RU2017142710A - Состав полиинозиновой-полицитидиловой кислоты (поли-(i:с)) на основе горохового крахмала для профилактики и/или лечения инфекций верхних дыхательных путей - Google Patents
Состав полиинозиновой-полицитидиловой кислоты (поли-(i:с)) на основе горохового крахмала для профилактики и/или лечения инфекций верхних дыхательных путей Download PDFInfo
- Publication number
- RU2017142710A RU2017142710A RU2017142710A RU2017142710A RU2017142710A RU 2017142710 A RU2017142710 A RU 2017142710A RU 2017142710 A RU2017142710 A RU 2017142710A RU 2017142710 A RU2017142710 A RU 2017142710A RU 2017142710 A RU2017142710 A RU 2017142710A
- Authority
- RU
- Russia
- Prior art keywords
- composition
- microparticles
- microparticle
- starch
- patient
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 43
- 229940115272 polyinosinic:polycytidylic acid Drugs 0.000 title claims 20
- 230000002265 prevention Effects 0.000 title claims 10
- 239000002253 acid Substances 0.000 title claims 5
- 208000015181 infectious disease Diseases 0.000 title claims 4
- 230000000241 respiratory effect Effects 0.000 title 1
- 239000011859 microparticle Substances 0.000 claims 40
- 229920002472 Starch Polymers 0.000 claims 16
- 239000008107 starch Substances 0.000 claims 16
- 235000019698 starch Nutrition 0.000 claims 16
- 238000000034 method Methods 0.000 claims 15
- 208000036142 Viral infection Diseases 0.000 claims 13
- 230000009385 viral infection Effects 0.000 claims 13
- 210000002345 respiratory system Anatomy 0.000 claims 9
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 241000430519 Human rhinovirus sp. Species 0.000 claims 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- 206010022000 influenza Diseases 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 206010062106 Respiratory tract infection viral Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 229920000881 Modified starch Polymers 0.000 claims 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000002953 phosphate buffered saline Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L3/00—Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
- C08L3/02—Starch; Degradation products thereof, e.g. dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Polymers & Plastics (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15167129.4 | 2015-05-11 | ||
| EP15167129 | 2015-05-11 | ||
| PCT/IB2016/000890 WO2016181226A1 (en) | 2015-05-11 | 2016-05-10 | Polyinosinic-polycytidylic acid (poly(i:c)) pea starch formulation for the prevention and/or treatment of upper respiratory tract infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2017142710A true RU2017142710A (ru) | 2019-06-11 |
Family
ID=53174864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017142710A RU2017142710A (ru) | 2015-05-11 | 2016-05-10 | Состав полиинозиновой-полицитидиловой кислоты (поли-(i:с)) на основе горохового крахмала для профилактики и/или лечения инфекций верхних дыхательных путей |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20180353533A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3294268A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2018515530A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20180004233A (cg-RX-API-DMAC7.html) |
| CN (1) | CN107820423A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016259869A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2983659A1 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1251926A1 (cg-RX-API-DMAC7.html) |
| MA (1) | MA44384A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2017142710A (cg-RX-API-DMAC7.html) |
| TW (1) | TW201705963A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016181226A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3824896A4 (en) * | 2018-07-20 | 2022-08-24 | Shiseido Company, Ltd. | VIRUS INACTIVATION AGENT |
| CU20200110A7 (es) * | 2020-12-23 | 2022-08-09 | Ct Ingenieria Genetica Biotecnologia | Péptidos para el tratamiento de infecciones respiratorias de origen viral |
| KR102451861B1 (ko) | 2021-03-09 | 2022-10-07 | 주식회사 오라팜 | 급성 호흡기 바이러스 및 로타바이러스 감염 질환 예방 및 치료를 위한 조성물 |
| KR102439760B1 (ko) | 2021-03-09 | 2022-09-02 | 주식회사 오라팜 | 상기도 감염균 질환 예방 및 치료를 위한 조성물 |
| CN114917242A (zh) * | 2022-05-31 | 2022-08-19 | 复旦大学附属中山医院 | 合成双链rna类似物经滴鼻预防呼吸道传播病毒的应用及其用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5707644A (en) * | 1989-11-04 | 1998-01-13 | Danbiosyst Uk Limited | Small particle compositions for intranasal drug delivery |
| CN101229378A (zh) * | 2005-05-05 | 2008-07-30 | 国家淀粉及化学投资控股公司 | 用于送递活性剂的组合物 |
| JP2009209086A (ja) * | 2008-03-04 | 2009-09-17 | Masami Moriyama | 粘膜投与型ワクチン |
| CN101757018A (zh) * | 2008-12-24 | 2010-06-30 | 天津瑞普生物技术股份有限公司 | 一种用于畜禽的聚肌胞干粉及其制备方法 |
| CN102988303A (zh) * | 2011-09-15 | 2013-03-27 | 天津泽世德生物医药有限公司 | 一种多聚肌苷酸多聚胞苷酸冻干粉针的制备方法 |
| SG11201406208QA (en) * | 2012-05-03 | 2014-11-27 | Janssen Sciences Ireland Uc | Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections |
| US10409943B2 (en) * | 2013-09-03 | 2019-09-10 | Synopsys, Inc. | Efficient analog layout prototyping by layout reuse with routing preservation |
| RU2016117398A (ru) * | 2013-11-06 | 2017-12-11 | Янссен Сайенсиз Айрлэнд Юси | Композиции полиинозиновой-полицитидиловой кислоты (поли (и:ц)) для лечения инфекций верхних дыхательных путей |
-
2016
- 2016-05-10 CN CN201680040346.1A patent/CN107820423A/zh active Pending
- 2016-05-10 WO PCT/IB2016/000890 patent/WO2016181226A1/en not_active Ceased
- 2016-05-10 AU AU2016259869A patent/AU2016259869A1/en not_active Abandoned
- 2016-05-10 EP EP16753457.7A patent/EP3294268A1/en not_active Withdrawn
- 2016-05-10 KR KR1020177035145A patent/KR20180004233A/ko not_active Withdrawn
- 2016-05-10 US US15/573,227 patent/US20180353533A1/en not_active Abandoned
- 2016-05-10 RU RU2017142710A patent/RU2017142710A/ru not_active Application Discontinuation
- 2016-05-10 JP JP2017559086A patent/JP2018515530A/ja active Pending
- 2016-05-10 CA CA2983659A patent/CA2983659A1/en not_active Abandoned
- 2016-05-10 MA MA044384A patent/MA44384A/fr unknown
- 2016-05-10 HK HK18111254.8A patent/HK1251926A1/zh unknown
- 2016-05-11 TW TW105114594A patent/TW201705963A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2983659A1 (en) | 2016-11-17 |
| WO2016181226A1 (en) | 2016-11-17 |
| JP2018515530A (ja) | 2018-06-14 |
| AU2016259869A1 (en) | 2017-11-30 |
| HK1251926A1 (zh) | 2019-05-03 |
| MA44384A (fr) | 2019-01-23 |
| KR20180004233A (ko) | 2018-01-10 |
| CN107820423A (zh) | 2018-03-20 |
| US20180353533A1 (en) | 2018-12-13 |
| TW201705963A (zh) | 2017-02-16 |
| EP3294268A1 (en) | 2018-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20201208 |