RU2019102154A3 - - Google Patents
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- Publication number
- RU2019102154A3 RU2019102154A3 RU2019102154A RU2019102154A RU2019102154A3 RU 2019102154 A3 RU2019102154 A3 RU 2019102154A3 RU 2019102154 A RU2019102154 A RU 2019102154A RU 2019102154 A RU2019102154 A RU 2019102154A RU 2019102154 A3 RU2019102154 A3 RU 2019102154A3
- Authority
- RU
- Russia
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16189150.2 | 2016-09-16 | ||
EP16189150 | 2016-09-16 | ||
PCT/EP2017/001101 WO2018050286A1 (en) | 2016-09-16 | 2017-09-18 | Traf 6 inhibitors |
Publications (3)
Publication Number | Publication Date |
---|---|
RU2019102154A RU2019102154A (ru) | 2020-10-16 |
RU2019102154A3 true RU2019102154A3 (ru) | 2021-01-22 |
RU2770404C2 RU2770404C2 (ru) | 2022-04-15 |
Family
ID=56939925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2019102154A RU2770404C2 (ru) | 2016-09-16 | 2017-09-18 | Ингибиторы traf 6 |
Country Status (8)
Country | Link |
---|---|
US (2) | US10669278B2 (ru) |
EP (1) | EP3512852A1 (ru) |
JP (1) | JP7117293B2 (ru) |
CN (1) | CN109715631B (ru) |
AU (1) | AU2017326116B2 (ru) |
CA (1) | CA3032210A1 (ru) |
RU (1) | RU2770404C2 (ru) |
WO (1) | WO2018050286A1 (ru) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109715631B (zh) * | 2016-09-16 | 2022-02-18 | 德国亥姆霍兹慕尼黑中心健康与环境研究中心(有限公司) | Traf 6抑制剂 |
US20210017183A1 (en) * | 2018-03-22 | 2021-01-21 | Helmholtz Zentrum Munchen - Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Traf 6 inhibitors |
WO2020252487A1 (en) * | 2019-06-14 | 2020-12-17 | Children's Hospital Medical Center | Rational therapeutic targeting of oncogenic immune signaling states in myeloid malignancies via the ubiquitin conjugating enzyme ube2n |
WO2023150793A1 (en) * | 2022-02-07 | 2023-08-10 | Cornell University | Inhibitors of malic enzyme 1 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE424402T1 (de) * | 2005-03-21 | 2009-03-15 | Lilly Co Eli | Imidazopyridinverbindungen |
MX2007014377A (es) | 2005-05-17 | 2008-02-06 | Plexxikon Inc | Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina. |
BRPI0611863B1 (pt) * | 2005-06-22 | 2021-11-23 | Plexxikon, Inc | Composto, bem como composição e kit compreendendo o mesmo, composto intermediário na preparação do mesmo, método para tratamento e uso do mesmo |
US20110021513A1 (en) * | 2006-09-07 | 2011-01-27 | Biogen Idec Ma Inc. | Modulators of interleukin-1 receptor-associated kinase |
JP2010511018A (ja) | 2006-12-01 | 2010-04-08 | ガラパゴス・ナムローゼ・フェンノートシャップ | 変性疾患及び炎症性疾患の治療に有用なトリアゾロピリジン化合物 |
KR20100128305A (ko) * | 2008-02-28 | 2010-12-07 | 노파르티스 아게 | C-met 티로신 키나제 매개 질환의 치료를 위한 이미다조[1,2-b]피리다진 유도체 |
WO2011160016A2 (en) | 2010-06-17 | 2011-12-22 | The Trustees Of Columbia University In The City Of New York | E3 binding pockets and identification and use of e3 ligase inhibitors |
CN109715631B (zh) * | 2016-09-16 | 2022-02-18 | 德国亥姆霍兹慕尼黑中心健康与环境研究中心(有限公司) | Traf 6抑制剂 |
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2017
- 2017-09-18 CN CN201780057311.3A patent/CN109715631B/zh active Active
- 2017-09-18 EP EP17784840.5A patent/EP3512852A1/en active Pending
- 2017-09-18 JP JP2019514813A patent/JP7117293B2/ja active Active
- 2017-09-18 CA CA3032210A patent/CA3032210A1/en active Pending
- 2017-09-18 WO PCT/EP2017/001101 patent/WO2018050286A1/en unknown
- 2017-09-18 AU AU2017326116A patent/AU2017326116B2/en active Active
- 2017-09-18 RU RU2019102154A patent/RU2770404C2/ru active
- 2017-09-18 US US16/333,913 patent/US10669278B2/en active Active
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2020
- 2020-03-09 US US16/812,691 patent/US11001591B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2018050286A1 (en) | 2018-03-22 |
CN109715631A (zh) | 2019-05-03 |
US10669278B2 (en) | 2020-06-02 |
AU2017326116A1 (en) | 2019-02-07 |
JP2019531289A (ja) | 2019-10-31 |
US20190211025A1 (en) | 2019-07-11 |
AU2017326116B2 (en) | 2020-10-22 |
US20200277297A1 (en) | 2020-09-03 |
CN109715631B (zh) | 2022-02-18 |
US11001591B2 (en) | 2021-05-11 |
RU2770404C2 (ru) | 2022-04-15 |
CA3032210A1 (en) | 2018-03-22 |
JP7117293B2 (ja) | 2022-08-12 |
RU2019102154A (ru) | 2020-10-16 |
EP3512852A1 (en) | 2019-07-24 |