RU2147808C1 - Biologically active food additive - Google Patents

Abstract

FIELD: food industry. SUBSTANCE: biologically active food additive from oil-bearing raw material is a product of cedar seeds treatment with content, mas. pts: phospholipids, not less 0.36; triaceglycerides, not less 5.7; proteins, not less 20; tocopherol, not less 7.64 mg per 100 g of product. The additive may additionally have apiculture products, wheat germs, biologically-active product (mumiyo) and algae. EFFECT: increased total unspecific resistance of organism. 4 cl, 7 ex

Description

 The claimed invention relates to the oil and fat and food industries, but more specifically relates to a biologically active food supplement, which can be used as a general strengthening effect for rational and therapeutic nutrition, including various pathological conditions caused by general weakening of the body, for enrichment of diets for adults and children with vitamins, minerals.

 Currently, many biologically active food additives have been developed containing products that are concentrates of natural or identical to natural biologically active substances obtained by processing plant or animal raw materials by chemical or biotechnological methods using traditional, alternative or special technology, and intended for direct administration with food or introduction to specialized foods in order to enrich the diet with individual nutrients and / or biologically active substances or their complex.

 The patent PN 2098985 describes a biologically active food supplement based on honey (not less than 48 wt.%), Containing, in addition, cedar oil (5.4 wt.%), A shell of cedar seeds (20.4 wt.%), cake seeds of cedar seeds (12.8 wt.%), Rhodiola rosea root powder (5.7 wt.%), Leuzea root powder (5.7 wt.%), sea buckthorn oil (2.3 wt.%).

 In the composition protected by RF patent N 2098985, the active substance is honey, both due to the quantitative presence and the content of useful substances in it, which has a therapeutic effect. Further, the biological activity of the known additives, in addition to honey, is provided by sea buckthorn oil, rhizomes and roots of Rhodiola rosea and Leuzea, belonging to the class of medicinal plants. It is these ingredients that determine the effectiveness of this supplement in relation to the effect on the state of the body's immune system and its hematological parameters.

 The cedar oil, cake seeds of cedar seeds (5.4 and 12.8 wt.%, Respectively) and 20 wt.% Shells of cedar seeds present in the additive in a relatively small amount act as fillers and binders that affect organoleptic and physico-chemical characteristics biologically active additives, but not on its parapharmacological properties. At the same time, the supplement, despite the undoubted advantages of a biologically active drug, due to the extremely high honey content can only be highly recommended to most of the population.

 There are many biologically active food additives that contribute to the restoration and maintenance of the physiological functions inherent in a healthy body, containing complexes of substances obtained artificially. So, in Hungarian patent N 176203 MKI: A 61 K 9/08, a biologically active food supplement is described, containing a strictly defined ratio of two electrolytes (sodium, potassium) and eleven trace elements (magnesium, iron, zinc, copper, manganese, nickel, boron , cobalt, molybdenum, vanadium, fluorine) associated with six organic substances (glycerin, glycine, EDTA, 1 - (+) - tartaric acid, succinic stone acid, 1 - (+) -ascorbic acid) and water at the following ratio of components, g / l: sodium 0.64, potassium 0.28, magnesium 0.41, iron 2.01, zinc 1.14, copper 0.25, manganese 0.31, nor kel 0.11, boron 0.11, cobalt 0.03, molybdenum 0.19, vanadium 0.12, fluorine 0.09, glycerol 6.00, glycine 2.30, EDTA 2.34, 1 - (+) - tartaric acid 1.56, succinic acid 0.50, 1 - (+) - ascorbic acid 0.30, water up to 1000.0.

 This additive provides the prevention and treatment of various pathological conditions associated with a deficiency of balanced microelementary homeostasis, however, it contains trace elements with high oxidative activity, but there are no antioxidants when this additive is introduced into food products, their shelf life is significantly reduced, exactly as the term their possible use. In addition, the introduction into the body of additives and products obtained synthetically and artificially, but not contained in the natural organic complex, leads to slagging of the body, since it does not completely process them.

 Also known is a biologically active food supplement based on a natural product - plant materials - ginseng (40-60 wt.%), Containing, in addition, apilak (dry native royal jelly of working bees) in an amount of 0.55-0.70 wt. % and retinol acetate (vitamin A) in an amount of 0.04-0.05 wt.%, as well as alpha-tocopherol acetate (vitamin E) in an amount of 0.45-0.60 wt.% (RF patent N 2057463 MKI: A 23 L 1/29).

 Ginseng is known as a source of a huge amount of biologically active substances, which determine its many-sided effect on the human body. So, panaxin tones up the activity of the heart and blood vessels, panaxic acid affects oxidative processes, involving fats in the metabolism, panaquilone stimulates the endocrine system and helps maintain the necessary level of hormones in the body, essential oil has an analgesic effect, calms the nervous system, ginsenin glycoside affects the regulation of carbohydrate metabolism, reduces the concentration of sugar in the blood and increases the synthesis of glycogen. Ginseng also contains vitamins of groups C, B1 and B2, minerals in the form of manganese and iron.

 Apilak is a complex and rich composition of the product of the vital activity of bees, each component of which has powerful biologically active properties. The antimicrobial activity of apilak is known, its stimulating effect on the reproductive system of the body. Under the action of apilak, an increase in the nonspecific defense of the body is manifested. Vitamins A, E and Apilak harmoniously complement the stimulating effect of ginseng. The use of the described additive provides a pronounced tonic effect and a clear positive dynamics of the main clinical symptoms, increased performance, resistance to physical activity, stabilization of the emotional background, a decrease in the clinical manifestations of asthenic syndrome, a decrease in the frequency and intensity of muscular-articular pain syndrome, and an improvement in gastrointestinal tract function.

 However, despite the indicated high effectiveness of such an additive, its use is unsafe, since an overdose can cause serious disturbances in the body due to the high activity of components, including synthesized vitamins A and E, the presence of which does not achieve the natural harmony of the complementarity of vitamins and microelements .

 The closest analogue is a biologically active food supplement based on oilseed raw materials such as sunflower, namely Vitol supplement (see Conference Abstracts, Krasnodar, 06/26/98).

 The basis of the claimed invention is the task of expanding the range of biologically active additives from oilseeds, with hypolipidemic, hypocholesterolemic properties that can increase the overall nonspecific resistance of the body.

 This problem is solved when creating a biologically active food supplement from oilseeds, which according to the invention is a product of processing cedar seeds with a content, wt. share%: phospholipids not less than 0.36; triacylglycerides of at least 5.7; no less than 20 proteins; tocopherol at least 7.64 mg / 100 g of product.

 Thanks to the invention, it has become possible to create a biologically active food supplement from oilseeds with a wide range of therapeutic and prophylactic effects — hypolipidemic, hypocholesterolemic properties, which can increase the general nonspecific resistance of the body.

 The greatest nutritional and pharmacological value of a biologically active food supplement is achieved, according to the invention, provided that as a product of the processing of cedar seeds it contains a product of processing of cedar seeds, subjected to counting.

 According to the invention, it is most expedient that, as a product of processing cedar seeds, a biologically active food supplement contain cake and / or meal of cedar seed kernels, which allows to reduce the cost of food additives and use cedar kernels without waste.

 To increase the nutritional value and expand the pharmacological action of a biologically active food supplement, it is advisable, according to the invention, that it additionally contains at least one substance selected from the group comprising the beekeeping product, wheat germ embryos, mummies, algae.

 Further objectives and advantages of the claimed invention will become apparent from the following detailed description of the biologically active food supplement and specific examples of this supplement.

 The biologically active food supplement proposed in the claimed invention contains mainly from 50 to 99.1 wt.% Cedar seed product. Speaking about the product of processing cedar seeds, we mainly mean crushed cedar seed kernels, oilcake or meal of cedar seed kernels. In this case, the biologically active food supplement may additionally contain cedar oil (in small amounts) or cedar oil itself. It is the natural chemical composition of the kernel of cedar seeds that determines the high nutritional and pharmacological value of the claimed additives. To achieve the greatest nutritional and pharmacological value of the claimed additives, it is advisable to use cedar seeds collected from trees subjected to medium intensity counting for an average of no more than 9 years. (Tapping is a violation of the root leaf connection of a tree).

 According to the invention, the biologically active food supplement contains a cedar seed processing product having mainly the following characteristics.

Chemical indicators
nitrogen-containing substances, abs.% dry matter:
total nitrogen - 2.90
protein - 2.61
non-protein - 0.29
total nitrogen fat-free residue
abs.% dry matter - 7.70
protein - 4.83
non-protein - 0.70
solid residue nitrogen, 2.17
(protein - 20.0 wt.%
Free amino acids, mg abs.% Dry matter
cystine - 10.5
lysine - 15.3
histidine - 17.1
arginine - 15.5
aspartic acid - 23.3
serine - 9.8
glycine - 4.5
glutamic acid - 50.3
threonine - 16.7
Alanine - 30.7
proline - 24.1
tyrosine - 17.3
methionine - 13.4
valine - 8.4
tryptophan - traces
phenylalanine - 13.5
leucine-isoleucine - 14.2
Bound amino acids (protein amino acids)
lysine - 1.2
histidine - 0.9
arginine - 5.9
aspartic acid - 4.9
threonine - 1.0
serine - 2.1
glutamic acid - 4.6
proline - 1.6
glycine - 1.7
Alanine - 1.9
valine - 1.1
methionine - 0.6
isoleucine - 1.6
leucine - 2.0
tyrosine - 1.5
phenylalanine - 1.4
tryptophan - 0.6
Carbon components, abs.% Dry matter
polysaccharides:
fiber - 2.2
starch - 4,5
dextrin - 2.3
pentosans - 1.8
amount of soluble
carbohydrates: - 6.2
sucrose - 5.1
raffinose - 3.4
glucose - 0.1
fructose - 0.2
Lipids
fat content 64.0% in abs. dry matter, the content of phospholipids 4.4% in abs. dry matter and triacylglycerides 46.9% in abs. dry matter.

Minerals (phosphorus-iron, mg%; manganese-silver, mg / kg)
phosphorus - 481.8
magnesium - 529.4
potassium - 489.3
sodium - 107.1
calcium - 48.4
iron - 2.3
Manganese - 5.4
copper - 1.5
zinc - 12.1
molybdenum - 0.2
silicon - 2,3
aluminum - 5.3
iodine - 0.5
Boron - 0,0002
nickel - 0.03
cobalt - 0.05
lead - 0.03
strontium - 0,0004
silver - 0.03
ash content,% - 2.5
Vitamins
vitamin E (tocopherols, including α-tocopherol, β-tocopherol, γ-tocopherol) 24-30 mg / 100 g of the core;
Group B vitamin, including vitamin B1 (thiamine) - 0.2-0.4 mg / 100 g of the core,
vitamin B2 (riboflavin) -1.326 mg abs.% dry matter;
Vitamin C (ascorbic acid) 14.0 mg abs.% dry matter;
Vitamin A (carotene) 0.47 mg% abs. dry matter;
vitamin P (linoleic and linolenic acids) - 69.7-51.2% abs. dry matter.

Lipoids
the content of phosphatides 1.3-1.65%
Oilcake and meal of the cedar seed kernel is a product formed during the extraction or extraction of the cedar seed kernel in order to obtain cedar oil. It was established that the meal of cedar seed kernels has almost the same elementary composition as the core. The mass fraction of valuable food components in the cake / meal prevails compared to the core, since in the process of obtaining vegetable oil they remain in the cake / meal. The amount of essential amino acids in the cake / meal is on average 171.1 mg / 100 g abs. Dry. substances, and the content of readily soluble carbohydrates is approximately 18.8% on abs. dry substance. The composition of the lipids contained in the meal / meal includes phospholipids (0.36 wt.%), Triacylglycerides (5.7 wt.%); 11 fatty acids were identified in the fatty acid composition, including linoleic, linolenic, oleic, arachidonic.

The chemical composition of oilcake, meal of cedar seeds kernel, wt. share%:
solids - 94.2
including:
fat - 18.0 and less
protein - 45.0
carbohydrates - 28.8 (of which starch 35%)
ash - 5.42
vitamins, mg / 100 g - 12.86
including:
group B - 0.42
tocopherols - 7.64
Thus, oilcake and meal as processed products of the kernel of cedar seeds are highly valuable natural products.

 It is also known that proteins, as the main part of a living organism, play a large role in human life. They take an active part in the formation of enzymes, hormones, antibodies. The nutritional value of proteins can be largely judged by the amino acid composition, since there is a correlation between the amino acid composition of proteins and their biological value. In the chemical evaluation of a particular protein, the content of essential amino acids is compared with that of chicken egg, which has the most favorable amino acid ratio for anabolism. As can be seen from the above, in terms of the balance of most essential amino acids, the total protein of cedar seeds is close to that of chicken eggs. When evaluating cedar seed proteins, the amino acid composition of its protein complex was compared with the optimal standard of the essential amino acids FAO / WHO - the Joint Expert Group of the Organization for Nutrition and Agriculture and the World Health Organization: cedar seed proteins approach the FAO sample in terms of isoleucine, exceed it in threonine, valine, leucine, phenylalanine, tyrosine, tryptophan.

In relation to the daily human need, the content of amino acids in the seeds of cedar is,%:
isoleucine - 280
leucine - 434
lysine - 219
phenylalanine - 364
methionine - 98
threonine - 317
tryptophan - 278
valine - 257,
thus, cedar seeds and, accordingly, their processed products have high nutritional value.

 In accordance with the claimed invention, it is advisable to mainly use the products of the processing of cedar seeds, subjected to medium intensity counting, which causes quite profound changes in biochemical processes in the plant, affecting its growth and development, some botanical properties, changes in its organomineral complex and the pharmacological effect of the products on it basis.

 The inventive biologically active food supplement based on such seed processing products of such a cedar provides an increase in the general nonspecific resistance of the body, helps to increase the body's resistance to physical stress, achieved by introducing balanced amino acid components into the body; the lipid-lowering and hypocholesterolemic effect of the claimed additives is due to the content of an effective amount of phospholipids and triacylglycerides. In addition, the natural combination of the ingredients of the seeds of such a cedar and products of their processing is adequate to the complex process of healing, strengthening and even healing the body.

 Based on the foregoing, it is clear that the claimed biologically active food supplement has, in addition to high nutritional value, and high pharmacological value - with systematic use, the claimed supplement is able to protect a person from a number of diseases, increase his working capacity, increase longevity, have a positive effect in the treatment of arteriosclerosis, kidney diseases, in pathological conditions accompanied by high blood pressure, when a compact and nutritious plant food is required, When bessolnoy diet when there is a loss of appetite, nervous disorders; a good effect is observed when using the inventive supplement with increased acidity of the stomach, with gastric ulcer and 12 duodenal ulcer.

 The inventive biologically active food supplement, in addition to cedar seed processing products, may contain at least one substance selected among the following: starch, beekeeping product, wheat germ embryos, mummy, underwater plant products, immunocorrectors, cytomedine-based biostimulants. Speaking about beekeeping products, we mean propolis, honey, apilak, which, as part of the claimed supplement, can act as a binder, biologically active component, being an additional source of multivitamins, micro and macro elements and amino acids.

 The germ of wheat germ is a valuable protein and vitamin concentrate - they contain more than 40% of vegetable protein with all the essential amino acids, up to 40% of carbohydrates (starch, sugar), more than 25% of lipids, consisting of polyunsaturated fatty acids (linoleic, linolenic and others). In addition, wheat germ embryos contain water-soluble vitamins B1, B2, B6, and H, and PP, pantothenic, folic acid, and fat-soluble vitamins: A and E, as well as 21 mineral elements, which are essential for the normal functioning of the human body.

 The presence in the inventive biologically active food supplement of starch and / or embryos of wheat germ allows you to give and save the dosage form in the form of tablets, granules, dragees and others.

 Speaking of underwater plant products, we have in mind mainly marine herbs, for example, seaweed kelp, sea grass zoster or alga Shirullinae platencis.

 The presence in the claimed biologically active food supplement of a substance / substances selected from the above allows achieving new bi-directional biological effects due to the biological activity of the additional substance present, however, the pronounced nutritional and pharmacological effect of the additive is in accordance with the seed processing products cedar, which are the basis of this supplement.

 A biologically active food additive pressed into a tablet or granule may have a surface coating of pharmaceutically used glaze, including chocolate.

 The following examples in no way limit the scope of protection of the claimed invention, but are given only for the purpose of illustrating it.

 Example 1

 A biologically active food supplement in the form of a tablet weighing 0.5 - 3.0 g, coated with chocolate-based glaze, contains 70 wt.% Cake of cedar seed kernels, subjected to tapping, which provides a violation of the root leaves of the tree, 20.1 wt.% Crushed kernels of cedar seeds, subjected to tapping, and 0.9 wt.% rice starch.

 Example 2

 A dietary supplement in the form of a tablet weighing 0.5-3.0 g, coated with glaze, contains 87 wt.% Cedar seed kernel cake, similar to that indicated in Example 1, 11.7 wt.% Crushed cedar seed kernel, subjected to counting 0.2 wt. % cedar oil made from cedar seeds, subjected to counting, and 1.1 wt.% rice starch.

 Example 3

 A dietary supplement in the form of a tablet weighing 0.5-3.0 g coated with powdered sugar contains 69.0% by weight of cedar seed kernel cake, similar to that described in Example 1, 10.9% by weight of crushed cedar seeds , similar to that specified in example 1, and 20.1 wt.% the germ of wheat germ (in powder form).

 Example 4

 A biologically active food supplement in the form of a glazed dragee weighing 0.5-1.0 g contains 50 wt.% Cake of cedar seed kernel, similar to that specified in example 1, 1.0 wt.% Bee propolis and 49.0 wt.% Algae (in the form of a powder).

 Example 5

 A biologically active food supplement in the form of a tablet weighing 0.5 - 3.0 g contains 65.0 wt.% Cake (meal) of the kernel of cedar seeds, similar to that specified in example 1, 34 wt. % seaweed kelp, 1.0 wt.% rice starch.

 Example 6

 A dietary supplement in the form of a tablet weighing 0.5 - 3.0 g contains cedar seed kernels, 1.0 wt.% Mummy and 1.0 wt.% Rice starch.

 Example 7

 A biologically active food supplement in the form of a glazed dragee weighing 0.5 - 3.0 g contains 98.5 wt.% Cake (meal) of the kernel of cedar seeds, similar to that described in example 1, and 1.5 wt.% Rice starch.

 Since the components of the biologically active food supplement specified in Examples 1-7 are widely known and used food products, no adverse reactions to the intake of such a supplement were observed. The composition of the claimed additives belongs to the group of practically harmless formulations and can be used for a long time, since it does not exceed the physiological needs of the body.

 The claimed invention allowed to create a biologically active food supplement from oilseeds, rich in natural physiologically balanced nutrient and biologically active substances, which determines a wide range of therapeutic and prophylactic effects of the additive.

Claims (4)

 1. Biologically active food supplement from oilseeds, characterized in that it is a product of processing cedar seeds with a content, wt. share%: phospholipids - not less than 0.36, triacylglycerides - not less than 5.7, proteins - not less than 20, tocopherol - not less than 7.64 mg / 100 g of product.  2. Biologically active food supplement according to claim 1, characterized in that, as a product of processing cedar seeds, it contains a product of processing cedar seeds, subjected to counting.  3. Biologically active food supplement according to claim 1 or 2, characterized in that as a product of the processing of cedar seeds, it contains cake and / or meal of cedar seeds.  4. Biologically active food supplement according to claim 1 or 2, characterized in that it further comprises at least one substance selected from the group comprising the beekeeping product, germ of wheat germ, mummy, algae.