RU2006101889A - Таблетка, содержащая флувастатин и кармеллозу кальция - Google Patents
Таблетка, содержащая флувастатин и кармеллозу кальция Download PDFInfo
- Publication number
- RU2006101889A RU2006101889A RU2006101889/15A RU2006101889A RU2006101889A RU 2006101889 A RU2006101889 A RU 2006101889A RU 2006101889/15 A RU2006101889/15 A RU 2006101889/15A RU 2006101889 A RU2006101889 A RU 2006101889A RU 2006101889 A RU2006101889 A RU 2006101889A
- Authority
- RU
- Russia
- Prior art keywords
- approximately
- tablet
- fluvastatin
- talc
- crystalline cellulose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Claims (12)
1. Таблетка, содержащая флувастатин, отличающаяся тем, что в качестве разрыхлителя она содержит кармеллозу кальция.
2. Таблетка по п.1, которая содержит фармацевтически приемлемое щелочное вещество, обеспечивающее рН водного раствора или дисперсии указанной таблетки по меньшей мере 8.
3. Таблетка по п.2, в которой щелочное вещество является карбонатом.
4. Таблетка по одному из пп.1-3, на которую нанесена оболочка.
5. Таблетка по одному из пп.1-3, содержащая кристаллическую целлюлозу в качестве разбавителя.
6. Таблетка по п.5, на которую нанесена оболочка.
7. Таблетка флувастатина по п.1, содержащая, мг:
8. Таблетка флувастатина по п.1, содержащая, мг:
9. Таблетка флувастатина по п.1, содержащая, мг:
10. Таблетка флувастатина по п.1, содержащая, мг:
в сердцевине таблетки:
в пленочной оболочке:
11. Таблетка флувастатина по пп.7-10, отличающаяся тем, что время ее распада составляет от примерно 10 до 30 мин.
12. Таблетка по одному из пп.7-10, на которую нанесена оболочка.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003-181349 | 2003-06-25 | ||
| JP2003181349 | 2003-06-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006101889A true RU2006101889A (ru) | 2007-08-10 |
| RU2361582C2 RU2361582C2 (ru) | 2009-07-20 |
Family
ID=33549526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006101889/15A RU2361582C2 (ru) | 2003-06-25 | 2004-06-24 | Таблетка, содержащая флувастатин и кармеллозу кальция |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20090117181A1 (ru) |
| EP (1) | EP1641440B1 (ru) |
| KR (1) | KR20060030480A (ru) |
| CN (1) | CN1809342A (ru) |
| AT (1) | ATE471713T1 (ru) |
| AU (1) | AU2004251439B2 (ru) |
| BR (1) | BRPI0411855A (ru) |
| CA (1) | CA2529447A1 (ru) |
| CO (1) | CO5650224A2 (ru) |
| DE (1) | DE602004027808D1 (ru) |
| EC (1) | ECSP056238A (ru) |
| IL (1) | IL172531A0 (ru) |
| IS (1) | IS8249A (ru) |
| MA (1) | MA27889A1 (ru) |
| MX (1) | MXPA05013943A (ru) |
| NO (1) | NO20060261L (ru) |
| NZ (1) | NZ544119A (ru) |
| RU (1) | RU2361582C2 (ru) |
| TN (1) | TNSN05330A1 (ru) |
| WO (1) | WO2005000276A1 (ru) |
| ZA (1) | ZA200509930B (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2642195A1 (en) * | 2006-02-24 | 2007-09-07 | Teva Pharmaceutical Industries Ltd. | Fluvastatin sodium pharmaceutical compositions |
| US9744127B2 (en) * | 2010-10-12 | 2017-08-29 | Bayer Intellectual Property Gmbh | Non-starch based soft chewables |
| JP5988963B2 (ja) | 2011-04-12 | 2016-09-07 | 沢井製薬株式会社 | ピタバスタチン含有製剤及びその製造方法 |
| CN102309452B (zh) * | 2011-09-14 | 2013-01-23 | 海南美大制药有限公司 | 氟伐他汀钠脂质体固体制剂 |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| CN104069502B (zh) * | 2013-03-29 | 2018-02-16 | 北京罗诺强施医药技术研发中心有限公司 | 复合骨架材料及其药物组合物 |
| CN104095850B (zh) * | 2013-04-03 | 2019-04-05 | 深圳信立泰药业股份有限公司 | 一种稳定的匹伐他汀钙药物组合物及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4739073A (en) * | 1983-11-04 | 1988-04-19 | Sandoz Pharmaceuticals Corp. | Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof |
| HU9203780D0 (en) * | 1991-12-12 | 1993-03-29 | Sandoz Ag | Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them |
| GB9703388D0 (en) * | 1997-02-18 | 1997-04-09 | Sandoz Yakuhin K K Tokyo Sykk | Organic compounds |
| AR035016A1 (es) * | 1999-08-25 | 2004-04-14 | Takeda Chemical Industries Ltd | Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima. |
| EP1254667A4 (en) * | 2000-02-10 | 2003-03-12 | Takeda Chemical Industries Ltd | MEDICINE COMPRISING A COMBINATION |
| US20020025952A1 (en) * | 2000-07-06 | 2002-02-28 | American Home Products Corporation | Combinations of statins, estrogens and estrogenic agents |
| WO2002030400A1 (fr) * | 2000-10-06 | 2002-04-18 | Takeda Chemical Industries, Ltd. | Preparations solides |
-
2004
- 2004-06-24 US US10/560,940 patent/US20090117181A1/en not_active Abandoned
- 2004-06-24 NZ NZ544119A patent/NZ544119A/en unknown
- 2004-06-24 CA CA002529447A patent/CA2529447A1/en not_active Abandoned
- 2004-06-24 EP EP04740278A patent/EP1641440B1/en not_active Expired - Lifetime
- 2004-06-24 KR KR1020057024682A patent/KR20060030480A/ko not_active Application Discontinuation
- 2004-06-24 WO PCT/EP2004/006865 patent/WO2005000276A1/en not_active Application Discontinuation
- 2004-06-24 CN CNA2004800174031A patent/CN1809342A/zh active Pending
- 2004-06-24 MX MXPA05013943A patent/MXPA05013943A/es unknown
- 2004-06-24 RU RU2006101889/15A patent/RU2361582C2/ru not_active IP Right Cessation
- 2004-06-24 BR BRPI0411855-3A patent/BRPI0411855A/pt not_active IP Right Cessation
- 2004-06-24 AU AU2004251439A patent/AU2004251439B2/en not_active Ceased
- 2004-06-24 DE DE602004027808T patent/DE602004027808D1/de not_active Expired - Fee Related
- 2004-06-24 AT AT04740278T patent/ATE471713T1/de not_active IP Right Cessation
-
2005
- 2005-12-07 ZA ZA200509930A patent/ZA200509930B/en unknown
- 2005-12-12 IL IL172531A patent/IL172531A0/en unknown
- 2005-12-19 EC EC2005006238A patent/ECSP056238A/es unknown
- 2005-12-21 MA MA28679A patent/MA27889A1/fr unknown
- 2005-12-23 TN TNP2005000330A patent/TNSN05330A1/en unknown
- 2005-12-27 CO CO05130257A patent/CO5650224A2/es not_active Application Discontinuation
-
2006
- 2006-01-18 NO NO20060261A patent/NO20060261L/no not_active Application Discontinuation
- 2006-01-20 IS IS8249A patent/IS8249A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO5650224A2 (es) | 2006-06-30 |
| DE602004027808D1 (de) | 2010-08-05 |
| MXPA05013943A (es) | 2006-02-24 |
| EP1641440B1 (en) | 2010-06-23 |
| ATE471713T1 (de) | 2010-07-15 |
| NO20060261L (no) | 2006-01-18 |
| ECSP056238A (es) | 2006-04-19 |
| ZA200509930B (en) | 2007-01-31 |
| IS8249A (is) | 2006-01-20 |
| IL172531A0 (en) | 2006-04-10 |
| RU2361582C2 (ru) | 2009-07-20 |
| TNSN05330A1 (en) | 2007-07-10 |
| EP1641440A1 (en) | 2006-04-05 |
| NZ544119A (en) | 2008-04-30 |
| BRPI0411855A (pt) | 2006-08-29 |
| AU2004251439A1 (en) | 2005-01-06 |
| MA27889A1 (fr) | 2006-05-02 |
| WO2005000276A1 (en) | 2005-01-06 |
| US20090117181A1 (en) | 2009-05-07 |
| AU2004251439B2 (en) | 2008-09-11 |
| KR20060030480A (ko) | 2006-04-10 |
| CA2529447A1 (en) | 2005-01-06 |
| CN1809342A (zh) | 2006-07-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20050142196A1 (en) | Stable pharmaceutical compositions containing an ACE inhibitor | |
| US6316460B1 (en) | Pharmaceutical compositions | |
| RU2548673C2 (ru) | Фармацевтическая композиция, содержащая производное хинолина | |
| MY152185A (en) | Modified release 1-[(3-hydroxy-adamant-1-ylamino)-acetyl]-pyrrolidine-2(s)-carbonitrile formulation | |
| RU2006101889A (ru) | Таблетка, содержащая флувастатин и кармеллозу кальция | |
| RS20120514A2 (en) | ONE-DAY OXYCODON FORMULATIONS | |
| NO20024891L (no) | Farmasöytiske sammensetninger | |
| MXPA02003977A (es) | Inhibidores de adhesion de celula mediada por al°2. | |
| US20070254030A1 (en) | Formulations of Ramipril | |
| BG66115B1 (bg) | Използване на рамиприл или негова фармацевтично приемлива сол за предотвратяване на конгестивна сърдечна недостатъчност | |
| US20140271492A1 (en) | Manufacturing Process for Effervescent Dosage Forms | |
| US11786526B2 (en) | Pharmaceutical composition comprising rosuvastatin and ezetimibe and a preparation method thereof | |
| US7598233B2 (en) | Method for treating thrombosis | |
| IS7208A (is) | Snöggbráðnandi lyfjagjafarform til inntöku um munn | |
| RU2008139625A (ru) | Композиции и способы лечения ревматоидного артрита | |
| SK106094A3 (en) | Pharmaceutical agent | |
| US7867514B2 (en) | Method for stabilizing preparation | |
| NO20004545L (no) | FremgangsmÕte for fremstilling av (R)-<alfa>-(2,3- dimetoksyfenyl)-1-[2-(4-fluorofenyl)etyl]-4-piperidinmetanol | |
| DK166259B (da) | Oral tablet til ph-uafhaengig frigivelse | |
| IL292696A (en) | Methods for the treatment and/or prevention of severe harmful cardiovascular events with a combination of a bromodomain bet inhibitor and a sodium-dependent glucose transporter 2 inhibitor | |
| JP2012036129A (ja) | 安定なアトルバスタチン製剤の設計 | |
| RU2362549C2 (ru) | Таблетки в оболочке | |
| RU2479310C2 (ru) | Фармацевтическая композиция для лечения артериальной гипертензии и застойной сердечной недостаточности и способ ее получения | |
| RU2008147739A (ru) | Комбинированная противотуберкулезная фармацевтическая композиция | |
| US20210393532A1 (en) | Preparation containing saxagliptin and method for producing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20110625 |