RU2012108110A - Применение меланокортинов для лечения дислипидемии - Google Patents
Применение меланокортинов для лечения дислипидемии Download PDFInfo
- Publication number
- RU2012108110A RU2012108110A RU2012108110/15A RU2012108110A RU2012108110A RU 2012108110 A RU2012108110 A RU 2012108110A RU 2012108110/15 A RU2012108110/15 A RU 2012108110/15A RU 2012108110 A RU2012108110 A RU 2012108110A RU 2012108110 A RU2012108110 A RU 2012108110A
- Authority
- RU
- Russia
- Prior art keywords
- arg
- cys
- ala
- trp
- phe
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- A61K38/34—Melanocyte stimulating hormone [MSH], e.g. alpha- or beta-melanotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27348809P | 2009-08-05 | 2009-08-05 | |
| US61/273,488 | 2009-08-05 | ||
| PCT/US2010/043832 WO2011017209A1 (en) | 2009-08-05 | 2010-07-30 | Use of melanocortins to treat dyslipidemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012108110A true RU2012108110A (ru) | 2013-09-10 |
Family
ID=43544604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012108110/15A RU2012108110A (ru) | 2009-08-05 | 2010-07-30 | Применение меланокортинов для лечения дислипидемии |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20120135923A1 (enExample) |
| EP (1) | EP2461681A4 (enExample) |
| JP (1) | JP2013501053A (enExample) |
| KR (1) | KR20120059520A (enExample) |
| CN (1) | CN102548399A (enExample) |
| AU (1) | AU2010279719A1 (enExample) |
| BR (1) | BR112012002445A2 (enExample) |
| CA (1) | CA2769883A1 (enExample) |
| IN (1) | IN2012DN01493A (enExample) |
| MX (1) | MX2012001513A (enExample) |
| RU (1) | RU2012108110A (enExample) |
| WO (1) | WO2011017209A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR201815292T4 (tr) | 2007-11-05 | 2018-11-21 | Board Of Supervisors Of Louisiana State Univ And Agriculture And Mechanical College | İnsüli̇n duyarliliğinin tedavi̇si̇nde melanokorti̇nleri̇n kullanimi. |
| JP2013510881A (ja) * | 2009-11-16 | 2013-03-28 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | Ａｃ−Ａｒｇ−シクロ（Ｃｙｓ−Ｄ−Ａｌａ−Ｈｉｓ−Ｄ−Ｐｈｅ−Ａｒｇ−Ｔｒｐ−Ｃｙｓ）−ＮＨ２の合成のための方法 |
| BR112013027222B1 (pt) * | 2011-06-14 | 2022-07-12 | Ipsen Pharma S.A.S. | Composição de liberação sustentada que contém peptídeos como ingrediente ativo |
| CA3301962A1 (en) | 2011-12-29 | 2026-03-02 | Rhythm Pharmaceuticals, Inc. | Method of treating melanocortin-4 receptor-associated disorders in heterozygous carriers |
| US10196425B2 (en) * | 2013-03-15 | 2019-02-05 | Rhythm Pharmaceuticals, Inc. | Peptide compositions |
| PT2970389T (pt) | 2013-03-15 | 2020-10-21 | Rhythm Pharmaceuticals Inc | Composições farmacêuticas |
| PT3356386T (pt) | 2015-09-30 | 2024-05-17 | Rhythm Pharmaceuticals Inc | Método de tratamento de distúrbios associados à via do receptor da melanocortina-4 |
| WO2019219714A1 (en) * | 2018-05-15 | 2019-11-21 | Novo Nordisk A/S | Compounds capable of binding to melanocortin 4 receptor |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005000217A2 (en) * | 2003-06-06 | 2005-01-06 | Merck & Co., Inc. | Combination therapy for the treatment of dyslipidemia |
| US20080306008A1 (en) * | 2004-11-04 | 2008-12-11 | Nova Nordisk A/S | Peptides for Use in the Treatment of Obesity |
| AU2006269321A1 (en) * | 2005-07-08 | 2007-01-18 | Ipsen Pharma S.A.S. | Ligands of melanocortin receptors |
| KR100997177B1 (ko) * | 2005-07-08 | 2010-11-29 | 입센 파마 에스.에이.에스 | 멜라노코르틴 수용체 리간드 |
| EP2148692B1 (en) * | 2007-05-25 | 2017-01-25 | Ipsen Pharma S.A.S. | Melanocortin receptor ligands modified with hydantoin |
| EP2167112A4 (en) * | 2007-06-15 | 2012-01-25 | Ipsen Pharma Sas | CYCLIC PEPTIDE MELANOCORTIN RECEPTOR LIGANDS |
| TR201815292T4 (tr) * | 2007-11-05 | 2018-11-21 | Board Of Supervisors Of Louisiana State Univ And Agriculture And Mechanical College | İnsüli̇n duyarliliğinin tedavi̇si̇nde melanokorti̇nleri̇n kullanimi. |
-
2010
- 2010-07-30 KR KR1020127005642A patent/KR20120059520A/ko not_active Ceased
- 2010-07-30 CA CA2769883A patent/CA2769883A1/en not_active Abandoned
- 2010-07-30 US US13/388,387 patent/US20120135923A1/en not_active Abandoned
- 2010-07-30 CN CN2010800419706A patent/CN102548399A/zh active Pending
- 2010-07-30 JP JP2012523666A patent/JP2013501053A/ja not_active Withdrawn
- 2010-07-30 AU AU2010279719A patent/AU2010279719A1/en not_active Abandoned
- 2010-07-30 WO PCT/US2010/043832 patent/WO2011017209A1/en not_active Ceased
- 2010-07-30 BR BR112012002445A patent/BR112012002445A2/pt not_active IP Right Cessation
- 2010-07-30 EP EP10806956.8A patent/EP2461681A4/en not_active Withdrawn
- 2010-07-30 IN IN1493DEN2012 patent/IN2012DN01493A/en unknown
- 2010-07-30 MX MX2012001513A patent/MX2012001513A/es not_active Application Discontinuation
- 2010-07-30 RU RU2012108110/15A patent/RU2012108110A/ru not_active Application Discontinuation
-
2013
- 2013-08-21 US US13/972,279 patent/US20130331324A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130331324A1 (en) | 2013-12-12 |
| JP2013501053A (ja) | 2013-01-10 |
| KR20120059520A (ko) | 2012-06-08 |
| EP2461681A4 (en) | 2013-04-24 |
| IN2012DN01493A (enExample) | 2015-06-05 |
| WO2011017209A1 (en) | 2011-02-10 |
| MX2012001513A (es) | 2012-05-22 |
| US20120135923A1 (en) | 2012-05-31 |
| AU2010279719A1 (en) | 2012-03-01 |
| CA2769883A1 (en) | 2011-02-10 |
| BR112012002445A2 (pt) | 2015-10-13 |
| EP2461681A1 (en) | 2012-06-13 |
| CN102548399A (zh) | 2012-07-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20131121 |