RO70755A - PROCESS FOR THE PREPARATION OF AROYL-PHENYL-1,2-DIHYDENOYNALINE DERIVATIVES - Google Patents

PROCESS FOR THE PREPARATION OF AROYL-PHENYL-1,2-DIHYDENOYNALINE DERIVATIVES

Info

Publication number
RO70755A
RO70755A RO7688227A RO8822776A RO70755A RO 70755 A RO70755 A RO 70755A RO 7688227 A RO7688227 A RO 7688227A RO 8822776 A RO8822776 A RO 8822776A RO 70755 A RO70755 A RO 70755A
Authority
RO
Romania
Prior art keywords
dihydenoynaline
aroyl
phenyl
derivatives
preparation
Prior art date
Application number
RO7688227A
Other languages
French (fr)
Romanian (ro)
Inventor
Tulio Suarez
Charles D Jones
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of RO70755A publication Critical patent/RO70755A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/455Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/245Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265Citric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
RO7688227A 1975-10-28 1976-10-26 PROCESS FOR THE PREPARATION OF AROYL-PHENYL-1,2-DIHYDENOYNALINE DERIVATIVES RO70755A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62599175A 1975-10-28 1975-10-28

Publications (1)

Publication Number Publication Date
RO70755A true RO70755A (en) 1981-01-30

Family

ID=24508491

Family Applications (1)

Application Number Title Priority Date Filing Date
RO7688227A RO70755A (en) 1975-10-28 1976-10-26 PROCESS FOR THE PREPARATION OF AROYL-PHENYL-1,2-DIHYDENOYNALINE DERIVATIVES

Country Status (30)

Country Link
JP (1) JPS6045191B2 (en)
AR (1) AR214622A1 (en)
AT (1) AT346321B (en)
AU (1) AU509372B2 (en)
BE (1) BE847716A (en)
BG (1) BG27555A3 (en)
CA (1) CA1078834A (en)
CH (2) CH624398A5 (en)
CS (1) CS235057B2 (en)
DD (1) DD127460A5 (en)
DE (1) DE2646213C2 (en)
DK (1) DK484776A (en)
ES (1) ES452735A1 (en)
FR (1) FR2329264A1 (en)
GB (1) GB1561687A (en)
GR (1) GR61816B (en)
HU (1) HU175227B (en)
IE (1) IE43641B1 (en)
IL (1) IL50772A (en)
MX (1) MX4291E (en)
NL (1) NL187164C (en)
NZ (1) NZ182421A (en)
PH (1) PH14538A (en)
PL (2) PL111987B1 (en)
PT (1) PT65752B (en)
RO (1) RO70755A (en)
SE (1) SE428689B (en)
SU (2) SU791220A3 (en)
YU (1) YU262276A (en)
ZA (1) ZA766439B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179558A (en) * 1978-01-30 1979-12-18 E. R. Squibb & Sons, Inc. Naphthalenone derivatives and analogs
DE3121175A1 (en) * 1981-05-27 1982-12-16 Klinge Pharma GmbH, 8000 München ERYTHRO-1,2,3-TRIPHENYL-1-PENTANONE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
JPH0717589B2 (en) * 1990-01-22 1995-03-01 ファイザー製薬株式会社 Novel 1,3-dicarbonyl compound and composition thereof
US6391892B1 (en) * 1995-03-10 2002-05-21 Eli Lilly And Company Naphthyl pharmaceutical compounds

Also Published As

Publication number Publication date
PT65752B (en) 1978-04-20
FR2329264B1 (en) 1978-11-17
IE43641L (en) 1977-04-28
CH624376A5 (en) 1981-07-31
JPS5253845A (en) 1977-04-30
CA1078834A (en) 1980-06-03
ZA766439B (en) 1978-06-28
ES452735A1 (en) 1978-01-01
AU509372B2 (en) 1980-05-08
IL50772A0 (en) 1976-12-31
NL7611974A (en) 1977-05-02
SU818476A3 (en) 1981-03-30
JPS6045191B2 (en) 1985-10-08
IE43641B1 (en) 1981-04-22
NZ182421A (en) 1978-11-13
SE7611953L (en) 1977-04-29
YU262276A (en) 1982-05-31
HU175227B (en) 1980-06-28
SE428689B (en) 1983-07-18
BG27555A3 (en) 1979-11-12
PL111987B1 (en) 1980-09-30
SU791220A3 (en) 1980-12-23
DE2646213A1 (en) 1977-05-12
NL187164B (en) 1991-01-16
MX4291E (en) 1982-03-17
GB1561687A (en) 1980-02-27
GR61816B (en) 1979-01-22
IL50772A (en) 1980-11-30
AR214622A1 (en) 1979-07-13
CS235057B2 (en) 1985-04-16
PT65752A (en) 1976-11-01
AU1900476A (en) 1978-05-04
DD127460A5 (en) 1977-09-28
FR2329264A1 (en) 1977-05-27
CH624398A5 (en) 1981-07-31
DK484776A (en) 1977-04-29
DE2646213C2 (en) 1987-02-12
BE847716A (en) 1977-04-28
PL104551B1 (en) 1979-08-31
NL187164C (en) 1991-06-17
PH14538A (en) 1981-09-24
ATA800576A (en) 1978-03-15
AT346321B (en) 1978-11-10

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