RO88071B1 - Derivat de 2,3-ditiochinoxalina si procedeu de obtinere a acestuia - Google Patents
Derivat de 2,3-ditiochinoxalina si procedeu de obtinere a acestuiaInfo
- Publication number
- RO88071B1 RO88071B1 RO112849A RO11284983A RO88071B1 RO 88071 B1 RO88071 B1 RO 88071B1 RO 112849 A RO112849 A RO 112849A RO 11284983 A RO11284983 A RO 11284983A RO 88071 B1 RO88071 B1 RO 88071B1
- Authority
- RO
- Romania
- Prior art keywords
- derivative
- ditioquinoxaline
- preparing
- same
- refluxing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000010992 reflux Methods 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- YFBUDXNMBTUSOC-UHFFFAOYSA-N 1,4-dihydroquinoxaline-2,3-dithione Chemical class C1=CC=C2NC(=S)C(=S)NC2=C1 YFBUDXNMBTUSOC-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 229960000583 acetic acid Drugs 0.000 abstract 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 229940088623 biologically active substance Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000012362 glacial acetic acid Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Inventia se refera la un derivat de 2,3-ditio-chinoxalina si la un procedeu de obtinere a acestuia, substanta cu actiune anticancerigena, antivirala, antifungica si biologic activa în dismetaboliile SH, cristalina, de culoare maron-închisa, instabila în prezenta aerului solubila în dimetilformamida, dimetilsulfoxid si dioxan, cu punct de topire 231 degree C. Procedeul pentru obtinerea substantei, conform inventiei, realizeaza sinteza prin refluxarea timp de 2h pe baia de apa a unei solutii de 2,3-diclor-7amino-chioxalina si de tiouree, izolarea produsului facîndu-se prin alcalinizarea solutiei, refluxarea ei timp de înca 2h si tratarea în final cu acid acetic glacial.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO83112349A RO88071A2 (ro) | 1983-12-14 | 1983-12-14 | Derivat de 2,3-ditio-chinoxalina si procedeu de obtinere a acestuia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO83112349A RO88071A2 (ro) | 1983-12-14 | 1983-12-14 | Derivat de 2,3-ditio-chinoxalina si procedeu de obtinere a acestuia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO88071B1 true RO88071B1 (ro) | 1985-11-01 |
| RO88071A2 RO88071A2 (ro) | 1985-11-30 |
Family
ID=20114018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO83112349A RO88071A2 (ro) | 1983-12-14 | 1983-12-14 | Derivat de 2,3-ditio-chinoxalina si procedeu de obtinere a acestuia |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO88071A2 (ro) |
-
1983
- 1983-12-14 RO RO83112349A patent/RO88071A2/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO88071A2 (ro) | 1985-11-30 |
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