RO84119B1 - Procedeu de obtinere a 4(5)-nitroimidazolului - Google Patents
Procedeu de obtinere a 4(5)-nitroimidazoluluiInfo
- Publication number
- RO84119B1 RO84119B1 RO106264A RO10626482A RO84119B1 RO 84119 B1 RO84119 B1 RO 84119B1 RO 106264 A RO106264 A RO 106264A RO 10626482 A RO10626482 A RO 10626482A RO 84119 B1 RO84119 B1 RO 84119B1
- Authority
- RO
- Romania
- Prior art keywords
- nitroimidazole
- taken
- sulfuric acid
- hours
- over
- Prior art date
Links
- VYDWQPKRHOGLPA-UHFFFAOYSA-N 5-nitroimidazole Chemical compound [O-][N+](=O)C1=CN=CN1 VYDWQPKRHOGLPA-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 4
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 238000010790 dilution Methods 0.000 abstract 1
- 239000012895 dilution Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 229910017604 nitric acid Inorganic materials 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
- GMMSTIGHDDLCMI-UHFFFAOYSA-N zinc;imidazol-3-ide Chemical compound [Zn+2].C1=C[N-]C=N1.C1=C[N-]C=N1 GMMSTIGHDDLCMI-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Inventia se refera la un procedeu de obtinere a 4 (5)-nitroimidazolului, care foloseste ca materie prima imidazolatul de zinc, lucrarea decurgînd prin introducerea treptata a acestuia, în decurs de 4...5 h, peste un amestec sulfonitric preparat din acid sulfuric oleum de 20%, luat în raportul de 4,5 ml/l g imidazolat de zinc si acid azotic 98%, luat în raportul molar de 1:1 fata de imidazol, perfectarea reactiei timp de 3 h la temperatura de 25...30 degree C, diluarea masei prin turnare pe gheata, neutralizarea acidului sulfuric pîna la pH=1,5...2,5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO106264A RO84119B1 (ro) | 1982-01-08 | 1982-01-08 | Procedeu de obtinere a 4(5)-nitroimidazolului |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO106264A RO84119B1 (ro) | 1982-01-08 | 1982-01-08 | Procedeu de obtinere a 4(5)-nitroimidazolului |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO84119A2 RO84119A2 (ro) | 1984-05-12 |
| RO84119B1 true RO84119B1 (ro) | 1984-06-30 |
Family
ID=20110911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO106264A RO84119B1 (ro) | 1982-01-08 | 1982-01-08 | Procedeu de obtinere a 4(5)-nitroimidazolului |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO84119B1 (ro) |
-
1982
- 1982-01-08 RO RO106264A patent/RO84119B1/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO84119A2 (ro) | 1984-05-12 |
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