3 times a day for 4 days.

 At the reception 12/25/2001: no complaints; when viewed in the mirrors - the absence of signs of inflammation, light, slight, odorless discharge, negative aminotest. In the smear - single leukocytes, mixed flora.

Analysis dated December 25, 2001: lactobacilli 10 ⁵ , bifidobacteria 10 ⁴ CFU / swab, lactic streptococcus 10 ⁵ , Corynebacterium pseudodyphterificum 9 • 10 ³ , Str.equinus 6 • 10 ⁴ CFU / swab.

Example 2
Patient R., complaints of leucorrhoea, often about an unpleasant odor, local discomfort.

 When viewed in the mirrors: the absence of signs of inflammation (mucous membrane of the vagina of physiological color); profuse leucorrhoea of liquid consistency, yellowish color; Aminotest with 10% KOH solution is positive.

 In the smear: white blood cells up to 10 in the field of view, mixed flora, purity IV.

Analysis dated 12/19/2001: lactobacilli 10 ⁵ KOH / swab, no bifidobacteria were detected, lactic streptococcus was not detected, Miorocoscus spp 3 • 10 ² , S.epidermidis 1 • 10 ² CFU / swab.

 Diagnosis: bacterial vaginosis. Chronic endometritis on the background of the IUD.

5 irrigation procedures of the vaginal mucosa PMV "Ustkachkinskaya 1/99", with a total mineralization of 8.2-8.6 g / dm ³ , slowly, for 15 minutes, daily, at t 36-38 ^o C, using 1.5 l PMV, and at the same time taking PMV "Ustkachkinskaya 1/99" inside of 150-200 ml 3 times a day for 5 days.

 At the reception 12/25/2001: no complaints; when viewed in the mirrors - the absence of signs of inflammation, light, slight, odorless discharge, negative aminotest. In the smear - single leukocytes, mixed flora, purity III.

Analysis dated 12.25.2001: lactobacilli 10 ⁵ CFU / swab, bifidobacteria 10 ⁴ , lactic streptococcus 10 ⁵ , Miсroccus spp. 3 • 10 ² , CFU / swab.

Example 3
Patient V., complaints of discharge with an unpleasant "fishy" smell, local discomfort.

 When viewed in the mirrors: the absence of signs of inflammation (the mucous membrane of the vagina is normal pink); profuse leucorrhoea of liquid consistency, white color; Aminotest with 10% KOH solution is positive.

 In the smear: single white blood cells (up to 10 in the field of view), coccobacillary flora; degree of purity IV.

Analysis dated 12/20/2001: lactobacilli 10 ³ CFU / swab, bifidobacteria 10 ⁴ , lactic streptococcus 10 ³ , Bas. Cereus 3 • 10 ⁶ , S.epidermidis 4 • 10, Ochrobactrum anthropi 1.7 • 10 ⁶ CFU / swab , Candida albicans 1 • 10 ⁴ CFU / swab.

 Diagnosis: bacterial vaginosis.

5 irrigation procedures of the vaginal mucosa PMV "Ustkachkinskaya 1/99" with a total mineralization of 8.2-8.6 1g / ldm ^{3 were} performed, slowly, for 15 minutes, daily, using 1.0-1.5 l of PMV at t 36- 38%, and at the same time taking PMV "Ustkachkinskaya 1/99" inside of 150-200 ml 3 times a day, for 5 days.

 At the reception on December 25, 2001, the patient made no complaints, when examined in the mirrors, there were no signs of inflammation, slight, odorless discharge, the aminotest was negative. In the smear - single leukocytes, mixed flora, purity III.

Analysis dated December 25, 2001: lactobacilli 10 ³ CFU / swab, bifidobacteria 10 ⁴ , lactic streptococcus 10 ⁵ , S. epidermidis 4 • 10 ⁵ , Ochrobactrum anthropi 1.7 • 10 ⁶ , Str.parauberis 1.1 • 10 ⁶ CFU / swab.

 The application of the proposed method can prevent side effects, since the slow feed rate of mineral water allows you to mechanically wash out the conditionally pathogenic flora, to a lesser extent affecting the normal microflora, more strongly adhered to the epithelial cells. The method is simple, avoids the use of drugs, allows you to simultaneously treat diseases of the stomach and intestines, has a high therapeutic activity.

Claims (1)

A method of treating bacterial vaginosis by vaginal irrigation with mineral water at t 36-38 ^o C, characterized in that drinking mineral water "Ustkachkinskaya 1/99" with a total salinity of 8.2-8.6 g / dm ³ is used as mineral water moreover, irrigation is carried out slowly for 10-15 minutes, using 1.0-1.5 L of PMV for one procedure, a course of 4-12 procedures daily or every other day, with simultaneous intake of PMV "Ustkachkinskaya 1/99" of 150-200 ml 3 times a day.