RU2017124487A3 - - Google Patents

Info

Publication number
RU2017124487A3
RU2017124487A3 RU2017124487A RU2017124487A RU2017124487A3 RU 2017124487 A3 RU2017124487 A3 RU 2017124487A3 RU 2017124487 A RU2017124487 A RU 2017124487A RU 2017124487 A RU2017124487 A RU 2017124487A RU 2017124487 A3 RU2017124487 A3 RU 2017124487A3
Authority
RU
Russia
Application number
RU2017124487A
Other versions
RU2017124487A (ru
RU2704826C2 (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2017124487A publication Critical patent/RU2017124487A/ru
Publication of RU2017124487A3 publication Critical patent/RU2017124487A3/ru
Application granted granted Critical
Publication of RU2704826C2 publication Critical patent/RU2704826C2/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/005Enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2017124487A 2014-12-24 2015-12-22 НОВЫЙ ПЕПТИД-ИНГИБИТОР PI3Kγ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ ОРГАНОВ ДЫХАНИЯ RU2704826C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITTO20141105 2014-12-24
ITTO2014A001105 2014-12-24
PCT/IB2015/059880 WO2016103176A1 (en) 2014-12-24 2015-12-22 Novel pi3k gamma inhibitor peptide for treatment of respiratory system diseases

Publications (3)

Publication Number Publication Date
RU2017124487A RU2017124487A (ru) 2019-01-25
RU2017124487A3 true RU2017124487A3 (ru) 2019-02-28
RU2704826C2 RU2704826C2 (ru) 2019-10-31

Family

ID=52577903

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017124487A RU2704826C2 (ru) 2014-12-24 2015-12-22 НОВЫЙ ПЕПТИД-ИНГИБИТОР PI3Kγ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ ОРГАНОВ ДЫХАНИЯ

Country Status (14)

Country Link
US (3) US10421794B2 (ru)
EP (1) EP3236983B1 (ru)
CN (2) CN113563451A (ru)
AU (1) AU2015370463B2 (ru)
BR (1) BR112017013453B1 (ru)
CA (1) CA2971121A1 (ru)
DK (1) DK3236983T3 (ru)
ES (1) ES2737227T3 (ru)
HU (1) HUE045409T2 (ru)
IL (1) IL253011B (ru)
PL (1) PL3236983T3 (ru)
PT (1) PT3236983T (ru)
RU (1) RU2704826C2 (ru)
WO (1) WO2016103176A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5409010B2 (ja) 2005-12-28 2014-02-05 バーテックス ファーマシューティカルズ インコーポレイテッド N−[2,4−ビス(1,1−ジメチルエチル)−5−ヒドロキシフェニル]−1,4−ジヒドロ−4−オキソキノリン−3−カルボキサミドの固体形態
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
KR20130056244A (ko) 2010-04-22 2013-05-29 버텍스 파마슈티칼스 인코포레이티드 시클로알킬카르복스아미도-인돌 화합물의 제조 방법
PL3925607T3 (pl) 2014-04-15 2023-10-30 Vertex Pharmaceuticals Incorporated Kompozycje farmaceutyczne do leczenia chorób, w których pośredniczy mukowiscydozowy przezbłonowy regulator przewodnictwa
RU2704826C2 (ru) 2014-12-24 2019-10-31 Китер Бьотек С.Р.Л. НОВЫЙ ПЕПТИД-ИНГИБИТОР PI3Kγ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ ОРГАНОВ ДЫХАНИЯ
IT202000012259A1 (it) * 2020-05-25 2021-11-25 Kither Biotech S R L Nuova terapia per il trattamento di malattie vascolari fibroproliferative

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1157274A1 (en) * 1999-03-02 2001-11-28 The University of Dundee Methods of determining altered ndpk functions
CA2400254A1 (en) * 2002-09-19 2004-03-19 University Health Network Compositions and methods for treating heart disease
US8236523B2 (en) 2004-08-23 2012-08-07 The Johns Hopkins University Camp reporters and high throughput assays
EP1885356A2 (en) 2005-02-17 2008-02-13 Icos Corporation Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
DE102005008921A1 (de) 2005-02-24 2006-08-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von Atemwegserkrankungen
CN101448505A (zh) * 2006-04-04 2009-06-03 加利福尼亚大学董事会 Pi3激酶拮抗剂
CA2663545A1 (en) * 2006-09-19 2008-03-27 Phylogica Limited Neuroprotective peptide inhibitors of ap-1 signaling and uses thereof
RU2010137337A (ru) * 2008-02-08 2012-03-20 Таргеджен, Инк. (US) Способы и композиции для лечения респираторных заболеваний
US20110230476A1 (en) 2009-09-09 2011-09-22 Avila Therapeutics, Inc. Pi3 kinase inhibitors and uses thereof
CA2884580A1 (en) * 2011-09-14 2013-03-21 Abeterno Limited Intracellular cell selection
RU2704826C2 (ru) 2014-12-24 2019-10-31 Китер Бьотек С.Р.Л. НОВЫЙ ПЕПТИД-ИНГИБИТОР PI3Kγ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ ОРГАНОВ ДЫХАНИЯ

Also Published As

Publication number Publication date
RU2017124487A (ru) 2019-01-25
IL253011A0 (en) 2017-08-31
CN107406488B (zh) 2021-08-31
CN107406488A (zh) 2017-11-28
DK3236983T3 (da) 2019-07-15
EP3236983B1 (en) 2019-04-17
IL253011B (en) 2021-02-28
BR112017013453A2 (pt) 2018-03-06
US10421794B2 (en) 2019-09-24
AU2015370463B2 (en) 2020-12-24
RU2704826C2 (ru) 2019-10-31
CA2971121A1 (en) 2016-06-30
ES2737227T3 (es) 2020-01-10
US10730921B2 (en) 2020-08-04
AU2015370463A1 (en) 2017-07-13
EP3236983A1 (en) 2017-11-01
US20190367571A1 (en) 2019-12-05
WO2016103176A1 (en) 2016-06-30
PL3236983T3 (pl) 2019-10-31
US11352400B2 (en) 2022-06-07
US20200317740A1 (en) 2020-10-08
BR112017013453B1 (pt) 2024-02-27
CN113563451A (zh) 2021-10-29
PT3236983T (pt) 2019-07-23
HUE045409T2 (hu) 2019-12-30
US20180086798A1 (en) 2018-03-29

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