RU2016138751A - Cardiovascular Treatment - Google Patents

Cardiovascular Treatment Download PDF

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Publication number
RU2016138751A
RU2016138751A RU2016138751A RU2016138751A RU2016138751A RU 2016138751 A RU2016138751 A RU 2016138751A RU 2016138751 A RU2016138751 A RU 2016138751A RU 2016138751 A RU2016138751 A RU 2016138751A RU 2016138751 A RU2016138751 A RU 2016138751A
Authority
RU
Russia
Prior art keywords
trimethylbicyclo
hept
isomer
cardiovascular treatment
methylphenol
Prior art date
Application number
RU2016138751A
Other languages
Russian (ru)
Inventor
Кенес Тагаевич Еримбетов
Виктор Владимирович Хомиченок
Анна Яковлевна Гончарова
Рахимджан Ахметджанович Розиев
Екатерина Валерьевна Бондаренко
Александр Васильевич Кучин
Ирина Юрьевна Чукичева
Original Assignee
Общество с ограниченной ответственностью "Диборнол Девелопмент"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Общество с ограниченной ответственностью "Диборнол Девелопмент" filed Critical Общество с ограниченной ответственностью "Диборнол Девелопмент"
Priority to RU2016138751A priority Critical patent/RU2016138751A/en
Priority to PCT/RU2017/050098 priority patent/WO2018063040A2/en
Publication of RU2016138751A publication Critical patent/RU2016138751A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (5)

1. Средство для лечения сердечно-сосудистых заболеваний, представляющее собой смесь двух изомеров 4-метил-2,6-диизоборнилфенола, где первый изомер представляет собой 2-{(1S,2R, 4R)-1,7,7-триметилбицикло[2.2.1]гепт-2-ил}, 6-{( 1R, 2S, 4S)-1,7,7-триметилбицикло[2.2.1]гепт-2-ил}-4-метилфенола (мезо-форма), второй изомер представляет собой рацемическую смесь 2,6- ди{(1R, 2S, 4S)-1, 7, 7-триметилбицикло[2.2.1]гепт-2-ил}-4-метилфенола} и 1. An agent for the treatment of cardiovascular diseases, which is a mixture of two isomers of 4-methyl-2,6-diisobornylphenol, where the first isomer is 2 - {(1S, 2R, 4R) -1,7,7-trimethylbicyclo [2.2 .1] hept-2-yl}, 6 - {(1R, 2S, 4S) -1,7,7-trimethylbicyclo [2.2.1] hept-2-yl} -4-methylphenol (meso form), the second the isomer is a racemic mixture of 2,6-di {(1R, 2S, 4S) -1, 7, 7-trimethylbicyclo [2.2.1] hept-2-yl} -4-methylphenol} and 2,6- ди{(1S, 2R, 4R)-1, 7, 7-триметилбицикло[2.2.1]гепт-2-ил}-4-метилфенола,2,6-di {(1S, 2R, 4R) -1, 7, 7-trimethylbicyclo [2.2.1] hept-2-yl} -4-methylphenol, при содержании в их смеси: when contained in their mixture: - первого изомера (мезо-форма) от 60 до 95 мас.%;- the first isomer (meso form) from 60 to 95 wt.%; - второго изомера (рацемическая смесь) от 40 до 5 мас.%. - the second isomer (racemic mixture) from 40 to 5 wt.%.
RU2016138751A 2016-09-30 2016-09-30 Cardiovascular Treatment RU2016138751A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
RU2016138751A RU2016138751A (en) 2016-09-30 2016-09-30 Cardiovascular Treatment
PCT/RU2017/050098 WO2018063040A2 (en) 2016-09-30 2017-09-30 Agent for treating cardiovascular diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2016138751A RU2016138751A (en) 2016-09-30 2016-09-30 Cardiovascular Treatment

Publications (1)

Publication Number Publication Date
RU2016138751A true RU2016138751A (en) 2018-04-02

Family

ID=61762967

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016138751A RU2016138751A (en) 2016-09-30 2016-09-30 Cardiovascular Treatment

Country Status (2)

Country Link
RU (1) RU2016138751A (en)
WO (1) WO2018063040A2 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101444489B1 (en) * 2007-02-01 2014-09-24 리스버로직스 코퍼레이션 Compounds for the prevention and treatment of cardiovascular diseases
RU2502719C2 (en) * 2011-07-06 2013-12-27 Учреждение Российской академии наук Институт химии Коми научного центра Уральского отделения РАН 2,6-diisobornylphenols
RU2555335C9 (en) * 2014-02-06 2016-09-10 Общество с ограниченной ответственностью "Диборнол Девелопмент" Medication for treatment of cardiovascular diseases

Also Published As

Publication number Publication date
WO2018063040A3 (en) 2018-05-03
WO2018063040A2 (en) 2018-04-05

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Legal Events

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HE9A Changing address for correspondence with an applicant
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20180821