RO71305A - PROCESS FOR THE PREPARATION OF D-HALO-6-METHYL-2,8-CYANO- (CARBOXAMIDO) -GEROLINE - Google Patents

PROCESS FOR THE PREPARATION OF D-HALO-6-METHYL-2,8-CYANO- (CARBOXAMIDO) -GEROLINE

Info

Publication number
RO71305A
RO71305A RO7375548A RO7554873A RO71305A RO 71305 A RO71305 A RO 71305A RO 7375548 A RO7375548 A RO 7375548A RO 7554873 A RO7554873 A RO 7554873A RO 71305 A RO71305 A RO 71305A
Authority
RO
Romania
Prior art keywords
geroline
carboxamido
halo
cyano
methyl
Prior art date
Application number
RO7375548A
Other languages
French (fr)
Romanian (ro)
Inventor
James A Clemens
Edmund C Komfeld
Nicholas J Bach
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of RO71305A publication Critical patent/RO71305A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RO7375548A 1972-07-21 1973-07-20 PROCESS FOR THE PREPARATION OF D-HALO-6-METHYL-2,8-CYANO- (CARBOXAMIDO) -GEROLINE RO71305A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27390272A 1972-07-21 1972-07-21

Publications (1)

Publication Number Publication Date
RO71305A true RO71305A (en) 1982-03-24

Family

ID=23045910

Family Applications (2)

Application Number Title Priority Date Filing Date
RO7375548A RO71305A (en) 1972-07-21 1973-07-20 PROCESS FOR THE PREPARATION OF D-HALO-6-METHYL-2,8-CYANO- (CARBOXAMIDO) -GEROLINE
RO7300083213A RO63792A (en) 1972-07-21 1973-07-20 PROCESS FOR THE PREPARATION OF ERGOLINES-0-6-METHYL-2-8-SUBSTITUTED

Family Applications After (1)

Application Number Title Priority Date Filing Date
RO7300083213A RO63792A (en) 1972-07-21 1973-07-20 PROCESS FOR THE PREPARATION OF ERGOLINES-0-6-METHYL-2-8-SUBSTITUTED

Country Status (24)

Country Link
JP (2) JPS576431B2 (en)
AR (3) AR206772A1 (en)
AT (1) AT331425B (en)
BE (1) BE802531A (en)
BG (3) BG22400A3 (en)
CA (1) CA1006159A (en)
CH (5) CH580625A5 (en)
CS (1) CS208164B2 (en)
DD (1) DD107690A5 (en)
DE (2) DE2335750C3 (en)
DK (1) DK140986B (en)
ES (5) ES417078A1 (en)
FR (1) FR2193606B1 (en)
GB (1) GB1423065A (en)
HU (1) HU167274B (en)
IE (1) IE37936B1 (en)
IL (3) IL42730A (en)
NL (1) NL7309969A (en)
PH (1) PH11229A (en)
RO (2) RO71305A (en)
SE (3) SE393111B (en)
SU (3) SU645581A3 (en)
YU (1) YU36953B (en)
ZA (1) ZA734627B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
DE3587860D1 (en) * 1984-04-09 1994-07-28 Schering Ag 2-Substituted ergoline derivatives, process for their preparation and their use as medicines.
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (en) * 1986-06-16 1987-12-17 Schering Ag 1 AND / OR 2 SUBSTITUTED ERGOL DERIVATIVES
JPH0596382U (en) * 1992-05-28 1993-12-27 イビデン株式会社 Door unit

Also Published As

Publication number Publication date
SU645581A3 (en) 1979-01-30
CS208164B2 (en) 1981-08-31
IL42730A (en) 1976-06-30
NL7309969A (en) 1974-01-23
IL42730A0 (en) 1973-10-25
SU584780A3 (en) 1977-12-15
GB1423065A (en) 1976-01-28
ES442885A1 (en) 1977-04-16
JPS5813541B2 (en) 1983-03-14
JPS5781487A (en) 1982-05-21
CH580625A5 (en) 1976-10-15
SE393111B (en) 1977-05-02
DD107690A5 (en) 1974-08-12
DK140986C (en) 1980-07-21
BE802531A (en) 1974-01-21
SE7611467L (en) 1976-10-15
BG21410A3 (en) 1976-05-20
FR2193606B1 (en) 1977-07-15
AR206887A1 (en) 1976-08-31
AT331425B (en) 1976-08-25
CH580626A5 (en) 1976-10-15
SU575029A3 (en) 1977-09-30
ATA643473A (en) 1975-11-15
IE37936L (en) 1974-01-21
ZA734627B (en) 1974-06-26
IL48288A0 (en) 1975-12-31
DE2365974A1 (en) 1977-03-24
YU194573A (en) 1982-06-18
HU167274B (en) 1975-09-27
ES417078A1 (en) 1976-05-01
ES446789A1 (en) 1977-06-01
CH578563A5 (en) 1976-08-13
CH581135A5 (en) 1976-10-29
BG22400A3 (en) 1977-02-20
AR206772A1 (en) 1976-08-23
FR2193606A1 (en) 1974-02-22
AR210072A1 (en) 1977-06-30
IE37936B1 (en) 1977-11-23
BG21411A3 (en) 1976-05-20
IL48288A (en) 1976-06-30
JPS4985099A (en) 1974-08-15
CH578564A5 (en) 1976-08-13
PH11229A (en) 1977-10-28
ES442887A1 (en) 1977-05-16
SE410459B (en) 1979-10-15
JPS576431B2 (en) 1982-02-04
ES442886A1 (en) 1977-04-16
AU5792673A (en) 1975-01-16
RO63792A (en) 1978-12-15
YU36953B (en) 1984-08-31
DE2335750C3 (en) 1978-10-19
DE2335750B2 (en) 1978-02-23
DE2335750A1 (en) 1974-02-14
CA1006159A (en) 1977-03-01
DK140986B (en) 1979-12-17
SE410603B (en) 1979-10-22
SE7611466L (en) 1976-10-15

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