RU2002109480A - Редокс-обратимые HCV белки с конформацией, подобной нативной - Google Patents
Редокс-обратимые HCV белки с конформацией, подобной нативнойInfo
- Publication number
- RU2002109480A RU2002109480A RU2002109480/13A RU2002109480A RU2002109480A RU 2002109480 A RU2002109480 A RU 2002109480A RU 2002109480/13 A RU2002109480/13 A RU 2002109480/13A RU 2002109480 A RU2002109480 A RU 2002109480A RU 2002109480 A RU2002109480 A RU 2002109480A
- Authority
- RU
- Russia
- Prior art keywords
- amino acid
- functionally equivalent
- hcv
- hcv protein
- equivalent portion
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title claims 22
- 108090000623 proteins and genes Proteins 0.000 title claims 22
- 235000018102 proteins Nutrition 0.000 claims 21
- 235000001014 amino acid Nutrition 0.000 claims 19
- 150000001413 amino acids Chemical class 0.000 claims 14
- 230000000694 effects Effects 0.000 claims 4
- 230000002441 reversible effect Effects 0.000 claims 4
- -1 Cys amino acids Chemical class 0.000 claims 3
- 102000004316 Oxidoreductases Human genes 0.000 claims 3
- 108090000854 Oxidoreductases Proteins 0.000 claims 3
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 238000011953 bioanalysis Methods 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229940021993 prophylactic vaccine Drugs 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 229940021747 therapeutic vaccine Drugs 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
- C07K16/109—Hepatitis C virus; Hepatitis G virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99870225.2 | 1999-10-27 | ||
| EP99870225 | 1999-10-27 | ||
| US16928899P | 1999-12-07 | 1999-12-07 | |
| US60/169,288 | 1999-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2002109480A true RU2002109480A (ru) | 2004-03-10 |
Family
ID=30129297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2002109480/13A RU2002109480A (ru) | 1999-10-27 | 2000-10-25 | Редокс-обратимые HCV белки с конформацией, подобной нативной |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1224214A1 (hu) |
| JP (1) | JP2003513022A (hu) |
| CN (1) | CN1384839A (hu) |
| AU (1) | AU1144501A (hu) |
| BR (1) | BR0015170A (hu) |
| CA (1) | CA2387666A1 (hu) |
| CZ (1) | CZ20021819A3 (hu) |
| HU (1) | HUP0203195A3 (hu) |
| MX (1) | MXPA02004052A (hu) |
| NZ (1) | NZ518095A (hu) |
| PL (1) | PL354990A1 (hu) |
| RU (1) | RU2002109480A (hu) |
| WO (1) | WO2001030815A1 (hu) |
| ZA (1) | ZA200203169B (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001273348A1 (en) | 2000-07-10 | 2002-01-21 | Diosynth Rtp, Inc. | Purification of human troponin i |
| EP1381671A2 (en) | 2001-04-24 | 2004-01-21 | Innogenetics N.V. | Constructs and methods for expression of recombinant hcv envelope proteins |
| EP1481984A1 (en) * | 2003-05-28 | 2004-12-01 | Innogenetics N.V. | Modified hepatitis C virus (HCV) NS5 |
| BR112015023355A8 (pt) * | 2013-03-14 | 2018-01-30 | Abbott Lab | antígenos recombinantes ns3 de hcv e mutantes dos mesmos para detecção de anticorpos aprimorada. |
| EP3756648A1 (en) * | 2019-06-27 | 2020-12-30 | Imnate Sarl | Improved vaccine formulations |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4734362A (en) * | 1986-02-03 | 1988-03-29 | Cambridge Bioscience Corporation | Process for purifying recombinant proteins, and products thereof |
| AU652919B2 (en) * | 1989-06-02 | 1994-09-15 | Genetic Systems Corporation | Cysteine thiol-protected peptides for use in immunoassays |
| US6150134A (en) * | 1994-07-29 | 2000-11-21 | Innogenetics, N.V. | Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use |
| GB9703406D0 (en) * | 1997-02-19 | 1997-04-09 | Chiron Spa | Expression of heterologous proteins |
| EP0947525A1 (en) * | 1998-03-27 | 1999-10-06 | Innogenetics N.V. | Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of HCV viral antigen in host tissue |
-
2000
- 2000-10-25 HU HU0203195A patent/HUP0203195A3/hu unknown
- 2000-10-25 WO PCT/EP2000/010499 patent/WO2001030815A1/en active Search and Examination
- 2000-10-25 PL PL00354990A patent/PL354990A1/xx not_active Application Discontinuation
- 2000-10-25 CZ CZ20021819A patent/CZ20021819A3/cs unknown
- 2000-10-25 EP EP00972863A patent/EP1224214A1/en not_active Withdrawn
- 2000-10-25 NZ NZ518095A patent/NZ518095A/en unknown
- 2000-10-25 JP JP2001533812A patent/JP2003513022A/ja active Pending
- 2000-10-25 MX MXPA02004052A patent/MXPA02004052A/es unknown
- 2000-10-25 BR BR0015170-0A patent/BR0015170A/pt not_active IP Right Cessation
- 2000-10-25 CN CN00814993A patent/CN1384839A/zh active Pending
- 2000-10-25 CA CA002387666A patent/CA2387666A1/en not_active Abandoned
- 2000-10-25 RU RU2002109480/13A patent/RU2002109480A/ru not_active Application Discontinuation
- 2000-10-25 AU AU11445/01A patent/AU1144501A/en not_active Abandoned
-
2002
- 2002-04-22 ZA ZA200203169A patent/ZA200203169B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ518095A (en) | 2003-09-26 |
| WO2001030815A1 (en) | 2001-05-03 |
| MXPA02004052A (es) | 2002-11-07 |
| EP1224214A1 (en) | 2002-07-24 |
| CA2387666A1 (en) | 2001-05-03 |
| CN1384839A (zh) | 2002-12-11 |
| ZA200203169B (en) | 2003-09-23 |
| BR0015170A (pt) | 2002-06-25 |
| CZ20021819A3 (cs) | 2003-06-18 |
| AU1144501A (en) | 2001-05-08 |
| PL354990A1 (en) | 2004-03-22 |
| HUP0203195A3 (en) | 2004-07-28 |
| HUP0203195A2 (hu) | 2002-12-28 |
| JP2003513022A (ja) | 2003-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20050321 |