RS55258B1 - Korišćenje anti-cd20 antitela tipa ii sa povećanom ćelijskom citotoksičnošću zavisnom od antitela (adcc) u kombinaciji sa ciklofosfamidom, vinkristinom i doksorubicinom za lečenje non-hodgkinovih limfoma - Google Patents
Korišćenje anti-cd20 antitela tipa ii sa povećanom ćelijskom citotoksičnošću zavisnom od antitela (adcc) u kombinaciji sa ciklofosfamidom, vinkristinom i doksorubicinom za lečenje non-hodgkinovih limfomaInfo
- Publication number
- RS55258B1 RS55258B1 RS20160864A RSP20160864A RS55258B1 RS 55258 B1 RS55258 B1 RS 55258B1 RS 20160864 A RS20160864 A RS 20160864A RS P20160864 A RSP20160864 A RS P20160864A RS 55258 B1 RS55258 B1 RS 55258B1
- Authority
- RS
- Serbia
- Prior art keywords
- antibody
- doxorubicine
- adcc
- lymphomas
- vincristine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/664—Amides of phosphorus acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08005554 | 2008-03-25 | ||
| EP08007172 | 2008-04-11 | ||
| PCT/EP2009/002111 WO2009118142A1 (en) | 2008-03-25 | 2009-03-23 | Use of a type ii anti-cd20 antibody with increased antibody dependent cellular cytotoxicity (adcc) in combination with cyclophosphamide, vincristine and doxorubicine for treating non-hodgkin' s lymphomas |
| EP09723808.3A EP2268310B1 (en) | 2008-03-25 | 2009-03-23 | Use of a type ii anti-cd20 antibody with increased antibody dependent cellular cytotoxicity (adcc) in combination with cyclophosphamide, vincristine and doxorubicine for treating non-hodgkin' s lymphomas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS55258B1 true RS55258B1 (sr) | 2017-02-28 |
Family
ID=40872445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20160864A RS55258B1 (sr) | 2008-03-25 | 2009-03-23 | Korišćenje anti-cd20 antitela tipa ii sa povećanom ćelijskom citotoksičnošću zavisnom od antitela (adcc) u kombinaciji sa ciklofosfamidom, vinkristinom i doksorubicinom za lečenje non-hodgkinovih limfoma |
Country Status (31)
| Country | Link |
|---|---|
| US (6) | US20090246197A1 (sr) |
| EP (1) | EP2268310B1 (sr) |
| JP (3) | JP5547709B2 (sr) |
| KR (1) | KR101280716B1 (sr) |
| CN (2) | CN101983071A (sr) |
| AR (1) | AR072947A1 (sr) |
| AU (1) | AU2009228616B2 (sr) |
| BR (1) | BRPI0909227B8 (sr) |
| CA (1) | CA2716884C (sr) |
| CL (1) | CL2009000713A1 (sr) |
| CR (1) | CR11687A (sr) |
| CY (1) | CY1117984T1 (sr) |
| DK (1) | DK2268310T3 (sr) |
| ES (1) | ES2592312T3 (sr) |
| HR (1) | HRP20161301T1 (sr) |
| HU (1) | HUE028828T2 (sr) |
| IL (1) | IL208018A (sr) |
| LT (1) | LT2268310T (sr) |
| MA (1) | MA32140B1 (sr) |
| MX (1) | MX2010009647A (sr) |
| MY (1) | MY163544A (sr) |
| NZ (1) | NZ587284A (sr) |
| PE (1) | PE20091821A1 (sr) |
| PL (1) | PL2268310T3 (sr) |
| PT (1) | PT2268310T (sr) |
| RS (1) | RS55258B1 (sr) |
| RU (1) | RU2589704C2 (sr) |
| SI (1) | SI2268310T1 (sr) |
| TW (1) | TWI500624B (sr) |
| WO (1) | WO2009118142A1 (sr) |
| ZA (1) | ZA201006190B (sr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ME03330B (me) | 2003-11-05 | 2019-10-20 | Roche Glycart Ag | Cd20 antitijela sa povećanim afinitetom za vezivanje fc receptora i efektornom funkcijom |
| WO2009118142A1 (en) * | 2008-03-25 | 2009-10-01 | F. Hoffmann-La Roche Ag | Use of a type ii anti-cd20 antibody with increased antibody dependent cellular cytotoxicity (adcc) in combination with cyclophosphamide, vincristine and doxorubicine for treating non-hodgkin' s lymphomas |
| TW201014605A (en) | 2008-09-16 | 2010-04-16 | Genentech Inc | Methods for treating progressive multiple sclerosis |
| AR078161A1 (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
| MY191929A (en) | 2010-06-03 | 2022-07-18 | Pharmacyclics Llc | The use of inhibitors of bruton's tyrosine kinase (btk) |
| KR20130088170A (ko) * | 2010-12-16 | 2013-08-07 | 로슈 글리카트 아게 | 비푸코실화 ｃｄ20 항체와 ｍｄｍ2 저해제와의 조합 치료 |
| US20130302274A1 (en) * | 2011-11-25 | 2013-11-14 | Roche Glycart Ag | Combination therapy |
| CN104704129A (zh) | 2012-07-24 | 2015-06-10 | 药品循环公司 | 与对布鲁顿酪氨酸激酶(btk)抑制剂的抗性相关的突变 |
| JP2017501157A (ja) * | 2013-12-17 | 2017-01-12 | ジェネンテック， インコーポレイテッド | Ｐｄ−１軸結合アンタゴニスト及び抗ｃｄ２０抗体を使用してがんを治療する方法 |
| US9603927B2 (en) * | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| CR20170086A (es) | 2014-09-09 | 2017-05-22 | Janssen Biotech Inc | Terapias de combinación con anticuerpos anti-cd38 |
| EP3227338A4 (en) | 2014-12-04 | 2018-05-16 | Janssen Biotech, Inc. | Anti-cd38 antibodies for treatment of acute myeloid leukemia |
| KR102602754B1 (ko) | 2015-05-20 | 2023-11-14 | 얀센 바이오테크 인코포레이티드 | 경쇄 아밀로이드증 및 다른 cd38-양성 혈액학적 악성종양을 치료하기 위한 항-cd38 항체 |
| MX2018000265A (es) | 2015-06-22 | 2018-05-23 | Janssen Biotech Inc | Terapias de combinacion para enfermedades malignas hematologicas con anticuerpos anti-cd38 e inhibidores de survivina. |
| US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| KR20180067693A (ko) | 2015-11-03 | 2018-06-20 | 얀센 바이오테크 인코포레이티드 | 항-cd38 항체의 피하 제제 및 이의 용도 |
| US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
| EP3386549A4 (en) * | 2015-12-10 | 2019-08-07 | City of Hope | ANTIBODIES COUPLED WITH CYANINE WITH CELL PENETRATION |
| US10525083B2 (en) | 2016-10-07 | 2020-01-07 | Novartis Ag | Nucleic acid molecules encoding chimeric antigen receptors comprising a CD20 binding domain |
| JP2020508436A (ja) | 2016-12-07 | 2020-03-19 | プロジェニティ， インコーポレイテッド | 胃腸管の検出方法、装置およびシステム |
| WO2018183929A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| MA50514A (fr) | 2017-10-31 | 2020-09-09 | Janssen Biotech Inc | Méthodes de traitement du myélome multiple à haut risque |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| CN116726362A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| TW202126689A (zh) * | 2019-10-04 | 2021-07-16 | 日商中外製藥股份有限公司 | 抑制具奧比妥珠單株抗體耐受性的cd20陽性癌之細胞增殖的藥劑，及其相關之醫藥組成物、醫藥、製造、抑制細胞增殖的方法、治療方法、ii型抗cd20抗體、化合物及其組合、增強劑以及誘導劑 |
| EP4309722A2 (en) | 2019-12-13 | 2024-01-24 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5736137A (en) * | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| ATE458007T1 (de) * | 1998-04-20 | 2010-03-15 | Glycart Biotechnology Ag | Glykosylierungs-engineering von antikörpern zur verbesserung der antikörperabhängigen zellvermittelten zytotoxizität |
| RU2306952C2 (ru) * | 2001-01-31 | 2007-09-27 | Байоджен Айдек Инк. | Лечение в-клеточных злокачественных опухолей с использованием комбинации применений, связанных с антителами, уменьшающими количество b-клеток, и с иммуномодулирующими антителами |
| AU2003301445A1 (en) * | 2002-10-17 | 2004-05-04 | Genmab A/S | Human monoclonal antibodies against cd20 |
| ES2633311T3 (es) * | 2002-12-16 | 2017-09-20 | Genentech, Inc. | Variantes de inmunoglobulina y usos de las mismas |
| ME03330B (me) * | 2003-11-05 | 2019-10-20 | Roche Glycart Ag | Cd20 antitijela sa povećanim afinitetom za vezivanje fc receptora i efektornom funkcijom |
| DOP2006000029A (es) * | 2005-02-07 | 2006-08-15 | Genentech Inc | Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas) |
| CN101282993A (zh) * | 2005-06-02 | 2008-10-08 | 阿斯利康公司 | 针对cd20的抗体和其用途 |
| KR101460932B1 (ko) * | 2005-08-26 | 2014-11-12 | 로슈 글리카트 아게 | 변형된 세포 신호 활성을 가진 개질된 항원 결합 분자 |
| US20110243931A1 (en) * | 2007-09-02 | 2011-10-06 | Thomas Friess | Combination therapy with type i and type ii anti-cd20 antibodies |
| WO2009118142A1 (en) * | 2008-03-25 | 2009-10-01 | F. Hoffmann-La Roche Ag | Use of a type ii anti-cd20 antibody with increased antibody dependent cellular cytotoxicity (adcc) in combination with cyclophosphamide, vincristine and doxorubicine for treating non-hodgkin' s lymphomas |
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2009
- 2009-03-23 WO PCT/EP2009/002111 patent/WO2009118142A1/en active Application Filing
- 2009-03-23 LT LTEP09723808.3T patent/LT2268310T/lt unknown
- 2009-03-23 HU HUE09723808A patent/HUE028828T2/en unknown
- 2009-03-23 CA CA2716884A patent/CA2716884C/en active Active
- 2009-03-23 RS RS20160864A patent/RS55258B1/sr unknown
- 2009-03-23 DK DK09723808.3T patent/DK2268310T3/en active
- 2009-03-23 CN CN2009801101810A patent/CN101983071A/zh active Pending
- 2009-03-23 AU AU2009228616A patent/AU2009228616B2/en active Active
- 2009-03-23 KR KR1020107021332A patent/KR101280716B1/ko active IP Right Grant
- 2009-03-23 CN CN201611215290.7A patent/CN107198772A/zh active Pending
- 2009-03-23 CL CL2009000713A patent/CL2009000713A1/es unknown
- 2009-03-23 PT PT97238083T patent/PT2268310T/pt unknown
- 2009-03-23 ES ES09723808.3T patent/ES2592312T3/es active Active
- 2009-03-23 NZ NZ587284A patent/NZ587284A/en unknown
- 2009-03-23 EP EP09723808.3A patent/EP2268310B1/en active Active
- 2009-03-23 TW TW098109412A patent/TWI500624B/zh active
- 2009-03-23 AR ARP090101035A patent/AR072947A1/es unknown
- 2009-03-23 RU RU2010143454/15A patent/RU2589704C2/ru active
- 2009-03-23 PL PL09723808T patent/PL2268310T3/pl unknown
- 2009-03-23 MY MYPI2010004461A patent/MY163544A/en unknown
- 2009-03-23 BR BRPI0909227A patent/BRPI0909227B8/pt active IP Right Grant
- 2009-03-23 MX MX2010009647A patent/MX2010009647A/es active IP Right Grant
- 2009-03-23 SI SI200931530A patent/SI2268310T1/sl unknown
- 2009-03-23 JP JP2011501133A patent/JP5547709B2/ja active Active
- 2009-03-23 US US12/408,746 patent/US20090246197A1/en not_active Abandoned
- 2009-03-24 PE PE2009000437A patent/PE20091821A1/es not_active Application Discontinuation
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2010
- 2010-05-10 US US12/777,141 patent/US20100310581A1/en not_active Abandoned
- 2010-08-30 ZA ZA2010/06190A patent/ZA201006190B/en unknown
- 2010-09-03 MA MA33145A patent/MA32140B1/fr unknown
- 2010-09-06 IL IL208018A patent/IL208018A/en active IP Right Grant
- 2010-09-23 CR CR11687A patent/CR11687A/es unknown
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2011
- 2011-03-07 US US13/042,305 patent/US20110177067A1/en not_active Abandoned
- 2011-10-28 US US13/284,415 patent/US20120301459A1/en not_active Abandoned
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2013
- 2013-03-14 US US13/829,409 patent/US20140065134A1/en not_active Abandoned
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2014
- 2014-01-24 JP JP2014011332A patent/JP5912142B2/ja active Active
- 2014-06-05 US US14/297,478 patent/US20160000911A1/en not_active Abandoned
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2016
- 2016-03-18 JP JP2016055096A patent/JP6154039B2/ja active Active
- 2016-09-07 CY CY20161100889T patent/CY1117984T1/el unknown
- 2016-10-10 HR HRP20161301TT patent/HRP20161301T1/hr unknown
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