RU2019128164A - Адъюванты на масляной основе - Google Patents
Адъюванты на масляной основе Download PDFInfo
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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Claims (12)
1. Вакцинная композиция, содержащая антиген вируса Нипах и/или вируса Хендра и адъювантную композицию, где указанная вакцинная композиция содержит масляную фазу, присутствующую в количестве, по меньшей мере, 36% об./об. от указанной вакцинной композиции, иммуностимулирующий олигонуклеотид и поликатионный носитель, и при этом указанная вакцинная композиция представляет собой эмульсию вода-в-масле.
2. Вакцинная композиция по п. 1, где масляная фаза присутствует в количестве по меньшей мере 45% композиции по объему.
3. Вакцинная композиция по п. 1, где масляная фаза присутствует в количестве по меньшей мере 48% композиции по объему.
4. Вакцинная композиция по п. 1, где масляная фаза присутствует в количестве по меньшей мере 50% композиции по объему.
5. Вакцинная композиция по какому-либо одному из пп. 1-4, где иммуностимулирующий олигонуклеотид представляет собой CpG, и поликатионный носитель представляет собой декстран DEAE.
6. Вакцинная композиция по какому-либо одному из пп. 1-5, где антиген представляет собой растворимый протеин G Хендра.
7. Вакцинная композиция по п. 1-6, где антиген присутствует в количестве 50-200 мкг на дозу.
8. Вакцинная композиция по п. 7, где антиген присутствует в количестве приблизительно 100 мкг на дозу.
9. Применение вакцинной композиции по какому-либо одному из пп. 1-8 для лечения или предупреждения инфекции Хендра у субъекта.
10. Применение по п. 9, где субъект представляет собой лошадь.
11. Применение вакцинной композиции по какому-либо одному из пп. 1-8 для лечения или предупреждения инфекции Нипаха у субъекта.
12. Применение по п. 11, где субъект представляет собой свинью.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361879959P | 2013-09-19 | 2013-09-19 | |
| US61/879,959 | 2013-09-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016109925A Division RU2730011C2 (ru) | 2013-09-19 | 2014-09-19 | Адъюванты на масляной основе |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2019128164A true RU2019128164A (ru) | 2019-10-10 |
| RU2816851C2 RU2816851C2 (ru) | 2024-04-05 |
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