PT99065A - Construcoes de dna e metodo para a insercao de dna por transposoes modificados - Google Patents

Construcoes de dna e metodo para a insercao de dna por transposoes modificados Download PDF

Info

Publication number
PT99065A
PT99065A PT99065A PT9906591A PT99065A PT 99065 A PT99065 A PT 99065A PT 99065 A PT99065 A PT 99065A PT 9906591 A PT9906591 A PT 9906591A PT 99065 A PT99065 A PT 99065A
Authority
PT
Portugal
Prior art keywords
dna
transposase
gene
lambda
protein
Prior art date
Application number
PT99065A
Other languages
English (en)
Portuguese (pt)
Inventor
Robert Newton Brey Iii
Robert Allen Deich
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PT99065A publication Critical patent/PT99065A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT99065A 1990-09-28 1991-09-26 Construcoes de dna e metodo para a insercao de dna por transposoes modificados PT99065A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59036490A 1990-09-28 1990-09-28

Publications (1)

Publication Number Publication Date
PT99065A true PT99065A (pt) 1992-08-31

Family

ID=24361947

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99065A PT99065A (pt) 1990-09-28 1991-09-26 Construcoes de dna e metodo para a insercao de dna por transposoes modificados

Country Status (9)

Country Link
EP (1) EP0485701A1 (enExample)
JP (1) JPH0576376A (enExample)
KR (1) KR920006500A (enExample)
CA (1) CA2052324A1 (enExample)
FI (1) FI914565A7 (enExample)
IL (1) IL99440A0 (enExample)
NO (1) NO913814L (enExample)
PT (1) PT99065A (enExample)
TW (1) TW240246B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9115332D0 (en) * 1991-07-16 1991-08-28 Connaught Lab Manipulation of gene copy number in bordetella
FR2703996B1 (fr) * 1993-04-16 1995-07-21 Transgene Sa Ensemble de transposition destine au transfert d'un gene d'interet dans le genome d'une cellule eucaryote.
FR2736066B1 (fr) * 1995-06-30 1998-11-20 Ajinomoto Kk Procede d'amplification d'un gene par transposon artificiel, bacterie coryneforme obtenue par ce procede et procede de production d'un acide amine a l'aide de cette bacterie
FR2738842B1 (fr) * 1995-09-15 1997-10-31 Rhone Poulenc Rorer Sa Molecule d'adn circulaire a origine de replication conditionnelle, leur procede de preparation et leur utilisation en therapie genique
AU731615B2 (en) * 1996-02-09 2001-04-05 Het Nederlands Kanker Instituut Vectors and methods for providing cells with additional nucleic acid material integrated in the genome of said cells
KR20000076157A (ko) 1997-03-11 2000-12-26 리전츠 오브 더 유니버스티 오브 미네소타 세포의 디엔에이로 핵산을 도입하는 디엔에이-기초 전이인자 시스템
US6156574A (en) 1997-06-23 2000-12-05 The Rockefeller University Methods of performing gene trapping in bacterial and bacteriophage-derived artificial chromosomes and use thereof
US6821759B1 (en) 1997-06-23 2004-11-23 The Rockefeller University Methods of performing homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof
US7160682B2 (en) 1998-11-13 2007-01-09 Regents Of The University Of Minnesota Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
JP2002543792A (ja) * 1999-05-11 2002-12-24 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ ベクターによるトランスポゾン配列の供給及び組込み
WO2001005962A1 (en) * 1999-07-20 2001-01-25 The Rockefeller University Conditional homologous recombination of large genomic vector inserts
KR100470907B1 (ko) * 2002-04-20 2005-03-08 한국과학기술원 분자내 양방향 염색체 제거에 사용되는 트랜스포존, 이를이용한 미생물 변이주 제조 및 생장 비필수 유전자 선별방법
AU2003231048A1 (en) 2002-04-22 2003-11-03 Regents Of The University Of Minnesota Transposon system and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001646A1 (en) * 1986-08-26 1988-03-10 Allelix Inc. Universal system for transposon mutagenesis

Also Published As

Publication number Publication date
JPH0576376A (ja) 1993-03-30
CA2052324A1 (en) 1992-03-29
NO913814D0 (no) 1991-09-27
TW240246B (enExample) 1995-02-11
FI914565L (fi) 1992-03-29
NO913814L (no) 1992-03-30
FI914565A7 (fi) 1992-03-29
EP0485701A1 (en) 1992-05-20
KR920006500A (ko) 1992-04-27
IL99440A0 (en) 1992-08-18
FI914565A0 (fi) 1991-09-27

Similar Documents

Publication Publication Date Title
US7871604B1 (en) Recombinant bacterial vaccine system with environmentally limited viability
US7700104B2 (en) Attenuated Salmonella SP12 mutants as antigen carriers
ES2286905T3 (es) Sistema de estabilizacion de plasmidos para el suministro de antigenos.
KR100242798B1 (ko) 안정한 pur A 벡터 및 이의 사용
US5643771A (en) Non-reverting live bacterial vaccines
Ho et al. Characterization of grvA, an antivirulence gene on the gifsy-2 phage in Salmonella enterica serovar typhimurium
US6872547B1 (en) Functional balanced-lethal host-vector systems
US7056700B2 (en) Use of ClyA hemolysin for excretion of proteins
PT99065A (pt) Construcoes de dna e metodo para a insercao de dna por transposoes modificados
JP2003509008A (ja) 感染症の治療のための弱毒化微生物
AU2001297770A1 (en) Use of CLyA hemolysin for excretion of fusion proteins
Karem et al. Differential induction of carrier antigen-specific immunity by Salmonella typhimurium live-vaccine strains after single mucosal or intravenous immunization of BALB/c mice
ZA200105383B (en) Plasmid Maintenance System for antigen delivery.
US4761372A (en) Mutant enterotoxin of E. coli
US7943122B2 (en) Attenuated bacteria useful in vaccines
Mekalanos et al. Genetic mapping of toxin regulatory mutations in Vibrio cholerae
JPS6339588A (ja) 非抗生物質マ−カ−系
JP2009516503A (ja) 弱毒化ｓ・パラチフスａ菌株およびその使用
Husseiny et al. Construction of highly attenuated Salmonella enterica serovar Typhimurium live vectors for delivering heterologous antigens by chromosomal integration
Johnson et al. Vibrio cholerae conjugative plasmid pSJ15 contains transposable prophage dVcA1
US8076130B2 (en) Plasmid maintenance system for antigen delivery
EP0632834A1 (en) Microorganisms having attenuated invasiveness
AU653362B2 (en) Insertion of DNA by modified transposons
ALTMAN et al. Salmonella Species
Sarker et al. Gene Transfer in Enteric Bacteria through the Formation of R‐Prime Plasmids by an RP4:: Mini‐Mu Element

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920408

FC3A Refusal

Effective date: 19981117