RU2017126030A3 - - Google Patents
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- RU2017126030A3 RU2017126030A3 RU2017126030A RU2017126030A RU2017126030A3 RU 2017126030 A3 RU2017126030 A3 RU 2017126030A3 RU 2017126030 A RU2017126030 A RU 2017126030A RU 2017126030 A RU2017126030 A RU 2017126030A RU 2017126030 A3 RU2017126030 A3 RU 2017126030A3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/17—Newcastle disease virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
- C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10071—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18171—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/34—Vector systems having a special element relevant for transcription being a transcription initiation element
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14200340 | 2014-12-24 | ||
| EP14200340.9 | 2014-12-24 | ||
| PCT/EP2015/081121 WO2016102647A1 (en) | 2014-12-24 | 2015-12-23 | Improved hvt-vectored nd-ibd vaccine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2017126030A RU2017126030A (ru) | 2019-01-24 |
| RU2017126030A3 true RU2017126030A3 (ru) | 2019-01-24 |
| RU2692013C2 RU2692013C2 (ru) | 2019-06-19 |
Family
ID=52282550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017126030A RU2692013C2 (ru) | 2014-12-24 | 2015-12-23 | Улучшенная вакцина против nd-ibd на основе вектора hvt |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10308956B2 (ru) |
| EP (1) | EP3185899B1 (ru) |
| JP (1) | JP6246985B1 (ru) |
| CN (1) | CN107002097B (ru) |
| AR (1) | AR103245A1 (ru) |
| BR (1) | BR112017013595A2 (ru) |
| ES (1) | ES2648672T3 (ru) |
| HU (1) | HUE035364T2 (ru) |
| MX (1) | MX2017008504A (ru) |
| PL (1) | PL3185899T3 (ru) |
| RU (1) | RU2692013C2 (ru) |
| WO (1) | WO2016102647A1 (ru) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11596687B2 (en) | 2016-06-17 | 2023-03-07 | Intervet Inc. | Recombinant non-pathogenic Marek's disease virus constructs encoding infectious laryngotracheitis virus and infectious bursal disease virus antigens |
| ES2936117T3 (es) | 2016-12-14 | 2023-03-14 | Boehringer Ingelheim Animal Health Usa Inc | Vectores recombinantes de VHT que expresan múltiples antígenos de patógenos aviares y vacunas que los comprenden |
| CN107099513B (zh) * | 2017-06-22 | 2020-07-14 | 北京邦卓生物科技有限公司 | 一种共表达ndv hn和ibdv vp2基因的hvt的构建及其应用 |
| US11229698B2 (en) | 2017-10-12 | 2022-01-25 | Intervet Inc. | Recombinant non-pathogenic Marek's Disease virus constructs encoding multiple heterologous antigens |
| WO2019121888A1 (en) | 2017-12-20 | 2019-06-27 | Intervet International B.V. | Improved diluent for cell-associated alphaherpesvirus vaccine |
| CN109320594B (zh) * | 2018-11-13 | 2021-09-28 | 四川大学 | 一种禽传染性支气管炎和新城疫的病毒样颗粒、制备方法及应用 |
| CN110331135A (zh) * | 2019-07-18 | 2019-10-15 | 扬州大学 | 表达基因vii型新城疫病毒融合蛋白的重组火鸡疱疹病毒候选疫苗株及制备方法 |
| KR20220056241A (ko) | 2019-09-11 | 2022-05-04 | 조에티스 서비시즈 엘엘씨 | 조류 병원체의 항원을 발현하는 재조합 칠면조 헤르페스바이러스 벡터 및 이의 용도 |
| MX2022007579A (es) | 2019-12-20 | 2022-07-19 | Intervet Int Bv | Vacuna de vector hvt multivalente. |
| MX2022016337A (es) | 2020-06-17 | 2023-04-10 | Boehringer Ingelheim Vetmedica Gmbh | Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogenicas, su produccion y usos. |
| MX2023002674A (es) | 2020-09-07 | 2023-04-03 | Intervet Int Bv | Vacuna del tallo de ha para blancos positivos a anticuerpos ha. |
| CN112501139B (zh) * | 2020-12-11 | 2023-03-21 | 新乡学院 | 一株重组新城疫病毒毒株及其制备方法和应用 |
| US20240058436A1 (en) | 2020-12-24 | 2024-02-22 | Intervet Inc. | Multivalent hvt vector vaccine |
| WO2023213946A1 (en) | 2022-05-05 | 2023-11-09 | Intervet International B.V. | New multivalent hvt vector vaccine |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5928648A (en) | 1985-09-06 | 1999-07-27 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
| US5961982A (en) | 1985-09-06 | 1999-10-05 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
| US5965138A (en) | 1985-09-06 | 1999-10-12 | Syntro Corporation | Recombinant chimeric virus and uses thereof |
| WO1987004463A1 (en) * | 1986-01-27 | 1987-07-30 | Syntro Corporation | Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccine containing same |
| GB8603341D0 (en) | 1986-02-11 | 1986-03-19 | Portapax Ltd | Foam sheet |
| EP0431668B1 (en) | 1989-12-04 | 1995-02-15 | Akzo Nobel N.V. | Recombinant herpesvirus of turkeys and live vector vaccines derived thereof |
| FR2728795B1 (fr) * | 1994-12-30 | 1997-03-21 | Rhone Merieux | Vaccin vivant recombinant aviaire, utilisant comme vecteur un virus herpes aviaire |
| US6632664B1 (en) | 1997-10-03 | 2003-10-14 | Nippon Zeon Co., Ltd. | Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same |
| US6764684B2 (en) | 2001-09-28 | 2004-07-20 | Zeon Corporation | Avian herpesvirus-based recombinant infectious bursal disease vaccine |
| WO2009156367A1 (en) | 2008-06-23 | 2009-12-30 | Intervet International B.V. | Recombinant herpesvirus of turkeys encoding for interleukin-12 |
| CN103890183A (zh) | 2011-10-21 | 2014-06-25 | 英特维特国际股份有限公司 | 编码传染性喉气管炎病毒和新城疫病毒抗原的重组非致病性马立克氏病病毒构建体 |
| BR112014008161A2 (pt) * | 2011-10-21 | 2017-04-11 | Intervet Int Bv | vírus da doença de marek não patogênico recombinante, método para a preparação do mesmo, molécula do ácido nucleico, célula hospedeira, vacina para aves domésticas, método para a preparação de uma vacina, uso de um vírus da doença de marek não patogênico recombinante, e, método de vacinação de aves domésticas |
| ME03433B (me) * | 2011-11-30 | 2020-01-20 | Merial Inc | REKOMBINANTNI VEKTORI GALLID HERPESVIRUSA 3 (MDV SEROTIP 2) KOJI EKSPRIMIRAJU ANTIGENE PTIČJIH PATHOGENA l NJIHOVE UPOTREBE |
| US9114108B2 (en) | 2011-11-30 | 2015-08-25 | Merial, Inc. | Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof |
| EP2644702A1 (en) | 2012-03-30 | 2013-10-02 | Ceva Sante Animale | Multivalent recombinant avian herpes virus and vaccine for immunizing avian species |
| RU2694318C2 (ru) | 2014-12-04 | 2019-07-11 | Интервет Интернэшнл Б.В. | Иммортализованные фибробласты эмбриона цыпленка |
-
2015
- 2015-12-22 AR ARP150104255A patent/AR103245A1/es unknown
- 2015-12-23 BR BR112017013595A patent/BR112017013595A2/pt active Search and Examination
- 2015-12-23 CN CN201580070228.0A patent/CN107002097B/zh active Active
- 2015-12-23 MX MX2017008504A patent/MX2017008504A/es active IP Right Grant
- 2015-12-23 ES ES15817860.8T patent/ES2648672T3/es active Active
- 2015-12-23 JP JP2017533847A patent/JP6246985B1/ja active Active
- 2015-12-23 EP EP15817860.8A patent/EP3185899B1/en active Active
- 2015-12-23 RU RU2017126030A patent/RU2692013C2/ru active
- 2015-12-23 PL PL15817860T patent/PL3185899T3/pl unknown
- 2015-12-23 US US15/110,628 patent/US10308956B2/en active Active
- 2015-12-23 WO PCT/EP2015/081121 patent/WO2016102647A1/en active Application Filing
- 2015-12-23 HU HUE15817860A patent/HUE035364T2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN107002097A (zh) | 2017-08-01 |
| RU2017126030A (ru) | 2019-01-24 |
| CN107002097B (zh) | 2021-06-15 |
| US10308956B2 (en) | 2019-06-04 |
| HUE035364T2 (en) | 2018-05-02 |
| AR103245A1 (es) | 2017-04-26 |
| PL3185899T3 (pl) | 2018-01-31 |
| WO2016102647A1 (en) | 2016-06-30 |
| US20170306353A1 (en) | 2017-10-26 |
| ES2648672T3 (es) | 2018-01-05 |
| BR112017013595A2 (pt) | 2018-03-06 |
| RU2692013C2 (ru) | 2019-06-19 |
| JP2018501792A (ja) | 2018-01-25 |
| JP6246985B1 (ja) | 2017-12-13 |
| EP3185899A1 (en) | 2017-07-05 |
| EP3185899B1 (en) | 2017-10-18 |
| MX2017008504A (es) | 2017-10-11 |