RU2004112186A - METHOD FOR PRODUCING BONE ALLOTRANSPLANT FOR REPLACEMENT OF SKULL BONE DEFECTS - Google Patents

METHOD FOR PRODUCING BONE ALLOTRANSPLANT FOR REPLACEMENT OF SKULL BONE DEFECTS Download PDF

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Publication number
RU2004112186A
RU2004112186A RU2004112186/15A RU2004112186A RU2004112186A RU 2004112186 A RU2004112186 A RU 2004112186A RU 2004112186/15 A RU2004112186/15 A RU 2004112186/15A RU 2004112186 A RU2004112186 A RU 2004112186A RU 2004112186 A RU2004112186 A RU 2004112186A
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RU
Russia
Prior art keywords
bone
allotransplant
replacement
producing
skull
Prior art date
Application number
RU2004112186/15A
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Russian (ru)
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RU2279281C2 (en
Inventor
Михаил Васильевич Лекишвили (RU)
Михаил Васильевич Лекишвили
Максим Геннадьевич Васильев (RU)
Максим Геннадьевич Васильев
Оксана Юрьевна Баракина (RU)
Оксана Юрьевна Баракина
Елена Давидовна Горбунова (RU)
Елена Давидовна Горбунова
Александр Сергеевич Панкратов (RU)
Александр Сергеевич Панкратов
Original Assignee
Михаил Васильевич Лекишвили (RU)
Михаил Васильевич Лекишвили
Максим Геннадьевич Васильев (RU)
Максим Геннадьевич Васильев
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Application filed by Михаил Васильевич Лекишвили (RU), Михаил Васильевич Лекишвили, Максим Геннадьевич Васильев (RU), Максим Геннадьевич Васильев filed Critical Михаил Васильевич Лекишвили (RU)
Priority to RU2004112186/15A priority Critical patent/RU2279281C2/en
Publication of RU2004112186A publication Critical patent/RU2004112186A/en
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Publication of RU2279281C2 publication Critical patent/RU2279281C2/en

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Claims (1)

Способ получения костного аллотрансплантата для черепно-лицевой пластики, включающий механическую обработку, обезжиривание, деминерализацию, замораживание, лиофилизацию, стерилизацию, отличающийся тем, что в качестве аллотрансплантата используют кости свода черепа, при этом деминерализацию осуществляют до 83-94%, а замораживание проводят в физиологическом растворе при температуре -30-35°С в течение 24-72 ч с 3-5-кратным размораживанием и сменой физиологического раствора.A method of producing a bone allograft for craniofacial plasty, including mechanical processing, degreasing, demineralization, freezing, lyophilization, sterilization, characterized in that the cranial vaults are used as an allograft, while demineralization is carried out up to 83-94%, and freezing is carried out in saline solution at a temperature of -30-35 ° C for 24-72 hours with 3-5 times defrosting and a change of saline solution.
RU2004112186/15A 2004-04-22 2004-04-22 Method for obtaining osseous allotransplant for substituting defects of cranial bones RU2279281C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2004112186/15A RU2279281C2 (en) 2004-04-22 2004-04-22 Method for obtaining osseous allotransplant for substituting defects of cranial bones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2004112186/15A RU2279281C2 (en) 2004-04-22 2004-04-22 Method for obtaining osseous allotransplant for substituting defects of cranial bones

Publications (2)

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RU2004112186A true RU2004112186A (en) 2005-10-10
RU2279281C2 RU2279281C2 (en) 2006-07-10

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RU2004112186/15A RU2279281C2 (en) 2004-04-22 2004-04-22 Method for obtaining osseous allotransplant for substituting defects of cranial bones

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2527167C1 (en) * 2013-02-20 2014-08-27 Александр Григорьевич Волков Method for preoperative preparation for demineralised bone graft for plasty in experiment
UA115089C2 (en) 2015-11-04 2017-09-11 Товариство З Обмеженою Відповідальністю "А.А. Партнерс" MEDICAL PRODUCT BASED ON HUMAN CELLS FOR THE CORRECTION OF OSTEOREPRATIVE PROCESSES

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RU2279281C2 (en) 2006-07-10

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Effective date: 20060423