RU2018131440A3 - - Google Patents

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Publication number
RU2018131440A3
RU2018131440A3 RU2018131440A RU2018131440A RU2018131440A3 RU 2018131440 A3 RU2018131440 A3 RU 2018131440A3 RU 2018131440 A RU2018131440 A RU 2018131440A RU 2018131440 A RU2018131440 A RU 2018131440A RU 2018131440 A3 RU2018131440 A3 RU 2018131440A3
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RU
Russia
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RU2018131440A
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Russian (ru)
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RU2018131440A (ru
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Publication of RU2018131440A publication Critical patent/RU2018131440A/ru
Publication of RU2018131440A3 publication Critical patent/RU2018131440A3/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mechanical Engineering (AREA)
  • Composite Materials (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2018131440A 2016-03-23 2017-03-23 Антагонисты FimH, являющиеся производными маннозы, пригодные для лечения заболевания RU2018131440A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662312017P 2016-03-23 2016-03-23
US62/312,017 2016-03-23
PCT/US2017/023764 WO2017165619A1 (en) 2016-03-23 2017-03-23 Mannose-derived antagonists of fimh useful for treating disease

Publications (2)

Publication Number Publication Date
RU2018131440A RU2018131440A (ru) 2020-04-23
RU2018131440A3 true RU2018131440A3 (https=) 2020-05-18

Family

ID=59900869

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018131440A RU2018131440A (ru) 2016-03-23 2017-03-23 Антагонисты FimH, являющиеся производными маннозы, пригодные для лечения заболевания

Country Status (10)

Country Link
US (3) US10738070B2 (https=)
EP (1) EP3432892A4 (https=)
JP (1) JP2019509315A (https=)
KR (1) KR20180128937A (https=)
CN (1) CN108778288A (https=)
AU (1) AU2017238392A1 (https=)
BR (1) BR112018069147A2 (https=)
CA (1) CA3018345A1 (https=)
RU (1) RU2018131440A (https=)
WO (1) WO2017165619A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019509315A (ja) 2016-03-23 2019-04-04 フィンブリオン セラピューティックス, インコーポレイテッドFimbrion Therapeutics, Inc. 疾患の処置に有用なFimHのマンノース由来アンタゴニスト
US10385087B1 (en) * 2018-04-26 2019-08-20 National Taipei University Of Technology Xylose derivatives and process for preparation thereof
TWI821328B (zh) 2018-07-10 2023-11-11 英商葛蘭素史克智慧財產發展有限公司 新穎化合物
US12297223B2 (en) 2019-05-07 2025-05-13 Glaxosmithkline Intellectual Property Development Limited Compounds
US12351597B2 (en) 2019-06-19 2025-07-08 Glaxosmithkline Intellectual Property Development Limited Substituted biphenyl or phenylheteroaryl-mannosides as antagonists of FimH
CN111205344B (zh) * 2020-01-14 2023-03-14 华东理工大学 一种用于甲醇溶剂识别的纯有机磷光小分子材料及其制备方法
CN113461753B (zh) * 2020-03-31 2023-05-23 郑计岳 2-炔基甘露糖衍生物及其应用
CN111518738B (zh) * 2020-05-08 2022-02-08 徐州海润生物科技有限公司 重组卡介苗及其制备方法和应用
CN113797212B (zh) * 2020-06-11 2023-12-22 兰州大学 一组含有甘露糖结构的抗菌药物的合成方法及活性研究
CN116621891B (zh) * 2023-05-25 2023-10-31 齐齐哈尔医学院 白鲜酚苷c及其制备方法和其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5122602A (en) 1989-02-13 1992-06-16 Miles Inc. Chromogenic merocyanine enzyme substrates
JPH09505309A (ja) 1993-11-18 1997-05-27 ワシントン・ユニバーシティ 細菌感染の治療および予防のための化合物および医薬組成物
US6420127B1 (en) 1994-11-18 2002-07-16 Washington University Compounds and pharmaceutical compositions for the treatment and prophylaxis of bacterial infections
AU7470300A (en) 1999-08-11 2001-03-05 Washington University Anti-bacterial compounds directed against pilus biogenesis, adhesion and activity; co-crystals of pilus subunits and methods of use thereof
US6719991B2 (en) 2000-06-09 2004-04-13 Baylor College Of Medicine Combination of antimicrobial agents and bacterial interference to coat medical devices
US7265245B2 (en) 2003-10-08 2007-09-04 Innovaprotean, S.L Compounds useful for the treatment of diseases associated with the formation of amyloid fibrils
US20080171706A1 (en) 2004-03-23 2008-07-17 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Anti-Adhesive Compounds to Prevent and Treat Bacterial Infections
SE528382C2 (sv) 2004-10-05 2006-10-31 Probi Ab Probiotiska lactobacillusstammar för förbättrad vaginal hälsa
FR2876798A1 (fr) 2004-10-14 2006-04-21 Univ Clermont Auvergne Diagnostic et traitement de la maladie de crohn
WO2011050323A1 (en) 2009-10-22 2011-04-28 The Washington University Compounds and methods for treating bacterial infections
WO2012109263A1 (en) 2011-02-07 2012-08-16 The Washington University Mannoside compounds and methods of use thereof
NZ601176A (en) * 2009-12-14 2014-03-28 Univ Basel Mannose derivatives as antagonists of bacterial adhesion
WO2012164074A1 (en) 2011-06-03 2012-12-06 University Of Basel Mannose phosphate derivatives as antagonists of bacterial adhesion
MX2015012472A (es) 2013-03-12 2016-02-10 Vertex Pharma Derivados de manosa para el tratamiento de infecciones bacterianas.
CN111423479A (zh) 2013-05-30 2020-07-17 华盛顿大学 用于治疗细菌性感染的化合物和方法
US20200002303A1 (en) 2016-03-11 2020-01-02 Fimbrion Therapeutics, Inc. C-glycoside compounds useful for treating disease
JP2019509315A (ja) 2016-03-23 2019-04-04 フィンブリオン セラピューティックス, インコーポレイテッドFimbrion Therapeutics, Inc. 疾患の処置に有用なFimHのマンノース由来アンタゴニスト

Also Published As

Publication number Publication date
EP3432892A4 (en) 2019-10-30
BR112018069147A2 (pt) 2019-01-22
EP3432892A1 (en) 2019-01-30
US20190106451A1 (en) 2019-04-11
KR20180128937A (ko) 2018-12-04
CN108778288A (zh) 2018-11-09
US10738070B2 (en) 2020-08-11
WO2017165619A1 (en) 2017-09-28
JP2019509315A (ja) 2019-04-04
CA3018345A1 (en) 2017-09-28
US20250009723A1 (en) 2025-01-09
US20200407390A1 (en) 2020-12-31
AU2017238392A1 (en) 2018-09-27
RU2018131440A (ru) 2020-04-23

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FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20210225