RU2018107502A - METHOD FOR PRODUCING A THYROTHROPIC AND ANTIOXIDANT ACTIVITY - Google Patents

METHOD FOR PRODUCING A THYROTHROPIC AND ANTIOXIDANT ACTIVITY Download PDF

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Publication number
RU2018107502A
RU2018107502A RU2018107502A RU2018107502A RU2018107502A RU 2018107502 A RU2018107502 A RU 2018107502A RU 2018107502 A RU2018107502 A RU 2018107502A RU 2018107502 A RU2018107502 A RU 2018107502A RU 2018107502 A RU2018107502 A RU 2018107502A
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RU
Russia
Prior art keywords
leaves
aerial parts
antioxidant activity
mill
ground
Prior art date
Application number
RU2018107502A
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Russian (ru)
Other versions
RU2018107502A3 (en
RU2707300C2 (en
Inventor
Александр Константинович Лобанов
Константин Александрович Лобанов
Владимир Федорович Корсун
Елена Владимировна Корсун
Светлана Валерьевна Тишковец
Янина Геннадьевна Разуваева
Анюта Алексеевна Торопова
Татьяна Владимировна Корнопольцева
Александр Гаврилович Мондодоев
Сергей Матвеевич Николаев
Original Assignee
Александр Константинович Лобанов
Константин Александрович Лобанов
Владимир Федорович Корсун
Елена Владимировна Корсун
Светлана Валерьевна Тишковец
Янина Геннадьевна Разуваева
Анюта Алексеевна Торопова
Татьяна Владимировна Корнопольцева
Александр Гаврилович Мондодоев
Сергей Матвеевич Николаев
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Александр Константинович Лобанов, Константин Александрович Лобанов, Владимир Федорович Корсун, Елена Владимировна Корсун, Светлана Валерьевна Тишковец, Янина Геннадьевна Разуваева, Анюта Алексеевна Торопова, Татьяна Владимировна Корнопольцева, Александр Гаврилович Мондодоев, Сергей Матвеевич Николаев filed Critical Александр Константинович Лобанов
Priority to RU2018107502A priority Critical patent/RU2707300C2/en
Publication of RU2018107502A publication Critical patent/RU2018107502A/en
Publication of RU2018107502A3 publication Critical patent/RU2018107502A3/ru
Application granted granted Critical
Publication of RU2707300C2 publication Critical patent/RU2707300C2/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/52—Juglandaceae (Walnut family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Cosmetics (AREA)

Claims (1)

Способ получения лекарственного средства, обладающего тиреотропной и антиоксидантной активностью, представляющего собой сухой экстракт, состоящий из следующего растительного сырья в соотношении: листьев грецкого ореха 18%, листа лещины 16%, листьев репешка 15%, надземной части череды 14%, надземной части дурнишника колючего 12%, листьев крапивы 8%, надземной части ряски 7%, корней цикория 5%, надземной части татарника 5%, которые измельчают на мельнице до размера частиц не более 2 мм и экстрагируют 65% этиловым спиртом трижды в соотношении сырье-экстрагент, равном 1:16 при температуре 60°С и постоянном перемешивании, после чего объединенные извлечения упаривают, очищают сепарированием, высушивают в вакуумной сушилке при температуре 60°С и измельчают на мельнице пропеллерного типа.A method of obtaining a medicinal product with thyrotropic and antioxidant activity, which is a dry extract, consisting of the following plant materials in the ratio: walnut leaves 18%, hazel leaves 16%, burlap leaves 15%, aerial parts of a string of 14%, aerial parts of thorny thorn 12%, nettle leaves 8%, aerial parts of duckweed 7%, chicory roots 5%, aerial parts of tatarnar 5%, which are ground in a mill to a particle size of no more than 2 mm and extracted with 65% ethyl alcohol three times in the ratio of raw-ext agent equal to 1:16 at a temperature of 60 ° C and constant stirring, after which the combined extract evaporated and purified by separation, dried in a vacuum oven at 60 ° C and ground in the mill, propeller type.
RU2018107502A 2018-02-28 2018-02-28 Method of producing drug having thyrotropic and antioxidant activity RU2707300C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2018107502A RU2707300C2 (en) 2018-02-28 2018-02-28 Method of producing drug having thyrotropic and antioxidant activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2018107502A RU2707300C2 (en) 2018-02-28 2018-02-28 Method of producing drug having thyrotropic and antioxidant activity

Publications (3)

Publication Number Publication Date
RU2018107502A true RU2018107502A (en) 2019-08-30
RU2018107502A3 RU2018107502A3 (en) 2019-10-24
RU2707300C2 RU2707300C2 (en) 2019-11-26

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Family Applications (1)

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RU2018107502A RU2707300C2 (en) 2018-02-28 2018-02-28 Method of producing drug having thyrotropic and antioxidant activity

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RU (1) RU2707300C2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2747482C1 (en) * 2020-09-04 2021-05-05 Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Method for quantifying amount of flavonoids in walnut leaves

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2314120C1 (en) * 2006-05-02 2008-01-10 Закрытое акционерное общество "Эвалар" Curative-cosmetic composition for external using for normalization of thyroid tissue structure
RU2333764C1 (en) * 2007-05-15 2008-09-20 Павел Иванович Мешков Medicine for treatment and prevention of thyroid gland diseases
RU2446815C1 (en) * 2011-03-03 2012-04-10 Общество С Ограниченной Ответственностью "Парафарм" Biologically active food additive used for normalising thyroid function
RU2482863C1 (en) * 2012-02-15 2013-05-27 Наталья Владимировна Полуконова Method for preparing dry extract of herbal raw material possessing biological activity
RU2574028C1 (en) * 2014-12-12 2016-01-27 Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт лекарственных и ароматических растений" (ФГБНУ ВИЛАР) Method for producing dry refined extract of european bugleweed herb exhibiting thyreotropic action
RU2619863C1 (en) * 2016-03-28 2017-05-18 Ирина Геннадьевна Николаева Method for producing agents with thyroid-stimulating activity

Also Published As

Publication number Publication date
RU2018107502A3 (en) 2019-10-24
RU2707300C2 (en) 2019-11-26

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Effective date: 20200229