RU2010123381A - Способ и композиции для диагностического применения у раковых пациентов - Google Patents
Способ и композиции для диагностического применения у раковых пациентов Download PDFInfo
- Publication number
- RU2010123381A RU2010123381A RU2010123381/15A RU2010123381A RU2010123381A RU 2010123381 A RU2010123381 A RU 2010123381A RU 2010123381/15 A RU2010123381/15 A RU 2010123381/15A RU 2010123381 A RU2010123381 A RU 2010123381A RU 2010123381 A RU2010123381 A RU 2010123381A
- Authority
- RU
- Russia
- Prior art keywords
- patient
- genes
- therapy
- addition
- gene products
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract 22
- 206010028980 Neoplasm Diseases 0.000 title claims 9
- 201000011510 cancer Diseases 0.000 title claims 3
- 239000000203 mixture Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 claims abstract 46
- 238000011122 anti-angiogenic therapy Methods 0.000 claims abstract 26
- 239000000523 sample Substances 0.000 claims abstract 25
- 238000011319 anticancer therapy Methods 0.000 claims abstract 11
- 208000008839 Kidney Neoplasms Diseases 0.000 claims abstract 10
- 206010038389 Renal cancer Diseases 0.000 claims abstract 10
- 201000010982 kidney cancer Diseases 0.000 claims abstract 10
- 239000013074 reference sample Substances 0.000 claims abstract 8
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims abstract 6
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims abstract 6
- 239000005557 antagonist Substances 0.000 claims abstract 6
- 229960000397 bevacizumab Drugs 0.000 claims abstract 3
- 150000001875 compounds Chemical class 0.000 claims 16
- 230000007012 clinical effect Effects 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 210000003734 kidney Anatomy 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 230000004083 survival effect Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 238000011282 treatment Methods 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98688407P | 2007-11-09 | 2007-11-09 | |
| US60/986,884 | 2007-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2010123381A true RU2010123381A (ru) | 2011-12-20 |
Family
ID=40342593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010123381/15A RU2010123381A (ru) | 2007-11-09 | 2008-11-05 | Способ и композиции для диагностического применения у раковых пациентов |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20090123930A1 (OSRAM) |
| EP (1) | EP2222874A2 (OSRAM) |
| JP (1) | JP2011502513A (OSRAM) |
| KR (1) | KR20100095571A (OSRAM) |
| CN (1) | CN101910416A (OSRAM) |
| AU (1) | AU2008324782A1 (OSRAM) |
| BR (1) | BRPI0817158A2 (OSRAM) |
| CA (1) | CA2703258A1 (OSRAM) |
| IL (1) | IL205246A0 (OSRAM) |
| MX (1) | MX2010005057A (OSRAM) |
| RU (1) | RU2010123381A (OSRAM) |
| WO (1) | WO2009061800A2 (OSRAM) |
| ZA (1) | ZA201002808B (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201510152RA (en) * | 2009-07-13 | 2016-01-28 | Genentech Inc | Diagnostic methods and compositions for treatment of cancer |
| MX2012002909A (es) * | 2009-09-17 | 2012-04-19 | Hoffmann La Roche | Metodos y composiciones para su uso en diagnostico de pacientes con cancer. |
| CN103109189A (zh) * | 2010-07-19 | 2013-05-15 | 霍夫曼-拉罗奇有限公司 | 鉴定响应抗癌疗法的可能性升高的患者的方法 |
| EP2596359A1 (en) * | 2010-07-19 | 2013-05-29 | F.Hoffmann-La Roche Ag | Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy |
| SG10201604497UA (en) * | 2011-06-02 | 2016-07-28 | Almac Diagnostics Ltd | Molecular Diagnostic Test For Cancer |
| AU2013207778B2 (en) * | 2012-01-13 | 2017-10-12 | Genentech, Inc. | Biological markers for identifying patients for treatment with VEGF antagonists |
| CN104364655A (zh) * | 2012-06-26 | 2015-02-18 | 霍夫曼-拉罗奇有限公司 | 贝伐单抗组合疗法用于治疗乳腺癌的血浆生物标志物 |
| CA2893033A1 (en) * | 2012-12-03 | 2014-06-12 | Almac Diagnostics Limited | Molecular diagnostic test for cancer |
| WO2015050500A1 (en) | 2013-09-17 | 2015-04-09 | Agency For Science, Technology And Research | Multigene assay for prognosis of renal cancer |
| GB201409479D0 (en) * | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| EP3230498B1 (en) * | 2014-12-09 | 2023-01-18 | Merck Sharp & Dohme LLC | System and methods for deriving gene signature biomarkers of response to pd-1 antagonists |
| KR101903522B1 (ko) * | 2015-11-25 | 2018-11-23 | 한국전자통신연구원 | 다차원 건강데이터에 대한 유사사례 검색 방법 및 그 장치 |
| US20250155442A1 (en) * | 2023-11-09 | 2025-05-15 | Sun Jet Biotechnology Inc. | Apolipoprotein a-ii biomarkers for detecting and monitoring cancers |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030027216A1 (en) * | 2001-07-02 | 2003-02-06 | Kiernan Urban A. | Analysis of proteins from biological fluids using mass spectrometric immunoassay |
| US8691506B2 (en) * | 2005-04-13 | 2014-04-08 | Oncotest Gmbh | Gene expression profiles being predictive for the response of tumors to pharmaceutically effective compounds |
| WO2007123722A2 (en) * | 2006-03-31 | 2007-11-01 | Bayer Healthcare Llc | Methods for prediction and prognosis of cancer, and monitoring cancer therapy |
-
2008
- 2008-11-05 BR BRPI0817158 patent/BRPI0817158A2/pt not_active IP Right Cessation
- 2008-11-05 CA CA2703258A patent/CA2703258A1/en not_active Abandoned
- 2008-11-05 EP EP08846956A patent/EP2222874A2/en not_active Withdrawn
- 2008-11-05 CN CN2008801243215A patent/CN101910416A/zh active Pending
- 2008-11-05 KR KR1020107012551A patent/KR20100095571A/ko not_active Withdrawn
- 2008-11-05 JP JP2010533204A patent/JP2011502513A/ja not_active Withdrawn
- 2008-11-05 WO PCT/US2008/082456 patent/WO2009061800A2/en not_active Ceased
- 2008-11-05 RU RU2010123381/15A patent/RU2010123381A/ru not_active Application Discontinuation
- 2008-11-05 AU AU2008324782A patent/AU2008324782A1/en not_active Abandoned
- 2008-11-05 MX MX2010005057A patent/MX2010005057A/es not_active Application Discontinuation
- 2008-11-05 US US12/265,143 patent/US20090123930A1/en not_active Abandoned
-
2010
- 2010-04-21 ZA ZA2010/02808A patent/ZA201002808B/en unknown
- 2010-04-22 IL IL205246A patent/IL205246A0/en unknown
- 2010-11-19 US US12/950,824 patent/US20110151468A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008324782A1 (en) | 2009-05-14 |
| US20090123930A1 (en) | 2009-05-14 |
| KR20100095571A (ko) | 2010-08-31 |
| EP2222874A2 (en) | 2010-09-01 |
| WO2009061800A3 (en) | 2009-07-16 |
| JP2011502513A (ja) | 2011-01-27 |
| CA2703258A1 (en) | 2009-05-14 |
| ZA201002808B (en) | 2011-07-27 |
| CN101910416A (zh) | 2010-12-08 |
| US20110151468A1 (en) | 2011-06-23 |
| IL205246A0 (en) | 2010-12-30 |
| MX2010005057A (es) | 2010-05-19 |
| WO2009061800A2 (en) | 2009-05-14 |
| BRPI0817158A2 (pt) | 2015-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20130729 |