RU2014118985A - METHOD FOR PRODUCING ROSE FLAVANOID NANOCAPSULES - Google Patents

METHOD FOR PRODUCING ROSE FLAVANOID NANOCAPSULES Download PDF

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Publication number
RU2014118985A
RU2014118985A RU2014118985/15A RU2014118985A RU2014118985A RU 2014118985 A RU2014118985 A RU 2014118985A RU 2014118985/15 A RU2014118985/15 A RU 2014118985/15A RU 2014118985 A RU2014118985 A RU 2014118985A RU 2014118985 A RU2014118985 A RU 2014118985A
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RU
Russia
Prior art keywords
flavanoid
nanocapsules
rosehip
producing
producing rose
Prior art date
Application number
RU2014118985/15A
Other languages
Russian (ru)
Other versions
RU2578404C2 (en
Inventor
Александр Александрович Кролевец
Галина Николаевна Дубцова
Илья Александрович Богачев
Ирина Александровна Дедова
Original Assignee
Александр Александрович Кролевец
Галина Николаевна Дубцова
Илья Александрович Богачев
Ирина Александровна Дедова
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Александр Александрович Кролевец, Галина Николаевна Дубцова, Илья Александрович Богачев, Ирина Александровна Дедова filed Critical Александр Александрович Кролевец
Priority to RU2014118985/15A priority Critical patent/RU2578404C2/en
Publication of RU2014118985A publication Critical patent/RU2014118985A/en
Application granted granted Critical
Publication of RU2578404C2 publication Critical patent/RU2578404C2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • B82B3/0009—Forming specific nanostructures

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Inorganic Chemistry (AREA)
  • Microbiology (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Способ получения нанокапсул флаваноидов шиповника, характеризующийся тем, что в качестве оболочки микрокапсул используется альгинат натрия, а в качестве ядра - флаваноиды шиповника при их получении физико-химическим методом осаждения нерастворителем с использованием хлороформа в качестве осадителя.A method for producing rosehip flavanoid nanocapsules, characterized in that sodium alginate is used as the shell of the microcapsules, and rosehip flavanoids are used as the core by the physicochemical method of precipitation with a non-solvent using chloroform as a precipitant.

Claims (1)

Способ получения нанокапсул флаваноидов шиповника, характеризующийся тем, что в качестве оболочки микрокапсул используется альгинат натрия, а в качестве ядра - флаваноиды шиповника при их получении физико-химическим методом осаждения нерастворителем с использованием хлороформа в качестве осадителя. A method for producing rosehip flavanoid nanocapsules, characterized in that sodium alginate is used as a microcapsule shell, and rosehip flavanoids are used as a core by physicochemical precipitation with a non-solvent using chloroform as a precipitant.
RU2014118985/15A 2014-05-12 2014-05-12 Method of producing nanocapsules of rosehip flavonoids RU2578404C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2014118985/15A RU2578404C2 (en) 2014-05-12 2014-05-12 Method of producing nanocapsules of rosehip flavonoids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2014118985/15A RU2578404C2 (en) 2014-05-12 2014-05-12 Method of producing nanocapsules of rosehip flavonoids

Publications (2)

Publication Number Publication Date
RU2014118985A true RU2014118985A (en) 2015-11-20
RU2578404C2 RU2578404C2 (en) 2016-03-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014118985/15A RU2578404C2 (en) 2014-05-12 2014-05-12 Method of producing nanocapsules of rosehip flavonoids

Country Status (1)

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RU (1) RU2578404C2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2674652C1 (en) * 2018-01-10 2018-12-12 Александр Александрович Кролевец Method of producing nanocapules of dry elecampane extract

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2134967C1 (en) * 1997-05-30 1999-08-27 Шестаков Константин Алексеевич Method of preparing microcapsulated preparations containing pyrethroid insecticides
RU2496483C1 (en) * 2012-03-20 2013-10-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Юго-Западный государственный университет" (ЮЗ ГУ) Method for preparing microcapsules
CN103315977B (en) * 2013-06-28 2015-07-08 山东大学 Folic acid modified quercetin lipid nano-capsule preparation and preparation method thereof

Also Published As

Publication number Publication date
RU2578404C2 (en) 2016-03-27

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