RU1811400C - Composition for prevention of diseases in mouth - Google Patents

Abstract

Usage: in medicine, namely in dentistry. Essence: in addition to the known components (water, ethyl alcohol, perfume, menthol, etc.) it contains kelp extract in combination with polyvinylpyrrolidone, sodium lauryl sulfate and preservative antiseptic. Positive effect: a combination of these components ensures the activity of the composition by improving the permeability and trophism of periodontal tissues, as well as by enhancing the mineralization of tooth enamel, increasing the resistance of dental tissues, and eliminating inflammatory phenomena in periodontal tissues. 2 tab.

Description

The invention relates to medicine, namely to dentistry.

An object of the invention is to provide a composition for the prevention of oral diseases. which significantly improves the cleaning of teeth, healing and trophism of periodontal tissues and oral mucosa, and also promotes the mineralization of tooth enamel, which generally provides a preventive effect.

The proposed composition contains an aqueous extract of kelp, polyvinylpyrrolidone, sodium lauryl sulfate, antiseptic, menthol, ethyl alcohol, perfume and water.

Kelp water extract contains a small amount of chlorophyll, carotenoids, macroelements (potassium, magnesium, calcium), microelements (iron, zinc, silver, copper, vanadium, tin, etc.), amino acids, including essential and other biologically active substances. They penetrate through the mucous membrane of the cavity

the mouth and contact with it, have a pronounced healing effect, enhance trophism and microcirculation of periodontal tissues, eliminate inflammation, and also contribute to the mineralization of tooth enamel, providing a preventive effect in general.

Polyvinylpyrrolidone promotes the dissolution of the protein-lipid base of dental plaque, which provides a significant improvement in cleaning teeth from plaque, and consequently, enhances the mineralization of enamel and trophism of periodontal tissues, i.e. enhances the preventive effect of the proposed structure.

Sodium lauryl sulfate is a powerful surfactant and provides improved detergent, cleaning properties of the proposed method. However, in optimal concentrations (1.0-2.5%), it provides an improvement in the permeability of the mucous membrane of the cavity

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mouth and tooth enamel for macro and micronutrients, chlorophyll and vitamins. This makes it possible in general to provide a highly effective composition for the prevention of oral diseases.

The composition is prepared as follows.

In half the amount of hot water (70-80 ° C), the entire amount of polyvinylpyrrolidone is dissolved. After cooling the water to 30-40 ° C., A portion of sodium auryl sulfate and preservative antiseptic are dissolved. Menthol is dissolved in a basic ethanol solution. Then both solutions are mixed and the remaining components are added: an aqueous extract of kelp, perfume and the rest of the water. The solution was stirred, filtered and packaged in vials.

In accordance with the method of preparation of the composition, the example shows the maximum dosage of the components. In example 2, the composition is prepared as in example 1, but the components are taken in the optimal (middle) ratio. Example 3 shows data on the preparation of a composition with a minimum content of components (see table).

Use the composition as follows. . :

K1 / 2 cups of warm (3 (L40 ° C) water, add 15-20 drops of the composition and vigorously rinse the mouth, holding the solution in the mouth for 15-20 seconds to improve the effect of biologically active components on the oral mucosa , periodontal tissues and tooth enamel, as well as for the dissolution of dental deposits. It is used 2-3 times a day after eating and pre-brushing your teeth.

When used for applications on the gum, the composition is diluted in a ratio of 1:20, in the resulting solution, cotton swabs are moistened, which are applied to the gums for 15-20 minutes, the course of procedures is 10-12 days / ...... -. ; . .; .-;

P r and m r. Sick, 38 years old, suffers from chronic catarrhal gingivitis, complaints of bleeding, hyperemia, itching, soreness. Objective research results: hygiene index 2.6 points; I-deck RMA - 38.5%; Schiller's test - Pisarev - is positive; durability of capillary gums 27s.

After thorough removal of dental plaque, applications were performed with a solution of the composition for 10 days, and mouth rinses were prescribed 2 times a day. After 14 days of using the proposed composition, the gum condition improved significantly: no complaints, bleeding disappeared

bone, itching, soreness and inflammation (Schiller-Pisarev test is negative), the PMA index decreased to 12.8%, the hygiene index improved (1.7 points), and the resistance of the gingival capillaries increased for 35 s. After 3.0 days of observation, signs of improvement continued to increase: no complaints, hygiene index decreased to 1.4 points; RMA index was only 9.3%; Schiller-Pisarev test is negative and the resistance of the gingival capillaries reached -39 s. . : ..

PRI me R 2. Sick, 23 years old, complained of bleeding gums, sore teeth, frequent loss of fillings. Diagnosis: chronic catarrhal gingivitis, multiple dental caries (KPU-10), dentin hyperesthesia.

Objective studies: hygiene index-2.5 points; RMA index-29.7%; Schiller's test - Pisarev - is positive; durability of capillary gums-28 s; enamel resistance test-8 points.

After removing the dental deposits of the patient, 15 applications of the solution of the composition on the teeth and gums were carried out, rinses with the composition 2-3 times a day were prescribed. After 16 days of using the new composition, the patient showed no complaints., Bleeding gums and signs of inflammation disappeared, dentine hyperesthesia decreased (Schiller-Pisarev test was negative; PMA index was 14.2%; hygiene index was 1.6 points), capill resistance the gingival ditch increased to 38 s, the enamel resistance temperature changed little and amounted to 7 points.

: After 35 days of observation, signs of improvement in periodontal conditions increased: the hygiene index improved (1.3 points), there were no signs of inflammation (PMA index 8.3%; Schiller-Pisarev test negative), capillary resistance reached 41 s, dentine hyperesthesia disappeared, and the enamel resistance test improved and amounted to 6 points. Thus, the above examples indicate a positive effect of the new composition on periodontal tissues and teeth.

The proposed composition was applied in 30 patients. The results of these observations are presented in table.2.

Thus, the use of the proposed composition for the prevention of oral diseases has significantly improved the processes of microcirculation and trophism of periodontal tissues, strengthen (mineralize) tooth enamel, which is confirmed by objective indicators: the hygiene index decreased by 35-40% (, 01). the PMA index, which characterizes inflammation, decreases

it was more than doubled (, 001), the resistance of the gingival capillaries, indicating an improvement in periodontal trophism, increased by 40-45% (, 01). Significantly, enamel mineralization improved by 30-35% (, 01).

Claims (1)

The invention is a composition for the prevention of diseases of the oral cavity, containing a plant extract, ethyl alcohol, menthol, perfume and water, characterized in that, in order to increase activity by improving the permeability of the oral mucosa and trophism of periodontal tissues, as well as enhancing the mineralization of tooth enamel, it additionally contains polyvinyl vinyl pyrrolidone, sodium lauryl sulfate. antiseptic, and as a plant component use an aqueous extract of kelp in the next quantitative content of the components, May. %: Laminaria extract 5.0-10.0; polyvinylpyrrolidone 3.5-5.0; sodium lauryl sulfate 1.0-2.5; antiseptic preservative 0.3-0.5; (propyl ether paraoxybenzoic acids or sodium benzoate) ethyl alcohol 96 ° 10.0-15.0; menthol 1.2-2.0; perfume 0.7-1.5; waterfall 100. Table table 2