RS61222B1 - Ciklopiroks, ciklopiroksolamin, ili prolek ciklopiroksa za upotrebu u lečenju kancera bešike - Google Patents

Ciklopiroks, ciklopiroksolamin, ili prolek ciklopiroksa za upotrebu u lečenju kancera bešike

Info

Publication number
RS61222B1
RS61222B1 RS20201438A RSP20201438A RS61222B1 RS 61222 B1 RS61222 B1 RS 61222B1 RS 20201438 A RS20201438 A RS 20201438A RS P20201438 A RSP20201438 A RS P20201438A RS 61222 B1 RS61222 B1 RS 61222B1
Authority
RS
Serbia
Prior art keywords
ciclopirox
treatment
prodrug
bladder cancer
olamine
Prior art date
Application number
RS20201438A
Other languages
English (en)
Inventor
Scott J Weir
Shrikant Anant
Original Assignee
Univ Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kansas filed Critical Univ Kansas
Publication of RS61222B1 publication Critical patent/RS61222B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RS20201438A 2014-11-11 2015-11-10 Ciklopiroks, ciklopiroksolamin, ili prolek ciklopiroksa za upotrebu u lečenju kancera bešike RS61222B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462078069P 2014-11-11 2014-11-11
US201562134747P 2015-03-18 2015-03-18
PCT/US2015/059955 WO2016077346A1 (en) 2014-11-11 2015-11-10 Methods of bladder cancer treatment with ciclopirox, ciclopirox olamine, or a ciclopirox prodrug
EP15859268.3A EP3217980B1 (en) 2014-11-11 2015-11-10 Ciclopirox, ciclopirox olamine, or a ciclopirox prodrug for use in the treatment of bladder cancer

Publications (1)

Publication Number Publication Date
RS61222B1 true RS61222B1 (sr) 2021-01-29

Family

ID=55954945

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20201438A RS61222B1 (sr) 2014-11-11 2015-11-10 Ciklopiroks, ciklopiroksolamin, ili prolek ciklopiroksa za upotrebu u lečenju kancera bešike

Country Status (11)

Country Link
US (1) US20170304329A1 (sr)
EP (1) EP3217980B1 (sr)
JP (1) JP2017533952A (sr)
CN (2) CN116687941A (sr)
DK (1) DK3217980T3 (sr)
ES (1) ES2836208T3 (sr)
HR (1) HRP20201893T1 (sr)
HU (1) HUE052670T2 (sr)
PT (1) PT3217980T (sr)
RS (1) RS61222B1 (sr)
WO (1) WO2016077346A1 (sr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112351970A (zh) * 2018-05-30 2021-02-09 科莱恩国际有限公司 2-羟基吡啶-1-氧化物或其衍生物的形成方法
WO2020040327A1 (ko) * 2018-08-23 2020-02-27 광주과학기술원 시클로피록스의 hbv 코어조립 저해 용도
WO2021078937A1 (en) * 2019-10-25 2021-04-29 Deutsches Krebsforschungszentrum Treatment of stat3 related diseases by iron chelators
EP4193989A1 (en) 2021-12-09 2023-06-14 Atlas Molecular Pharma, S.L. A formulation for an effective oral administration of ciclopirox with no adversal gasterointestinal toxicity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1051181B1 (en) 1997-12-31 2004-03-17 The University Of Kansas Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof
AU2003251875A1 (en) * 2002-07-15 2004-02-02 Combinatorx, Incorporated Combination therapy for the treatment of neoplasms
WO2010048712A1 (en) 2008-10-31 2010-05-06 University Health Network Ciclopirox and cytarabine for the treatment of leukemic disorders
HUE028411T2 (en) 2010-12-02 2016-12-28 Univ Kansas Precursors and derivatives of 6-cyclohexyl-1-hydroxy-4-methylpyridin-2 (1H) -one \ t

Also Published As

Publication number Publication date
HRP20201893T1 (hr) 2021-02-05
PT3217980T (pt) 2020-12-11
WO2016077346A1 (en) 2016-05-19
ES2836208T3 (es) 2021-06-24
EP3217980A4 (en) 2018-05-02
CN107206012A (zh) 2017-09-26
EP3217980B1 (en) 2020-10-14
CN116687941A (zh) 2023-09-05
US20170304329A1 (en) 2017-10-26
JP2017533952A (ja) 2017-11-16
HUE052670T2 (hu) 2021-05-28
EP3217980A1 (en) 2017-09-20
DK3217980T3 (da) 2020-12-07

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