RU2004125594A - Применение тиболона при лечение симптомов, связанных с введением лекарств, препятствующих синтезу эндогенного эстрогена - Google Patents
Применение тиболона при лечение симптомов, связанных с введением лекарств, препятствующих синтезу эндогенного эстрогена Download PDFInfo
- Publication number
- RU2004125594A RU2004125594A RU2004125594/14A RU2004125594A RU2004125594A RU 2004125594 A RU2004125594 A RU 2004125594A RU 2004125594/14 A RU2004125594/14 A RU 2004125594/14A RU 2004125594 A RU2004125594 A RU 2004125594A RU 2004125594 A RU2004125594 A RU 2004125594A
- Authority
- RU
- Russia
- Prior art keywords
- symptoms
- estrogen
- synthesis
- treatment
- endogenous estrogen
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims 6
- 230000015572 biosynthetic process Effects 0.000 title claims 5
- 229940011871 estrogen Drugs 0.000 title claims 5
- 239000000262 estrogen Substances 0.000 title claims 5
- 238000003786 synthesis reaction Methods 0.000 title claims 5
- 208000024891 symptom Diseases 0.000 claims 8
- 206010030247 Oestrogen deficiency Diseases 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 229940122815 Aromatase inhibitor Drugs 0.000 claims 4
- 239000003886 aromatase inhibitor Substances 0.000 claims 4
- WZDGZWOAQTVYBX-XOINTXKNSA-N tibolone Chemical compound C([C@@H]12)C[C@]3(C)[C@@](C#C)(O)CC[C@H]3[C@@H]1[C@H](C)CC1=C2CCC(=O)C1 WZDGZWOAQTVYBX-XOINTXKNSA-N 0.000 claims 4
- 229960001023 tibolone Drugs 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 3
- BFYIZQONLCFLEV-DAELLWKTSA-N Aromasine Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=C)C2=C1 BFYIZQONLCFLEV-DAELLWKTSA-N 0.000 claims 2
- 206010065687 Bone loss Diseases 0.000 claims 2
- 206010027304 Menopausal symptoms Diseases 0.000 claims 2
- 229960003437 aminoglutethimide Drugs 0.000 claims 2
- ROBVIMPUHSLWNV-UHFFFAOYSA-N aminoglutethimide Chemical group C=1C=C(N)C=CC=1C1(CC)CCC(=O)NC1=O ROBVIMPUHSLWNV-UHFFFAOYSA-N 0.000 claims 2
- 229960002932 anastrozole Drugs 0.000 claims 2
- YBBLVLTVTVSKRW-UHFFFAOYSA-N anastrozole Chemical compound N#CC(C)(C)C1=CC(C(C)(C#N)C)=CC(CN2N=CN=C2)=C1 YBBLVLTVTVSKRW-UHFFFAOYSA-N 0.000 claims 2
- 229960000255 exemestane Drugs 0.000 claims 2
- 229960004421 formestane Drugs 0.000 claims 2
- OSVMTWJCGUFAOD-KZQROQTASA-N formestane Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1O OSVMTWJCGUFAOD-KZQROQTASA-N 0.000 claims 2
- 229960003881 letrozole Drugs 0.000 claims 2
- HPJKCIUCZWXJDR-UHFFFAOYSA-N letrozole Chemical compound C1=CC(C#N)=CC=C1C(N1N=CN=C1)C1=CC=C(C#N)C=C1 HPJKCIUCZWXJDR-UHFFFAOYSA-N 0.000 claims 2
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 1
- 229960005309 estradiol Drugs 0.000 claims 1
- 229930182833 estradiol Natural products 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02075235.8 | 2002-01-22 | ||
| EP02075235 | 2002-01-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2004125594A true RU2004125594A (ru) | 2005-03-10 |
Family
ID=27589110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004125594/14A RU2004125594A (ru) | 2002-01-22 | 2003-01-16 | Применение тиболона при лечение симптомов, связанных с введением лекарств, препятствующих синтезу эндогенного эстрогена |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20050124592A1 (https=) |
| EP (1) | EP1469861A1 (https=) |
| JP (1) | JP2005518412A (https=) |
| KR (1) | KR20040073572A (https=) |
| CN (1) | CN1620298A (https=) |
| BR (1) | BR0306789A (https=) |
| CA (1) | CA2472240A1 (https=) |
| EC (1) | ECSP045179A (https=) |
| HR (1) | HRP20040635A2 (https=) |
| IL (1) | IL162769A0 (https=) |
| IS (1) | IS7338A (https=) |
| MX (1) | MXPA04007071A (https=) |
| PL (1) | PL371181A1 (https=) |
| RU (1) | RU2004125594A (https=) |
| WO (1) | WO2003061665A1 (https=) |
| ZA (1) | ZA200405262B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0302572D0 (en) | 2003-02-05 | 2003-03-12 | Astrazeneca Ab | Method of treatment |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE63051B1 (en) * | 1989-03-18 | 1995-03-22 | Akzo Nv | Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn- 3-one |
| EP0613687B1 (en) * | 1993-03-05 | 1999-06-02 | Akzo Nobel N.V. | Use of a pregnane derivatives for the treatment of tumours |
| EP1102755B1 (en) * | 1998-08-07 | 2006-01-04 | Chiron Corporation | Substituted isoxazole derivatives as estrogen receptor modulators |
-
2003
- 2003-01-16 HR HR20040635A patent/HRP20040635A2/hr not_active Application Discontinuation
- 2003-01-16 KR KR10-2004-7011160A patent/KR20040073572A/ko not_active Withdrawn
- 2003-01-16 CN CNA038025108A patent/CN1620298A/zh active Pending
- 2003-01-16 JP JP2003561609A patent/JP2005518412A/ja active Pending
- 2003-01-16 CA CA002472240A patent/CA2472240A1/en not_active Abandoned
- 2003-01-16 BR BR0306789-0A patent/BR0306789A/pt not_active IP Right Cessation
- 2003-01-16 EP EP20030731620 patent/EP1469861A1/en not_active Withdrawn
- 2003-01-16 IL IL16276903A patent/IL162769A0/xx unknown
- 2003-01-16 MX MXPA04007071A patent/MXPA04007071A/es not_active Application Discontinuation
- 2003-01-16 US US10/502,444 patent/US20050124592A1/en not_active Abandoned
- 2003-01-16 PL PL03371181A patent/PL371181A1/xx not_active Application Discontinuation
- 2003-01-16 WO PCT/EP2003/000373 patent/WO2003061665A1/en not_active Ceased
- 2003-01-16 RU RU2004125594/14A patent/RU2004125594A/ru not_active Application Discontinuation
-
2004
- 2004-06-28 IS IS7338A patent/IS7338A/is unknown
- 2004-07-01 ZA ZA2004/05262A patent/ZA200405262B/en unknown
- 2004-07-06 EC EC2004005179A patent/ECSP045179A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003061665A1 (en) | 2003-07-31 |
| JP2005518412A (ja) | 2005-06-23 |
| HRP20040635A2 (en) | 2004-10-31 |
| ZA200405262B (en) | 2005-08-31 |
| PL371181A1 (en) | 2005-06-13 |
| CA2472240A1 (en) | 2003-07-31 |
| MXPA04007071A (es) | 2004-10-29 |
| CN1620298A (zh) | 2005-05-25 |
| IS7338A (is) | 2004-06-28 |
| IL162769A0 (en) | 2005-11-20 |
| BR0306789A (pt) | 2004-12-28 |
| EP1469861A1 (en) | 2004-10-27 |
| KR20040073572A (ko) | 2004-08-19 |
| US20050124592A1 (en) | 2005-06-09 |
| ECSP045179A (es) | 2004-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20060719 |