RU2017107088A - КОМПОЗИЦИЯ НА ОСНОВЕ ANTHOSTEMA SENEGALENSE ДЛЯ ПРИМЕНЕНИЯ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА ПРОТИВ СПИДа - Google Patents
КОМПОЗИЦИЯ НА ОСНОВЕ ANTHOSTEMA SENEGALENSE ДЛЯ ПРИМЕНЕНИЯ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА ПРОТИВ СПИДа Download PDFInfo
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- RU2017107088A RU2017107088A RU2017107088A RU2017107088A RU2017107088A RU 2017107088 A RU2017107088 A RU 2017107088A RU 2017107088 A RU2017107088 A RU 2017107088A RU 2017107088 A RU2017107088 A RU 2017107088A RU 2017107088 A RU2017107088 A RU 2017107088A
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- anthostema senegalense
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- anthostema
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- 241001553164 Anthostema senegalense Species 0.000 title claims 23
- 208000030507 AIDS Diseases 0.000 title claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 15
- 239000000419 plant extract Substances 0.000 claims 5
- 241000725303 Human immunodeficiency virus Species 0.000 claims 3
- 239000001913 cellulose Substances 0.000 claims 3
- 229920002678 cellulose Polymers 0.000 claims 3
- 235000010980 cellulose Nutrition 0.000 claims 3
- 239000000284 extract Substances 0.000 claims 3
- 239000004005 microsphere Substances 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims 2
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 claims 2
- 229960002555 zidovudine Drugs 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- 229920000881 Modified starch Polymers 0.000 claims 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 229930003451 Vitamin B1 Natural products 0.000 claims 1
- 229930003471 Vitamin B2 Natural products 0.000 claims 1
- 230000001476 alcoholic effect Effects 0.000 claims 1
- 239000012675 alcoholic extract Substances 0.000 claims 1
- 230000000798 anti-retroviral effect Effects 0.000 claims 1
- 230000000840 anti-viral effect Effects 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 150000001860 citric acid derivatives Chemical class 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 claims 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 1
- 239000007919 dispersible tablet Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- -1 glidants Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 235000008216 herbs Nutrition 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 235000010755 mineral Nutrition 0.000 claims 1
- 235000019426 modified starch Nutrition 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims 1
- 229960002477 riboflavin Drugs 0.000 claims 1
- 239000011669 selenium Substances 0.000 claims 1
- 229910052711 selenium Inorganic materials 0.000 claims 1
- 235000011649 selenium Nutrition 0.000 claims 1
- 229940091258 selenium supplement Drugs 0.000 claims 1
- 239000007901 soft capsule Substances 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 235000010356 sorbitol Nutrition 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 229960003495 thiamine Drugs 0.000 claims 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims 1
- 229940098465 tincture Drugs 0.000 claims 1
- 239000011573 trace mineral Substances 0.000 claims 1
- 235000013619 trace mineral Nutrition 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 235000010374 vitamin B1 Nutrition 0.000 claims 1
- 239000011691 vitamin B1 Substances 0.000 claims 1
- 235000019164 vitamin B2 Nutrition 0.000 claims 1
- 239000011716 vitamin B2 Substances 0.000 claims 1
- 235000019160 vitamin B3 Nutrition 0.000 claims 1
- 239000011708 vitamin B3 Substances 0.000 claims 1
- 235000019158 vitamin B6 Nutrition 0.000 claims 1
- 239000011726 vitamin B6 Substances 0.000 claims 1
- 229940011671 vitamin b6 Drugs 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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Claims (15)
1. Фармацевтическая композиция на основе Anthostema senegalense для применения в качестве лекарственного средства при лечении инфекции, вызванной вирусом иммунодефицита человека (ВИЧ), СПИДа и сопутствующих клинических проявлений.
2. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 1 в качестве антиретровирусного лекарственного средства для вируса ВИЧ типа 1 или типа 2.
3. Фармацевтическая композиция на основе Anthostema senegalense для применения по любому из предшествующих пунктов, отличающаяся тем, что она получена из коры стебля Anthostema senegalense.
4. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 3, отличающаяся тем, что она получена из высушенной коры стебля.
5. Фармацевтическая композиция на основе Anthostema senegalense для применения по любому из предшествующих пунктов, отличающаяся тем, что она содержит растительный экстракт Anthostema senegalense.
6. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 5, отличающаяся тем, что растительный экстракт Anthostema senegalense представляет собой полярный, водный, спиртовой или водно-спиртовой экстракт.
7. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 6, отличающаяся тем, что растительный экстракт Anthostema senegalense представляет собой матричную настойку Anthostema senegalense с содержанием этанола примерно 70 об. %.
8. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 5, отличающаяся тем, что растительный экстракт Anthostema senegalense представляет собой неполярным экстракт.
9. Фармацевтическая композиция на основе Anthostema senegalense для применения по любому из предшествующих пунктов, отличающаяся тем, что она дополнительно содержит одно или несколько соединений или вспомогательных веществ, выбранных из экстрактов из растительных экстрактов, витаминов, минералов, микроэлементов, ароматических веществ, монтажных агентов, связующих соединений, скользящих соединений, смазывающих соединений, поверхностно-активных веществ, сахаров, лактозы, сорбитола, маннитола, крахмалов и модифицированных крахмалов, мальтодекстринов, карбонатов, цитратов, желатина, поливинилпирролидона, полисахаридов, производных целлюлозы, сшитой натрий-карбоксиметилцеллюлозы, микрокристаллической целлюлозы, мелкодисперсной целлюлозы, слабозамещенных гидроксипропилированных целлюлозных полимеров, а также антивирусных или антиретровирусных веществ.
10. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 9, отличающаяся тем, что она дополнительно содержит зидовудин, азидотимидин, витамин РР, витамин В1, витамин В2, витамин В6 или селен.
11. Фармацевтическая композиция на основе Anthostema senegalense для применения по любому из предшествующих пунктов, отличающаяся тем, что она представлена в виде пероральной галеновой формы.
12. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 11, отличающаяся тем, что она представлена в галеновой форме в виде пакетиков с травами, микросфер, таблеток, диспергируемых в ротовой полости таблеток, мягких капсул, гранул, капсул, порошка, ампул, сиропа, отвара или жидкого экстракта.
13. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 12, отличающаяся тем, что она представлена в галеновой форме в виде пакетиков с травами, содержащих около пяти граммов крупномолотой коры стебля Anthostema senegalense.
14. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 12, отличающаяся тем, что она представлена в галеновой форме в виде микросфер, полученных методом экструзии и сфероидизации.
15. Фармацевтическая композиция на основе Anthostema senegalense для применения по п. 14, отличающаяся тем, что микросферы сгруппированы в капсулы.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1455226A FR3021871B1 (fr) | 2014-06-10 | 2014-06-10 | Composition a base d'anthostema senegalense utilisee comme medicament contre le sida |
| FR1455226 | 2014-06-10 | ||
| PCT/FR2015/050413 WO2015189487A1 (fr) | 2014-06-10 | 2015-02-20 | Composition à base d'anthostema senegalense utilisée comme médicament contre le sida |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2017107088A true RU2017107088A (ru) | 2018-09-05 |
| RU2017107088A3 RU2017107088A3 (ru) | 2018-09-05 |
| RU2674247C2 RU2674247C2 (ru) | 2018-12-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| RU2017107088A RU2674247C2 (ru) | 2014-06-10 | 2015-02-20 | КОМПОЗИЦИЯ НА ОСНОВЕ ANTHOSTEMA SENEGALENSE ДЛЯ ПРИМЕНЕНИЯ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА ПРОТИВ СПИДа |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10517826B2 (ru) |
| EP (1) | EP3209284B1 (ru) |
| CN (1) | CN106572975B (ru) |
| AP (1) | AP2017009784A0 (ru) |
| FR (1) | FR3021871B1 (ru) |
| RU (1) | RU2674247C2 (ru) |
| WO (1) | WO2015189487A1 (ru) |
| ZA (1) | ZA201701714B (ru) |
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| FR3057865A1 (fr) * | 2016-10-21 | 2018-04-27 | Laboratoire Michel Iderne | Composition chimique |
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| US3764697A (en) * | 1972-04-19 | 1973-10-09 | American Cyanamid Co | Method of using di-, tri- and tetrachlorobenzonitriles for controlling helminths |
| US5178865A (en) * | 1990-06-19 | 1993-01-12 | Cedars-Sinai Medical Center | Chinese herbal extracts in the treatment of hiv related disease in vitro |
| US20040052868A1 (en) * | 2002-09-12 | 2004-03-18 | William Asiedu | Composition treating for AIDS and associated conditions |
| FR2859107B1 (fr) * | 2003-08-26 | 2008-04-18 | Oyoubi Pierre Pyebi | Utilisation des extraits d'une graminee, d'une rutacee et d'une pieridophyte dans une composition pharmaceutique a activite antivirale, antibacterienne, antifongique et aussi destinee a stimuler les defenses immunitaires |
| AP2008004567A0 (en) * | 2006-01-31 | 2008-08-31 | Parsroos Co | Use of a combination of ethanolic Rosa SP., UrticaDiaca and tanacetum vulgare extracts, further com prising selenium and aure and having been exposed to a pulsed electromagnetic field, for the preparation of a medicament for immunostimulation and/or tratment of HIV infections |
| CN101215327A (zh) * | 2007-01-04 | 2008-07-09 | 中国科学院福建物质结构研究所 | 南瓜蛋白及其编码基因 |
| WO2011014561A1 (en) * | 2009-07-29 | 2011-02-03 | He Johnny J | Extracts of medicinal plant and uses thereof |
| FR2952824B1 (fr) * | 2009-11-23 | 2011-11-11 | Aliou Mamadou Balde | Composition antidiabetique contenant un extrait vegetal d'englerina lecardii |
| CN101898940A (zh) * | 2010-03-03 | 2010-12-01 | 饶力群 | 一种从叶下珠中分离纯化叶下珠素的方法 |
| CN102716177B (zh) * | 2012-07-10 | 2014-02-19 | 南京中医药大学 | 鲜泽漆汁在制备抗单纯疱疹病毒药物中的应用 |
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2014
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| FR3021871B1 (fr) | 2018-07-13 |
| RU2017107088A3 (ru) | 2018-09-05 |
| US10517826B2 (en) | 2019-12-31 |
| AP2017009784A0 (en) | 2017-02-28 |
| RU2674247C2 (ru) | 2018-12-07 |
| EP3209284A1 (fr) | 2017-08-30 |
| EP3209284B1 (fr) | 2018-11-14 |
| ZA201701714B (en) | 2018-08-29 |
| FR3021871A1 (fr) | 2015-12-11 |
| CN106572975A (zh) | 2017-04-19 |
| CN106572975B (zh) | 2019-10-25 |
| WO2015189487A1 (fr) | 2015-12-17 |
| US20170326070A1 (en) | 2017-11-16 |
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