RU2009143241A

RU2009143241A - METHOD FOR PHOTODYNAMIC THERAPY AND SURGICAL REMOVAL OF INNER-EYE NEW FORMATION

Info

Publication number: RU2009143241A
Application number: RU2009143241/14A
Authority: RU
Inventors: Юрий Александрович Белый (RU); Юрий Александрович Белый; Александр Владимирович Терещенко (RU); Александр Владимирович Терещенко
Priority date: 2009-11-25
Filing date: 2009-11-25
Publication date: 2011-05-27
Also published as: RU2433806C2

Abstract

Способ фотодинамической терапии и хирургического удаления внутриглазного новообразования, заключающийся в том, что за 2 часа до ФДТ пациенту внутривенно вводят ФС хлоринового ряда в дозе из расчета (0,8-1,1 мг/кг × 0,7) в течение 10 минут, за 10 минут до ФДТ пациенту внутривенно болюсно вводят тот же ФС в дозе из расчета (0,8-1,1 мг/кг × 0,3), перед вторым введением ФС над опухолью формируют поверхностный склеральный лоскут основанием от лимба толщиной 2/3 толщины склеры, через 10 минут после второго введения ФС облучают склеральное ложе при помощи насадки на световод лазерным излучением с длиной волны, соответствующей максимуму поглощения светового излучения хлориновым ФС, при плотности энергии 300 Дж/см2 с перекрытием соседних полей на 5% площади по завершении ФДТ опухоль удаляют транссклерально. The method of photodynamic therapy and surgical removal of an intraocular neoplasm, which consists in the fact that 2 hours before PDT the patient is intravenously injected with chlorine-type PS at a dose of (0.8-1.1 mg / kg × 0.7) for 10 minutes, 10 minutes before PDT, the same FS is administered to the patient intravenously in a dose based on the calculation (0.8-1.1 mg / kg × 0.3); before the second administration of PS, a superficial scleral flap with a 2/3 thick limb base is formed over the tumor scleral thickness, 10 minutes after the second injection of FS, the scleral bed is irradiated with a nozzle to the fiber with laser radiation with a wavelength corresponding to the maximum absorption of light by chlorine FS, at an energy density of 300 J / cm2 with overlapping adjacent fields by 5% of the area, after completion of PDT, the tumor is removed transclerally.

Claims

The method of photodynamic therapy and surgical removal of an intraocular neoplasm, which consists in the fact that 2 hours before PDT the patient is intravenously injected with chlorine-type PS at a dose of (0.8-1.1 mg / kg × 0.7) for 10 minutes, 10 minutes before PDT, the same FS is administered to the patient intravenously in a dose based on the calculation (0.8-1.1 mg / kg × 0.3); before the second administration of PS, a superficial scleral flap with a 2/3 thick limb base is formed over the tumor scleral thickness, 10 minutes after the second injection of FS, the scleral bed is irradiated with a nozzle to the fiber with laser radiation with a wavelength corresponding to the maximum absorption of light by chlorine FS, at an energy density of 300 J / cm ² with overlapping adjacent fields by 5% of the area, after completion of PDT, the tumor is removed transclerally.