PT97407A - Processo para a preparacao de (r)-9-{2-(fosfono-metoxi)-propil}-guanina - Google Patents

Processo para a preparacao de (r)-9-{2-(fosfono-metoxi)-propil}-guanina

Info

Publication number
PT97407A
PT97407A PT97407A PT9740791A PT97407A PT 97407 A PT97407 A PT 97407A PT 97407 A PT97407 A PT 97407A PT 9740791 A PT9740791 A PT 9740791A PT 97407 A PT97407 A PT 97407A
Authority
PT
Portugal
Prior art keywords
phospho
guanine
methoxy
propyl
preparation
Prior art date
Application number
PT97407A
Other languages
English (en)
Other versions
PT97407B (pt
Inventor
Kuo-Long Yu
Joanne J Bronson
John C Martin
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PT97407A publication Critical patent/PT97407A/pt
Publication of PT97407B publication Critical patent/PT97407B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
PT97407A 1990-04-20 1991-04-18 Processo para a preparacao de (r)-9-{2-(fosfono-metoxi)-propil}-guanina PT97407B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51169090A 1990-04-20 1990-04-20
US51330790A 1990-04-20 1990-04-20

Publications (2)

Publication Number Publication Date
PT97407A true PT97407A (pt) 1992-01-31
PT97407B PT97407B (pt) 1998-08-31

Family

ID=27057310

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97407A PT97407B (pt) 1990-04-20 1991-04-18 Processo para a preparacao de (r)-9-{2-(fosfono-metoxi)-propil}-guanina

Country Status (10)

Country Link
EP (1) EP0452935B1 (pt)
JP (1) JP3172801B2 (pt)
KR (1) KR100188554B1 (pt)
AT (1) ATE124050T1 (pt)
AU (1) AU643987B2 (pt)
CA (1) CA2040854C (pt)
DE (1) DE69110528T2 (pt)
FI (1) FI911875A (pt)
IE (1) IE68415B1 (pt)
PT (1) PT97407B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2087446A1 (en) * 1990-07-19 1992-01-20 Michael R. Harnden Antiviral phosphono-alken derivatives of purines
WO1993006112A1 (en) * 1991-09-24 1993-04-01 The Wellcome Foundation Limited Therapeutic nucleosides
US6057305A (en) * 1992-08-05 2000-05-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiretroviral enantiomeric nucleotide analogs
GB9226879D0 (en) * 1992-12-23 1993-02-17 Iaf Biochem Int Anti-viral compounds
US6444656B1 (en) 1992-12-23 2002-09-03 Biochem Pharma, Inc. Antiviral phosphonate nucleotides
US6005107A (en) * 1992-12-23 1999-12-21 Biochem Pharma, Inc. Antiviral compounds
US5877166A (en) * 1996-04-29 1999-03-02 Sri International Enantiomerically pure 2-aminopurine phosphonate nucleotide analogs as antiviral agents
DK2682397T3 (da) * 2000-07-21 2017-06-19 Gilead Sciences Inc Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same
EP3578563B1 (en) 2011-12-22 2021-04-14 Geron Corporation Guanine analogs as telomerase substrates and telomere length affectors
KR200488845Y1 (ko) * 2019-03-12 2019-07-31 임병철 엔진 구동 교육 장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
AU613592B2 (en) * 1986-11-18 1991-08-08 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiviral phosophonomethoxy-alkyene purine and pyrimide derivatives

Also Published As

Publication number Publication date
EP0452935B1 (en) 1995-06-21
DE69110528D1 (de) 1995-07-27
FI911875A (fi) 1991-10-21
AU7517191A (en) 1991-10-24
AU643987B2 (en) 1993-12-02
ATE124050T1 (de) 1995-07-15
JP3172801B2 (ja) 2001-06-04
PT97407B (pt) 1998-08-31
CA2040854C (en) 2000-11-21
DE69110528T2 (de) 1996-03-14
FI911875A0 (fi) 1991-04-18
KR910018393A (ko) 1991-11-30
CA2040854A1 (en) 1991-10-21
KR100188554B1 (ko) 1999-06-01
IE911321A1 (en) 1991-10-23
IE68415B1 (en) 1996-06-12
JPH0539297A (ja) 1993-02-19
EP0452935A1 (en) 1991-10-23

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Legal Events

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BB1A Laying open of patent application

Effective date: 19910912

FG3A Patent granted, date of granting

Effective date: 19980506

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20130506