RU2011127771A - 2,6-DIISOBORNYLPHENOLS - Google Patents

2,6-DIISOBORNYLPHENOLS Download PDF

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Publication number
RU2011127771A
RU2011127771A RU2011127771/04A RU2011127771A RU2011127771A RU 2011127771 A RU2011127771 A RU 2011127771A RU 2011127771/04 A RU2011127771/04 A RU 2011127771/04A RU 2011127771 A RU2011127771 A RU 2011127771A RU 2011127771 A RU2011127771 A RU 2011127771A
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RU
Russia
Prior art keywords
isobornyl
moieties
configuration
diisobornylphenols
formula
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RU2011127771/04A
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Russian (ru)
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RU2502719C2 (en
Inventor
Александр Васильевич Кучин
Ирина Юрьевна Чукичева
Original Assignee
Учреждение Российской академии наук Институт химии Коми научного центра Уральского отделения РАН
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Application filed by Учреждение Российской академии наук Институт химии Коми научного центра Уральского отделения РАН filed Critical Учреждение Российской академии наук Институт химии Коми научного центра Уральского отделения РАН
Priority to RU2011127771/04A priority Critical patent/RU2502719C2/en
Priority to PCT/RU2012/000534 priority patent/WO2013006099A2/en
Publication of RU2011127771A publication Critical patent/RU2011127771A/en
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Publication of RU2502719C2 publication Critical patent/RU2502719C2/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Abstract

Группа соединений представлена формулой (I)где R=H, СН,где изоборнильные фрагменты имеют конфигурацию (1S, 2R, 4R, 1'R, 2'S, 4'S) или изоборнильные фрагменты имеют конфигурацию (1S, 2R, 4R, 1'S, 2'R, 4'R) и (1R, 2S, 4S 1'R, 2'S, 4'S).A group of compounds is represented by formula (I) where R = H, CH, where the isobornyl moieties have the configuration (1S, 2R, 4R, 1'R, 2'S, 4'S) or the isobornyl moieties have the configuration (1S, 2R, 4R, 1'S, 2 ' R, 4'R) and (1R, 2S, 4S 1'R, 2'S, 4'S).

Claims (1)

Группа соединений представлена формулой (I)The group of compounds represented by formula (I)
Figure 00000001
Figure 00000001
 где R1=H, СН3,where R 1 = H, CH 3 , где изоборнильные фрагменты имеют конфигурацию (1S, 2R, 4R, 1'R, 2'S, 4'S) или изоборнильные фрагменты имеют конфигурацию (1S, 2R, 4R, 1'S, 2'R, 4'R) и (1R, 2S, 4S 1'R, 2'S, 4'S). where the isobornyl moieties have the configuration (1S, 2R, 4R, 1'R, 2'S, 4'S) or the isobornyl moieties have the configuration (1S, 2R, 4R, 1'S, 2'R, 4'R) and (1R, 2S, 4S 1 'R, 2'S, 4'S).
RU2011127771/04A 2011-07-06 2011-07-06 2,6-diisobornylphenols RU2502719C2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
RU2011127771/04A RU2502719C2 (en) 2011-07-06 2011-07-06 2,6-diisobornylphenols
PCT/RU2012/000534 WO2013006099A2 (en) 2011-07-06 2012-06-27 2,6-diisobornylphenols

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2011127771/04A RU2502719C2 (en) 2011-07-06 2011-07-06 2,6-diisobornylphenols

Publications (2)

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RU2011127771A true RU2011127771A (en) 2013-01-20
RU2502719C2 RU2502719C2 (en) 2013-12-27

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RU (1) RU2502719C2 (en)
WO (1) WO2013006099A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2555335C1 (en) * 2014-02-06 2015-07-10 Общество с ограниченной ответственностью "Диборнол Девелопмент" Medication for treatment of cardiovascular diseases

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2568437C1 (en) * 2014-10-30 2015-11-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Химии Коми Научного Центра Уральского Отделения Российской Академии Наук Sulphur-containing 2,6-diisobornylphenol derivatives
RU2642062C2 (en) * 2016-06-06 2018-01-24 Федеральное Государственное Бюджетное Учреждение Науки Институт Химии Коми Научного Центра Уральского Отделения Российской Академии Наук Hybrid terpenophenols with isobornyl and 1-phenylethyl or 1-phenylpropyl substituents and their application as agent, possessing anti-radical, antioxidant and membrane-protection activity
RU2016138751A (en) * 2016-09-30 2018-04-02 Общество с ограниченной ответственностью "Диборнол Девелопмент" Cardiovascular Treatment
RU2757874C1 (en) * 2019-10-30 2021-10-22 Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) Drug with complex pharmacological effect for the treatment of cardiovascular diseases, correction of cerebral circulation disorders, treatment of consequences of cerebrovascular diseases (options)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2375342C2 (en) * 2008-01-22 2009-12-10 ОАО "Ангарский завод полимеров" (ОАО АЗП) Method of inhibiting thermopolymerisation when processing liquid pyrolysis products
RU2394807C2 (en) * 2008-05-28 2010-07-20 Институт химии Коми Научного центра Уральского отделения Российской Академии Наук Method of producing 2,6-diisobornyl-4-methylphenol

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2555335C1 (en) * 2014-02-06 2015-07-10 Общество с ограниченной ответственностью "Диборнол Девелопмент" Medication for treatment of cardiovascular diseases
RU2555335C9 (en) * 2014-02-06 2016-09-10 Общество с ограниченной ответственностью "Диборнол Девелопмент" Medication for treatment of cardiovascular diseases

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WO2013006099A2 (en) 2013-01-10
RU2502719C2 (en) 2013-12-27
WO2013006099A3 (en) 2013-04-11

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20131120

NF4A Reinstatement of patent

Effective date: 20150120