RU2015120467A - Контроль полового созревания у животных - Google Patents
Контроль полового созревания у животных Download PDFInfo
- Publication number
- RU2015120467A RU2015120467A RU2015120467A RU2015120467A RU2015120467A RU 2015120467 A RU2015120467 A RU 2015120467A RU 2015120467 A RU2015120467 A RU 2015120467A RU 2015120467 A RU2015120467 A RU 2015120467A RU 2015120467 A RU2015120467 A RU 2015120467A
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- Prior art keywords
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Links
- 241001465754 Metazoa Species 0.000 title claims abstract 29
- 238000000034 method Methods 0.000 claims abstract 37
- 108090000623 proteins and genes Proteins 0.000 claims abstract 33
- 230000000955 neuroendocrine Effects 0.000 claims abstract 14
- 239000003795 chemical substances by application Substances 0.000 claims abstract 13
- 102000018120 Recombinases Human genes 0.000 claims abstract 12
- 108010091086 Recombinases Proteins 0.000 claims abstract 12
- 230000002779 inactivation Effects 0.000 claims abstract 10
- 210000004027 cell Anatomy 0.000 claims abstract 9
- 108020001507 fusion proteins Proteins 0.000 claims abstract 9
- 102000037865 fusion proteins Human genes 0.000 claims abstract 9
- 150000007523 nucleic acids Chemical group 0.000 claims abstract 9
- 101150075823 KISS1 gene Proteins 0.000 claims abstract 7
- 101150020170 KISS1R gene Proteins 0.000 claims abstract 7
- 238000010459 TALEN Methods 0.000 claims abstract 7
- 108010043645 Transcription Activator-Like Effector Nucleases Proteins 0.000 claims abstract 7
- 108091033409 CRISPR Proteins 0.000 claims abstract 6
- 108091028043 Nucleic acid sequence Proteins 0.000 claims abstract 6
- 210000001161 mammalian embryo Anatomy 0.000 claims abstract 5
- 210000000349 chromosome Anatomy 0.000 claims abstract 4
- 238000010354 CRISPR gene editing Methods 0.000 claims abstract 3
- 108700019146 Transgenes Proteins 0.000 claims abstract 3
- 108010017070 Zinc Finger Nucleases Proteins 0.000 claims abstract 3
- 210000004102 animal cell Anatomy 0.000 claims abstract 3
- 239000011159 matrix material Substances 0.000 claims abstract 3
- 108020004707 nucleic acids Proteins 0.000 claims abstract 3
- 102000039446 nucleic acids Human genes 0.000 claims abstract 3
- 230000009870 specific binding Effects 0.000 claims abstract 3
- 108020004414 DNA Proteins 0.000 claims abstract 2
- 230000002759 chromosomal effect Effects 0.000 claims abstract 2
- 108091023040 Transcription factor Proteins 0.000 claims 6
- 241000251468 Actinopterygii Species 0.000 claims 3
- 241000283690 Bos taurus Species 0.000 claims 3
- 241000283707 Capra Species 0.000 claims 3
- 241000287828 Gallus gallus Species 0.000 claims 3
- 241001494479 Pecora Species 0.000 claims 3
- 241000282898 Sus scrofa Species 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 108091062157 Cis-regulatory element Proteins 0.000 claims 2
- 102000006771 Gonadotropins Human genes 0.000 claims 2
- 108010086677 Gonadotropins Proteins 0.000 claims 2
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 2
- 210000002459 blastocyst Anatomy 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 210000004602 germ cell Anatomy 0.000 claims 2
- 239000002622 gonadotropin Substances 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 230000002452 interceptive effect Effects 0.000 claims 2
- 230000005070 ripening Effects 0.000 claims 2
- 210000001082 somatic cell Anatomy 0.000 claims 2
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 1
- 238000010367 cloning Methods 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8778—Swine embryos
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/101—Bovine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/40—Fish
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Environmental Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Developmental Biology & Embryology (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- Animal Behavior & Ethology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Cell Biology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261720187P | 2012-10-30 | 2012-10-30 | |
| US61/720,187 | 2012-10-30 | ||
| US201361870510P | 2013-08-27 | 2013-08-27 | |
| US61/870,510 | 2013-08-27 | ||
| PCT/US2013/067502 WO2014070887A1 (en) | 2012-10-30 | 2013-10-30 | Control of sexual maturation in animals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2015120467A true RU2015120467A (ru) | 2016-12-20 |
Family
ID=50548813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015120467A RU2015120467A (ru) | 2012-10-30 | 2013-10-30 | Контроль полового созревания у животных |
Country Status (15)
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US10920242B2 (en) | 2011-02-25 | 2021-02-16 | Recombinetics, Inc. | Non-meiotic allele introgression |
| CA2853829C (en) | 2011-07-22 | 2023-09-26 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| GB201122458D0 (en) | 2011-12-30 | 2012-02-08 | Univ Wageningen | Modified cascade ribonucleoproteins and uses thereof |
| GB2537000C (en) | 2012-05-25 | 2019-10-09 | Univ California | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| CA2891347C (en) | 2012-12-06 | 2018-02-27 | Sigma-Aldrich Co. Llc | Crispr-based genome modification and regulation |
| AU2014235794A1 (en) | 2013-03-14 | 2015-10-22 | Caribou Biosciences, Inc. | Compositions and methods of nucleic acid-targeting nucleic acids |
| US20140359796A1 (en) * | 2013-05-31 | 2014-12-04 | Recombinetics, Inc. | Genetically sterile animals |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| AU2014337790B2 (en) | 2013-10-25 | 2019-09-26 | Livestock Improvement Corporation Limited | Genetic markers and uses therefor |
| CN111218447B (zh) | 2013-11-07 | 2024-10-11 | 爱迪塔斯医药有限公司 | 使用统治型gRNA的CRISPR相关方法和组合物 |
| US20150166982A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting pi3k point mutations |
| AU2015253352A1 (en) | 2014-04-28 | 2016-12-08 | Recombinetics, Inc. | Multiplex Gene Editing |
| EP3177718B1 (en) | 2014-07-30 | 2022-03-16 | President and Fellows of Harvard College | Cas9 proteins including ligand-dependent inteins |
| MX2017007712A (es) * | 2014-12-18 | 2017-10-27 | Pioneer Hi Bred Int | Metodos moleculares mejorados de reproduccion. |
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| JP6837223B2 (ja) * | 2015-03-17 | 2021-03-03 | 国立研究開発法人水産研究・教育機構 | 生物個体群の縮小方法 |
| SG11201803173VA (en) | 2015-10-23 | 2018-05-30 | Harvard College | Nucleobase editors and uses thereof |
| EP3472329A1 (en) * | 2016-06-16 | 2019-04-24 | Oslo Universitetssykehus HF | Improved gene editing |
| JP7231935B2 (ja) | 2016-08-03 | 2023-03-08 | プレジデント アンド フェローズ オブ ハーバード カレッジ | アデノシン核酸塩基編集因子およびそれらの使用 |
| CA3033327A1 (en) | 2016-08-09 | 2018-02-15 | President And Fellows Of Harvard College | Programmable cas9-recombinase fusion proteins and uses thereof |
| WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| US20180084767A1 (en) | 2016-09-21 | 2018-03-29 | Recombinetics, Inc. | Animal models for cardiomyopathy |
| WO2018071868A1 (en) | 2016-10-14 | 2018-04-19 | President And Fellows Of Harvard College | Aav delivery of nucleobase editors |
| GB201617559D0 (en) | 2016-10-17 | 2016-11-30 | University Court Of The University Of Edinburgh The | Swine comprising modified cd163 and associated methods |
| US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
| US12390514B2 (en) | 2017-03-09 | 2025-08-19 | President And Fellows Of Harvard College | Cancer vaccine |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| JP2020510439A (ja) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | シトシンからグアニンへの塩基編集因子 |
| KR20240116572A (ko) | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
| US11560566B2 (en) | 2017-05-12 | 2023-01-24 | President And Fellows Of Harvard College | Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation |
| EP3658573A1 (en) | 2017-07-28 | 2020-06-03 | President and Fellows of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace) |
| WO2019139645A2 (en) | 2017-08-30 | 2019-07-18 | President And Fellows Of Harvard College | High efficiency base editors comprising gam |
| AU2018352592C1 (en) | 2017-10-16 | 2025-09-25 | Beam Therapeutics, Inc. | Uses of adenosine base editors |
| CN107760722B (zh) * | 2017-12-07 | 2020-11-06 | 中国科学院水生生物研究所 | 一种鲟鱼显微注射的方法及应用 |
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| JP2020146301A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
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| JP2020146312A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146302A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146298A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146310A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146318A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146314A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
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| JP2020146308A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
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| JP2020146297A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146307A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146316A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146317A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146309A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146313A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
| JP2020146303A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
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| CN110452995B (zh) * | 2019-08-27 | 2021-06-15 | 浙江大学 | 影响嘉兴黑猪母猪繁殖性能的gpr54基因分子标记及其应用 |
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| CN111616830A (zh) * | 2020-07-03 | 2020-09-04 | 宁夏大学 | 一种新型icr小鼠超数排卵方法 |
| CN113025723B (zh) * | 2021-01-08 | 2023-01-20 | 华中农业大学 | 一种提高绵羊产羔数的snp标记、检测方法及其应用 |
| CN112790125B (zh) * | 2021-01-22 | 2022-09-06 | 中国科学院水生生物研究所 | 一种玉兔百褶裙泰狮金鱼的创制方法 |
| GB202118058D0 (en) | 2021-12-14 | 2022-01-26 | Univ Warwick | Methods to increase yields in crops |
| GB2621813A (en) | 2022-06-30 | 2024-02-28 | Univ Newcastle | Preventing disease recurrence in Mitochondrial replacement therapy |
| IL320374A (en) * | 2022-10-24 | 2025-06-01 | Univ California | Methods for sexual classification of insects |
| GB202314578D0 (en) | 2023-09-22 | 2023-11-08 | Univ Manchester | Methods of producing homoplasmic modified plants or parts thereof |
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| CA2081660C (en) * | 1991-03-01 | 2001-05-01 | Raymond Dufour | Method for improving the organoleptic qualities of the meat from uncastrated male domestic animals and vaccine set for use in this method |
| AU2003262379A1 (en) * | 2002-04-16 | 2003-11-03 | Auburn University | TRANSIENT AND/OR PERMANENT MODIFICATION OF SEXUAL BEHAVIOR AND/OR FERTILITY USING RECOMBINANT CHIMERIC GnRH |
| AU2003301569A1 (en) * | 2002-10-25 | 2004-05-13 | Paradigm Therapeutics Limited | Gpr54 knock-out mammals and screening methods using them |
| JP2013500018A (ja) * | 2009-07-24 | 2013-01-07 | シグマ−アルドリッチ・カンパニー・リミテッド・ライアビリティ・カンパニー | ゲノム編集のための方法 |
| EP2462230B1 (en) * | 2009-08-03 | 2015-07-15 | Recombinetics, Inc. | Methods and compositions for targeted gene modification |
| CA2770312A1 (en) * | 2009-08-11 | 2011-02-17 | Sangamo Biosciences, Inc. | Organisms homozygous for targeted modification |
| WO2011072246A2 (en) * | 2009-12-10 | 2011-06-16 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
| WO2012116274A2 (en) * | 2011-02-25 | 2012-08-30 | Recombinetics, Inc. | Genetically modified animals and methods for making the same |
| US9770011B2 (en) * | 2012-09-29 | 2017-09-26 | The Trustees Of The University Of Pennsylvania | Veterinary composition and methods for non-surgical neutering and castration |
-
2013
- 2013-10-30 KR KR1020157014564A patent/KR20150100651A/ko not_active Ceased
- 2013-10-30 US US14/067,634 patent/US20140123330A1/en not_active Abandoned
- 2013-10-30 WO PCT/US2013/067502 patent/WO2014070887A1/en not_active Ceased
- 2013-10-30 EP EP13851242.1A patent/EP2914714A4/en not_active Withdrawn
- 2013-10-30 CA CA2889502A patent/CA2889502A1/en not_active Abandoned
- 2013-10-30 AU AU2013337951A patent/AU2013337951B2/en not_active Ceased
- 2013-10-30 MX MX2015005255A patent/MX2015005255A/es unknown
- 2013-10-30 CN CN201380067471.8A patent/CN105073981A/zh active Pending
- 2013-10-30 BR BR112015009589A patent/BR112015009589A2/pt not_active IP Right Cessation
- 2013-10-30 JP JP2015539942A patent/JP2015533284A/ja active Pending
- 2013-10-30 NZ NZ629578A patent/NZ629578A/en not_active IP Right Cessation
- 2013-10-30 AR ARP130103958A patent/AR093291A1/es unknown
- 2013-10-30 AP AP2015008495A patent/AP2015008495A0/xx unknown
- 2013-10-30 RU RU2015120467A patent/RU2015120467A/ru not_active Application Discontinuation
-
2015
- 2015-04-29 PH PH12015500957A patent/PH12015500957A1/en unknown
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2018
- 2018-10-25 JP JP2018200938A patent/JP2019047794A/ja active Pending
Also Published As
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|---|---|
| CA2889502A1 (en) | 2014-05-08 |
| BR112015009589A2 (pt) | 2017-11-14 |
| AU2013337951B2 (en) | 2019-10-03 |
| EP2914714A1 (en) | 2015-09-09 |
| MX2015005255A (es) | 2015-10-29 |
| AR093291A1 (es) | 2015-05-27 |
| PH12015500957A1 (en) | 2015-08-10 |
| JP2015533284A (ja) | 2015-11-24 |
| WO2014070887A1 (en) | 2014-05-08 |
| AU2013337951A1 (en) | 2015-06-11 |
| EP2914714A4 (en) | 2016-09-21 |
| CN105073981A (zh) | 2015-11-18 |
| KR20150100651A (ko) | 2015-09-02 |
| NZ629578A (en) | 2017-06-30 |
| US20140123330A1 (en) | 2014-05-01 |
| AP2015008495A0 (en) | 2015-05-31 |
| JP2019047794A (ja) | 2019-03-28 |
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| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20161031 |