RU2006105648A - Композиции для очистки и кристаллизации представляющих интерес молекул - Google Patents
Композиции для очистки и кристаллизации представляющих интерес молекул Download PDFInfo
- Publication number
- RU2006105648A RU2006105648A RU2006105648/13A RU2006105648A RU2006105648A RU 2006105648 A RU2006105648 A RU 2006105648A RU 2006105648/13 A RU2006105648/13 A RU 2006105648/13A RU 2006105648 A RU2006105648 A RU 2006105648A RU 2006105648 A RU2006105648 A RU 2006105648A
- Authority
- RU
- Russia
- Prior art keywords
- molecule
- interest
- coordinating
- composition
- target
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 22
- 238000002425 crystallisation Methods 0.000 title claims 3
- 230000008025 crystallization Effects 0.000 title claims 3
- 238000004140 cleaning Methods 0.000 title 1
- 239000003446 ligand Substances 0.000 claims 16
- 210000004027 cell Anatomy 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 150000002500 ions Chemical class 0.000 claims 8
- 239000000523 sample Substances 0.000 claims 5
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 150000007523 nucleic acids Chemical group 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 239000002244 precipitate Substances 0.000 claims 3
- 108090001008 Avidin Proteins 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 230000000536 complexating effect Effects 0.000 claims 2
- 239000013078 crystal Substances 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 230000005847 immunogenicity Effects 0.000 claims 2
- 238000011534 incubation Methods 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL157086 | 2003-07-24 | ||
| IL15708603A IL157086A0 (en) | 2003-07-24 | 2003-07-24 | Multivalent ligand complexes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2006105648A true RU2006105648A (ru) | 2006-07-27 |
Family
ID=32652285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006105648/13A RU2006105648A (ru) | 2003-07-24 | 2004-07-22 | Композиции для очистки и кристаллизации представляющих интерес молекул |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060121519A1 (https=) |
| EP (1) | EP1648995A4 (https=) |
| JP (1) | JP2007515384A (https=) |
| KR (1) | KR20060037337A (https=) |
| CN (1) | CN101415721A (https=) |
| CA (1) | CA2531492A1 (https=) |
| IL (2) | IL157086A0 (https=) |
| MX (1) | MXPA06000944A (https=) |
| NO (1) | NO20060400L (https=) |
| RU (1) | RU2006105648A (https=) |
| SG (1) | SG145760A1 (https=) |
| WO (1) | WO2005010141A2 (https=) |
| ZA (1) | ZA200600315B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7956165B2 (en) | 2003-07-24 | 2011-06-07 | Affisink Biotechnology Ltd. | Compositions and methods for purifying and crystallizing molecules of interest |
| WO2006085321A2 (en) * | 2005-02-10 | 2006-08-17 | Affisink Biotechnology Ltd. | Compositions and methods for purifying and crystallizing molecules of interest |
| FR2902799B1 (fr) | 2006-06-27 | 2012-10-26 | Millipore Corp | Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide |
| US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
| WO2008079302A2 (en) * | 2006-12-21 | 2008-07-03 | Millipore Corporation | Purification of proteins |
| US8569464B2 (en) | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
| US20100233714A1 (en) * | 2007-11-13 | 2010-09-16 | Beadling Leslie C | Multistate affinity ligands for the separation and purification of antibodies, antibody fragments and conjugates of |
| WO2009078018A2 (en) * | 2007-12-17 | 2009-06-25 | Affisink Biotechnology Ltd. | Methods for purifying or depleting molecules or cells of interest |
| US8999702B2 (en) | 2008-06-11 | 2015-04-07 | Emd Millipore Corporation | Stirred tank bioreactor |
| JP2012511929A (ja) | 2008-12-16 | 2012-05-31 | イー・エム・デイー・ミリポア・コーポレイシヨン | 攪拌タンク反応器及び方法 |
| CA2791918C (en) | 2010-03-05 | 2019-11-19 | Boehringer Ingelheim International Gmbh | Selective enrichment of antibodies |
| WO2011146394A1 (en) | 2010-05-17 | 2011-11-24 | Millipore Corporation | Stimulus responsive polymers for the purification of biomolecules |
| US10030224B2 (en) | 2015-11-01 | 2018-07-24 | Ariel-University Research And Development Company Ltd. | Methods of analyzing cell membranes |
| WO2021152584A1 (en) | 2020-01-28 | 2021-08-05 | Ariel Scientific Innovations Ltd. | Methods of analyzing cell membranes |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4036945A (en) * | 1976-05-03 | 1977-07-19 | The Massachusetts General Hospital | Composition and method for determining the size and location of myocardial infarcts |
| US4331647A (en) * | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
| US5215927A (en) * | 1986-01-30 | 1993-06-01 | Fred Hutchinson Cancer Research Center | Method for immunoselection of cells using avidin and biotin |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US6740734B1 (en) * | 1994-01-14 | 2004-05-25 | Biovitrum Ab | Bacterial receptor structures |
| SE9400088D0 (sv) * | 1994-01-14 | 1994-01-14 | Kabi Pharmacia Ab | Bacterial receptor structures |
| US6017719A (en) * | 1994-06-14 | 2000-01-25 | Nexell Therapeutics, Inc. | Positive and positive/negative cell selection mediated by peptide release |
| US20010008766A1 (en) * | 1998-03-17 | 2001-07-19 | Sylvia Daunert | Quantitative binding assays using green fluorescent protein as a label |
| US6589503B1 (en) * | 1998-06-20 | 2003-07-08 | Washington University | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
| US7198930B2 (en) * | 2000-02-29 | 2007-04-03 | Millennium Pharmaceuticals, Inc. | Human protein kinase, phosphatase, and protease family members and uses thereof |
| DE60231801D1 (de) * | 2001-04-23 | 2009-05-14 | Mallinckrodt Inc | Tc und re markierte radioaktive glycosylierte octreotid-derivate |
| US20040265921A1 (en) * | 2003-06-30 | 2004-12-30 | National University Of Singapore | Intein-mediated attachment of ligands to proteins for immobilization onto a support |
| US7956165B2 (en) * | 2003-07-24 | 2011-06-07 | Affisink Biotechnology Ltd. | Compositions and methods for purifying and crystallizing molecules of interest |
-
2003
- 2003-07-24 IL IL15708603A patent/IL157086A0/xx unknown
-
2004
- 2004-07-22 SG SG200806175-6A patent/SG145760A1/en unknown
- 2004-07-22 WO PCT/IL2004/000669 patent/WO2005010141A2/en not_active Ceased
- 2004-07-22 MX MXPA06000944A patent/MXPA06000944A/es not_active Application Discontinuation
- 2004-07-22 KR KR1020067000635A patent/KR20060037337A/ko not_active Withdrawn
- 2004-07-22 CA CA002531492A patent/CA2531492A1/en not_active Abandoned
- 2004-07-22 CN CNA2004800263533A patent/CN101415721A/zh active Pending
- 2004-07-22 RU RU2006105648/13A patent/RU2006105648A/ru not_active Application Discontinuation
- 2004-07-22 JP JP2006520982A patent/JP2007515384A/ja active Pending
- 2004-07-22 EP EP04745009A patent/EP1648995A4/en not_active Withdrawn
-
2006
- 2006-01-12 IL IL173107A patent/IL173107A0/en unknown
- 2006-01-12 ZA ZA200600315A patent/ZA200600315B/xx unknown
- 2006-01-12 US US11/330,112 patent/US20060121519A1/en not_active Abandoned
- 2006-01-25 NO NO20060400A patent/NO20060400L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20060121519A1 (en) | 2006-06-08 |
| EP1648995A2 (en) | 2006-04-26 |
| WO2005010141A2 (en) | 2005-02-03 |
| CA2531492A1 (en) | 2005-02-03 |
| ZA200600315B (en) | 2007-04-25 |
| EP1648995A4 (en) | 2010-03-10 |
| WO2005010141A3 (en) | 2009-03-26 |
| NO20060400L (no) | 2006-03-27 |
| KR20060037337A (ko) | 2006-05-03 |
| SG145760A1 (en) | 2008-09-29 |
| IL173107A0 (en) | 2006-06-11 |
| MXPA06000944A (es) | 2006-03-30 |
| CN101415721A (zh) | 2009-04-22 |
| JP2007515384A (ja) | 2007-06-14 |
| IL157086A0 (en) | 2004-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20090512 |