RU2007121808A - Радиационная дозиметрия, блокирующие антитела: способы и применение в лечении рака - Google Patents

Радиационная дозиметрия, блокирующие антитела: способы и применение в лечении рака Download PDF

Info

Publication number
RU2007121808A
RU2007121808A RU2007121808/14A RU2007121808A RU2007121808A RU 2007121808 A RU2007121808 A RU 2007121808A RU 2007121808/14 A RU2007121808/14 A RU 2007121808/14A RU 2007121808 A RU2007121808 A RU 2007121808A RU 2007121808 A RU2007121808 A RU 2007121808A
Authority
RU
Russia
Prior art keywords
dose
resection cavity
hsrp
interest
surgically created
Prior art date
Application number
RU2007121808/14A
Other languages
English (en)
Russian (ru)
Inventor
Гамал АКАБАНИ-ХНЕЙДЕ (MX)
Гамал АКАБАНИ-ХНЕЙДЕ
Даррелл Д. БИГНЕР (US)
Даррелл Д. БИГНЕР
Майкл Р. ЗАЛУТСКИЙ (US)
Майкл Р. ЗАЛУТСКИЙ
Дэвид А. РИЦЦИЕРИ (US)
Дэвид А. РИЦЦИЕРИ
Original Assignee
Дюк Юниверсити (Us)
Дюк Юниверсити
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дюк Юниверсити (Us), Дюк Юниверсити filed Critical Дюк Юниверсити (Us)
Publication of RU2007121808A publication Critical patent/RU2007121808A/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1066Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014Intracavitary radiation therapy
    • A61N5/1015Treatment of resected cavities created by surgery, e.g. lumpectomy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
RU2007121808/14A 2004-11-17 2005-11-17 Радиационная дозиметрия, блокирующие антитела: способы и применение в лечении рака RU2007121808A (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US62890204P 2004-11-17 2004-11-17
US62874004P 2004-11-17 2004-11-17
US60/628,740 2004-11-17
US60/628,902 2004-11-17
PCT/US2005/041884 WO2006073586A2 (en) 2004-11-17 2005-11-17 Radiation dosimetry and blocking antibodies and methods and uses threfor in the treatment of cancer

Publications (1)

Publication Number Publication Date
RU2007121808A true RU2007121808A (ru) 2008-12-27

Family

ID=36647943

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007121808/14A RU2007121808A (ru) 2004-11-17 2005-11-17 Радиационная дозиметрия, блокирующие антитела: способы и применение в лечении рака

Country Status (8)

Country Link
US (1) US20060127311A1 (enExample)
EP (1) EP1817062A4 (enExample)
JP (1) JP2008520707A (enExample)
AU (1) AU2005323377A1 (enExample)
CA (1) CA2587172A1 (enExample)
RU (1) RU2007121808A (enExample)
WO (1) WO2006073586A2 (enExample)
ZA (1) ZA200704642B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2681790A1 (en) * 2007-03-30 2008-10-09 F. Hoffmann-La Roche Ag Composition of labeled and non-labeled monoclonal antibodies
CN114404429B (zh) * 2021-11-30 2023-06-30 重庆医科大学附属第二医院 一种纳米银修饰的单宁酸-铁网络的载药纳米复合物及其制备方法和逆转肿瘤耐药应用
WO2024181576A1 (ja) * 2023-03-02 2024-09-06 日本メジフィジックス株式会社 放射性金属標識抗体、放射性医薬、及び化合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) * 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
USRE38008E1 (en) * 1986-10-09 2003-02-25 Neorx Corporation Methods for improved targeting of antibody, antibody fragments, hormones and other targeting agents, and conjugates thereof
US6787153B1 (en) * 1991-06-28 2004-09-07 Mitsubishi Chemical Corporation Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
US6749853B1 (en) * 1992-03-05 2004-06-15 Board Of Regents, The University Of Texas System Combined methods and compositions for coagulation and tumor treatment
AU6445894A (en) * 1993-03-19 1994-10-11 Duke University Method of treatment of tumors with an antibody binding to tenascin
GB9314623D0 (en) * 1993-07-14 1993-08-25 Nordion Int Inc Localization and therapy with agents directed against prostate specific antigen in breast cancer
US5874540A (en) * 1994-10-05 1999-02-23 Immunomedics, Inc. CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
US6022521A (en) * 1995-05-04 2000-02-08 The Regents Of The University Of Michigan Method of establishing the optimal radiation dose for radiopharmaceutical treatment of disease
WO1999036105A2 (en) * 1998-01-16 1999-07-22 Mca Development B.V. USE OF RADIOLABELED MONOCLONAL IgM IN THERAPY FOR CANCER AND AUTOIMMUNE DISEASE
ATE281184T1 (de) * 1998-06-04 2004-11-15 Coulter Pharm Inc Patientenspezifische dosimetrie
ATE230614T1 (de) * 1998-07-13 2003-01-15 Univ Texas Krebsbehandlung mit aminophospholipide bindenden, therapeutischen konjugaten
US20020187100A1 (en) * 2000-12-21 2002-12-12 David Rizzieri Anti-tenascin monoclonal antibody therapy for lymphoma
US6455026B1 (en) * 2001-03-23 2002-09-24 Agy Therapeutics, Inc. Use of protein tyrosine phosphatase zeta as a biomolecular target in the treatment and visualization of brain tumors
US7011814B2 (en) * 2001-04-23 2006-03-14 Sicel Technologies, Inc. Systems, methods and devices for in vivo monitoring of a localized response via a radiolabeled analyte in a subject

Also Published As

Publication number Publication date
ZA200704642B (en) 2008-07-30
EP1817062A2 (en) 2007-08-15
EP1817062A4 (en) 2010-01-20
WO2006073586A2 (en) 2006-07-13
WO2006073586A8 (en) 2007-02-22
US20060127311A1 (en) 2006-06-15
CA2587172A1 (en) 2006-07-13
AU2005323377A1 (en) 2006-07-13
JP2008520707A (ja) 2008-06-19
WO2006073586A3 (en) 2006-11-23

Similar Documents

Publication Publication Date Title
Chua et al. Emerging technologies for local cancer treatment
Stewart et al. Intraperitoneal yttrium-90-labeled monoclonal antibody in ovarian cancer.
JP5889337B2 (ja) Mriマーカー、送達および抜取りシステムならびにこれらの製造方法および使用方法
Riva et al. Local treatment of malignant gliomas by direct infusion of specific monoclonal antibodies labeled with 131I: comparison of the results obtained in recurrent and newly diagnosed tumors
Kobayashi et al. Application of a macromolecular contrast agent for detection of alterations of tumor vessel permeability induced by radiation
KR20100014809A (ko) 열치료 서셉터 및 이를 사용하는 방법
Howell Advancements in the use of Auger electrons in science and medicine during the period 2015–2019
US20060204443A1 (en) Methods for tumor treatment using dendrimer conjugates
EP0240990B1 (en) Method and apparatus for selective irradiation of biological materials
Wu et al. Multimodal in vivo tracking of chimeric antigen receptor T cells in preclinical glioblastoma models
AU2017283151A1 (en) Modified dextran conjugates comprising a lysine-urea-glutamate pharmacophore
JP6073508B2 (ja) デンドリマー組成物、合成方法、及びそれらの使用
CN101321542A (zh) 用于微动脉成像和放射治疗的微颗粒
Martínez‐Rovira et al. Monte Carlo dose enhancement studies in microbeam radiation therapy
RU2007121808A (ru) Радиационная дозиметрия, блокирующие антитела: способы и применение в лечении рака
JP7431940B2 (ja) 腫瘍を治療するための方法
Klingebiel et al. [131I]-Metaiodobenzylguanidine in the treatment of metastatic neuroblastoma: Clinical, pharmacological and dosimetric aspects
US20070280418A1 (en) Coupled Carriers for Enhancing Therapy
Chen et al. Imaging, biodistribution and efficacy evaluation of 188Re-human serum albumin microspheres via intraarterial route in an orthotopic hepatoma model
Kim et al. Direct and indirect chimeric antigen receptor T-Cell imaging with PET/MRI in a tumor xenograft model
TWI833803B (zh) 含有高z元素之奈米顆粒在製備用於治療腫瘤之藥物之用途
WO2021230369A1 (ja) 金ナノ粒子含有医薬
JP2008540429A (ja) 癌の治療における併用療法
US8709380B1 (en) Targeting agents for enhancing radiation therapy
Vallera et al. Radioimmunotherapy of CD22-expressing Daudi tumors in nude mice with a 90Y-labeled anti-CD22 monoclonal antibody

Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20100115